Detail Information

Basic Information:


  VIRBase ID:  

HHID00069801

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-548l:           MYLIP:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-548l MYLIP
miRBase
Accession/Entrez ID		 MIMAT0005889 29116
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - IDOL//MIR

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-548l
rs13447640 chr11:94466555    G/A
rs13447640 chr11:94466555    G/T
rs1448088579 chr11:94466547    C/A
rs148377174 chr11:94466545    G/A
rs148377174 chr11:94466545    G/T
rs759436685 chr11:94466554    C/T
rs762603325 chr11:94466558    A/C
rs1289439065 chr11:94466561    AC/A
rs1331201116 chr11:94466562    C/G
rs1410886742 chr11:94466561    A/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR MYLIP
chr6:16139521(+) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase MYLIP
chr6:16129419-16129420(+) m6A 5'UTR       24284625//24981863
chr6:16129626-16129627(+) m6A 5'UTR//CDS       24284625//24209618
chr6:16130828-16130829(+) m6A CDS//intron       24284625
chr6:16145210-16145211(+) m6A CDS       24284625//25456834//24981863//22575960//22608085
chr6:16145251-16145252(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr6:16145309-16145310(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr6:16145324-16145325(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr6:16145375-16145376(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr6:16145410-16145411(+) m6A CDS       24284625//25456834//24981863//22575960//22608085
chr6:16147001-16147002(+) m6A 3'UTR       24284625//24209618//24981863//22575960//22608085
chr6:16147020-16147021(+) m6A 3'UTR       24284625//24209618//24981863//22608085
chr6:16147035-16147036(+) m6A 3'UTR       24284625//24209618//24981863//22608085
chr6:16147148-16147149(+) m6A 3'UTR       24284625//24981863//22608085
chr6:16147186-16147187(+) m6A 3'UTR       24284625//22608085
chr6:16147210-16147211(+) m6A 3'UTR       -

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-548l
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
MYLIP
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleoplasm K562 cells     -
Nucleus K562 cells     -
Ribosome HEK-293 cells     22199352

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-548l
Interactor2: MYLIP

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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