Basic Information:

  VIRBase ID:  

HHID00069662

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-1294:  MIMAT0005884          NLRX1:  NM_001282358     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-1294	NLRX1
miRBase Accession/Entrez ID	MIMAT0005884	79671
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	CLR11.3//DLNB26//NOD26//NOD5//NOD9

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-1294	rs1162939290 chr5:154347163    G/T rs1179835339 chr5:154347171    G/GTATA rs1237976003 chr5:154347166    T/C rs1255234532 chr5:154347174    T/A rs1465013068 chr5:154347169    T/C rs189565536 chr5:154347168    G/T rs1211754242 chr5:154347158    G/A rs1341512450 chr5:154347155    T/G

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	NLRX1	chr11:119047903(+) A-I      intronic chr11:119048217(+) A-I      ncRNA chr11:119048319(+) A-I      ncRNA chr11:119048266(+) A-I      ncRNA chr11:119048262(+) A-I      ncRNA chr11:119047891(+) A-I      intronic chr11:119047980(+) A-I      intronic chr11:119048816(+) A-I      intronic chr11:119047810(+) A-I      intronic chr11:119049435(+) A-I      intronic chr11:119048852(+) A-I      intronic chr11:119040608(+) A-I      intronic chr11:119047146(+) A-I      intronic chr11:119048249(+) A-I      ncRNA chr11:119048161(+) A-I      intronic chr11:119049594(+) A-I      intronic chr11:119047930(+) A-I      intronic chr11:119050086(+) A-I      intronic chr11:119048826(+) A-I      intronic chr11:119049519(+) A-I      intronic chr11:119048803(+) A-I      intronic chr11:119047346(+) A-I      intronic chr11:119047852(+) A-I      intronic chr11:119041758(+) A-I      intronic chr11:119049668(+) A-I      intronic chr11:119047103(+) A-I      intronic chr11:119050134(+) A-I      intronic chr11:119041732(+) A-I      intronic chr11:119047005(+) A-I      intronic chr11:119048779(+) A-I      intronic chr11:119050089(+) A-I      intronic chr11:119047298(+) A-I      intronic chr11:119047138(+) A-I      intronic chr11:119047871(+) A-I      intronic chr11:119047920(+) A-I      intronic chr11:119041959(+) A-I      intronic chr11:119050144(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	NLRX1	chr11:119047005(+) A-G intron -    22484847 chr11:119050092(+) C-T intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	NLRX1	chr11:119039200-119039201(+) m6A 5'UTR//intron       24981863 chr11:119039552-119039553(+) m6A 5'UTR//exon//intron       24284625//24981863 chr11:119039663-119039664(+) m6A 5'UTR//exon//intron       - chr11:119044277-119044278(+) m6A CDS//exon       24284625 chr11:119044438-119044439(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr11:119044456-119044457(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr11:119044502-119044503(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr11:119044559-119044560(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22575960//22608085 chr11:119044728-119044729(+) m6A CDS//exon       24284625 chr11:119044749-119044750(+) m6A CDS//exon       24284625 chr11:119044758-119044759(+) m6A CDS//exon       24284625 chr11:119045381-119045382(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22608085 chr11:119045488-119045489(+) m6A CDS//exon       24284625//24209618//25456834//24981863//22608085 chr11:119045539-119045540(+) m6A CDS//exon       24284625//25456834//24981863//22608085 chr11:119045546-119045547(+) m6A CDS//exon       24284625//25456834//24981863//22608085 chr11:119045593-119045594(+) m6A CDS//exon       24284625//25456834//24981863//22608085 chr11:119045635-119045636(+) m6A CDS//exon       24284625//25456834//24981863//22608085 chr11:119048533-119048534(+) m6A exon//intron       25456834 chr11:119050489-119050490(+) m6A CDS//exon       24284625//24981863 chr11:119050513-119050514(+) m6A CDS//exon       24284625//24981863 chr11:119050672-119050673(+) m6A CDS//exon       24284625 chr11:119050789-119050790(+) m6A CDS//exon       24284625 chr11:119050921-119050922(+) m6A CDS//exon       24284625//25456834//24981863 chr11:119051917-119051918(+) m6A CDS//exon       24284625//25456834 chr11:119051926-119051927(+) m6A CDS//exon       24284625//25456834 chr11:119052942-119052943(+) m6A CDS       24284625 chr11:119053045-119053046(+) m6A CDS       24284625 chr11:119053873-119053874(+) m6A CDS//intron       24284625 chr11:119053978-119053979(+) m6A CDS//intron       24284625//25456834 chr11:119054149-119054150(+) m6A 3'UTR//intron       24284625//24981863 chr11:119054191-119054192(+) m6A 3'UTR//intron       24284625//25456834//24981863//22608085 chr11:119054312-119054313(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//22608085 chr11:119054372-119054373(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//22608085 chr11:119054401-119054402(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//22575960//22608085 chr11:119054587-119054588(+) m6A 3'UTR//CDS       24284625//24981863//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-1294	Exosome Plasma     23663360 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Serum     24797360 Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
	NLRX1	Exosome Blood     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-1294
Interactor2: NLRX1

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.