Detail Information

Basic Information:


  VIRBase ID:  

HHID00069674

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-1294 IGKC
miRBase
Accession/Entrez ID		 MIMAT0005884 3514
Organism Homo sapiens Homo sapiens
Category miRNA other
Alias - HCAK1//IGKCD//Km

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-1294
rs1162939290 chr5:154347163    G/T
rs1179835339 chr5:154347171    G/GTATA
rs1237976003 chr5:154347166    T/C
rs1255234532 chr5:154347174    T/A
rs1465013068 chr5:154347169    T/C
rs189565536 chr5:154347168    G/T
rs1211754242 chr5:154347158    G/A
rs1341512450 chr5:154347155    T/G

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase IGKC
chr2:89156954-89156955(-) m6A CDS       27371828
chr2:89156964-89156965(-) m6A CDS       27371828
chr2:89157009-89157010(-) m6A CDS       27371828
chr2:89157018-89157019(-) m6A CDS       27371828
chr2:89157133-89157134(-) m6A CDS       -
chr2:89157193-89157194(-) m6A CDS       -
chr2:89160415-89160416(-) m6A CDS//intron       -
chr2:89161054-89161055(-) m6A CDS//intron       -
chr2:89165169-89165170(-) m6A intron       -
chr2:89165176-89165177(-) m6A intron       -
chr2:89165222-89165223(-) m6A intron       -
chr2:89165284-89165285(-) m6A intron       -
chr2:89231186-89231187(-) m6A CDS//intron       -

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-1294
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Serum     24797360
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-1294
Interactor2: IGKC

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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