Basic Information:

  VIRBase ID:  

HHID00069923

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-1304-5p:  MIMAT0005892          KDM6B:  NM_001080424     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-1304-5p	KDM6B
miRBase Accession/Entrez ID	MIMAT0005892	23135
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	JMJD3//NEDCFSA

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-1304-5p	rs1360520725 chr11:93733726    C/T rs1362552303 chr11:93733733    C/T rs749880345 chr11:93733735    G/A rs749880345 chr11:93733735    G/T rs780506580 chr11:93733725    A/C rs1411147958 chr11:93733742    C/T rs748549386 chr11:93733740    C/A rs76857625 chr11:93733744    A/G rs779470949 chr11:93733739    C/T rs780392471 chr11:93733739    C/CATTGAGCCCAGGGGTT rs79759099 chr11:93733743    A/G

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	KDM6B	chr17:7747557-7747558(+) m6A exon//intron       - chr17:7747630-7747631(+) m6A exon//intron       26404942 chr17:7747656-7747657(+) m6A exon//intron       26404942 chr17:7747666-7747667(+) m6A exon//intron       26404942 chr17:7748236-7748237(+) m6A 5'UTR//exon       26404942 chr17:7748647-7748648(+) m6A 5'UTR//exon       24284625//26404942 chr17:7749524-7749525(+) Tm CDS       - chr17:7750054-7750055(+) m6A CDS       24284625 chr17:7750624-7750625(+) m6A CDS       24284625 chr17:7750759-7750760(+) m6A CDS       24284625 chr17:7750884-7750885(+) m6A CDS       24284625 chr17:7750946-7750947(+) m6A CDS       24284625//24981863 chr17:7750997-7750998(+) m6A CDS       24284625//24981863 chr17:7751127-7751128(+) m6A CDS       25456834//24981863 chr17:7751135-7751136(+) m6A CDS       24284625//25456834//24981863 chr17:7751350-7751351(+) m6A CDS       24284625//24209618//24981863 chr17:7751383-7751384(+) m6A CDS       24284625//24209618//24981863 chr17:7751392-7751393(+) m6A CDS       24284625//24209618//24981863 chr17:7751514-7751515(+) m6A CDS       24284625 chr17:7751644-7751645(+) m6A CDS       24284625//26404942 chr17:7751738-7751739(+) m6A CDS       24284625//26404942 chr17:7751913-7751914(+) m1A CDS       26863196 chr17:7752044-7752045(+) m6A CDS       24284625//24209618//25456834//24981863//26404942 chr17:7752066-7752067(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960 chr17:7752372-7752373(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27371828//22575960//22608085 chr17:7752424-7752425(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27371828//22575960//22608085 chr17:7752442-7752443(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27371828//22575960//22608085 chr17:7752450-7752451(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27371828//22575960//22608085 chr17:7752580-7752581(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27371828//22575960//22608085 chr17:7752664-7752665(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27371828 chr17:7752670-7752671(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//27371828 chr17:7752954-7752955(+) m6A CDS       24284625 chr17:7753000-7753001(+) m6A CDS       24284625 chr17:7753198-7753199(+) m6A CDS       24284625//26404942 chr17:7753237-7753238(+) m6A CDS       24284625//26404942 chr17:7753441-7753442(+) m6A CDS       24284625 chr17:7754687-7754688(+) m6A CDS       25456834 chr17:7754701-7754702(+) m6A CDS       25456834 chr17:7754806-7754807(+) m6A CDS       25456834 chr17:7754815-7754816(+) m6A CDS       25456834 chr17:7755564-7755565(+) m6A CDS       26404942 chr17:7755587-7755588(+) m6A CDS       26404942 chr17:7756997-7756998(+) m6A 3'UTR       26404942 chr17:7757121-7757122(+) m6A 3'UTR       24981863//26404942 chr17:7757129-7757130(+) m6A 3'UTR       24981863//26404942 chr17:7757440-7757441(+) m6A 3'UTR       - chr17:7757486-7757487(+) m6A 3'UTR       - chr17:7757592-7757593(+) m6A 3'UTR       24284625 chr17:7757628-7757629(+) m6A 3'UTR       24284625 chr17:7757707-7757708(+) m6A 3'UTR       24981863 chr17:7757770-7757771(+) m6A 3'UTR       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-1304-5p	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Fibroblasts|Mesenchymal stem cells     -
	KDM6B	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleolus K562 cells     - Nucleus K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-1304-5p
Interactor2: KDM6B

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.