Basic Information:

  VIRBase ID:  

HHID00069652

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-1294:  MIMAT0005884          ZSWIM6:  NM_020928     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-1294	ZSWIM6
miRBase Accession/Entrez ID	MIMAT0005884	57688
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	AFND//NEDMAGA

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-1294	rs1162939290 chr5:154347163    G/T rs1179835339 chr5:154347171    G/GTATA rs1237976003 chr5:154347166    T/C rs1255234532 chr5:154347174    T/A rs1465013068 chr5:154347169    T/C rs189565536 chr5:154347168    G/T rs1211754242 chr5:154347158    G/A rs1341512450 chr5:154347155    T/G

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	ZSWIM6	chr5:60635069(+) A-I      intronic chr5:60674643(+) A-I      intronic chr5:60674522(+) A-I      intronic chr5:60674460(+) A-I      intronic chr5:60674439(+) A-I      intronic chr5:60673456(+) A-I      intronic chr5:60663869(+) A-I      intronic chr5:60663734(+) A-I      intronic chr5:60663714(+) A-I      intronic chr5:60663692(+) A-I      intronic chr5:60679997(+) A-I      intronic chr5:60663686(+) A-I      intronic chr5:60663674(+) A-I      intronic chr5:60663355(+) A-I      intronic chr5:60663157(+) A-I      intronic chr5:60663107(+) A-I      intronic chr5:60662755(+) A-I      intronic chr5:60635073(+) A-I      intronic chr5:60674856(+) A-I      intronic chr5:60674842(+) A-I      intronic chr5:60635072(+) A-I      intronic chr5:60680002(+) A-I      intronic chr5:60683462(+) A-I      intronic chr5:60683909(+) A-I      intronic chr5:60683971(+) A-I      intronic chr5:60641871(+) A-I      intronic chr5:60641872(+) A-I      intronic chr5:60641977(+) A-I      intronic chr5:60659903(+) A-I      intronic chr5:60659975(+) A-I      intronic chr5:60689450(+) A-I      intronic chr5:60689458(+) A-I      intronic chr5:60717024(+) A-I      intronic chr5:60719048(+) A-I      intronic chr5:60719052(+) A-I      intronic chr5:60724304(+) A-I      intronic chr5:60724418(+) A-I      intronic chr5:60724472(+) A-I      intronic chr5:60745254(+) A-I      intronic chr5:60674797(+) A-I      intronic chr5:60801775(+) A-I      intronic chr5:60661931(+) A-I      intronic chr5:60661997(+) A-I      intronic chr5:60662615(+) A-I      intronic chr5:60662706(+) A-I      intronic chr5:60662715(+) A-I      intronic chr5:60683556(+) A-I      intronic chr5:60801780(+) A-I      intronic chr5:60825024(+) A-I      intronic chr5:60825025(+) A-I      intronic chr5:60632503(+) A-I      intronic chr5:60754611(+) A-I      intronic chr5:60754620(+) A-I      intronic chr5:60754630(+) A-I      intronic chr5:60754644(+) A-I      intronic chr5:60662725(+) A-I      intronic chr5:60824544(+) A-I      intronic chr5:60676003(+) A-I      intronic chr5:60663214(+) A-I      intronic chr5:60663183(+) A-I      intronic chr5:60683591(+) A-I      intronic chr5:60824946(+) A-I      intronic chr5:60824954(+) A-I      intronic chr5:60724433(+) A-I      intronic chr5:60824532(+) A-I      intronic chr5:60745257(+) A-I      intronic chr5:60825017(+) A-I      intronic chr5:60632461(+) A-I      intronic chr5:60632462(+) A-I      intronic chr5:60632479(+) A-I      intronic chr5:60679813(+) A-I      intronic chr5:60679554(+) A-I      intronic chr5:60632488(+) A-I      intronic chr5:60632491(+) A-I      intronic chr5:60802228(+) A-I      intronic chr5:60802226(+) A-I      intronic chr5:60802333(+) A-I      intronic chr5:60679540(+) A-I      intronic chr5:60679539(+) A-I      intronic chr5:60678602(+) A-I      intronic chr5:60678582(+) A-I      intronic chr5:60678538(+) A-I      intronic chr5:60678534(+) A-I      intronic chr5:60678521(+) A-I      intronic chr5:60678511(+) A-I      intronic chr5:60678470(+) A-I      intronic chr5:60678468(+) A-I      intronic chr5:60678430(+) A-I      intronic chr5:60678421(+) A-I      intronic chr5:60676969(+) A-I      intronic chr5:60676959(+) A-I      intronic chr5:60676933(+) A-I      intronic chr5:60676900(+) A-I      intronic chr5:60675014(+) A-I      intronic chr5:60802289(+) A-I      intronic chr5:60674929(+) A-I      intronic chr5:60802283(+) A-I      intronic chr5:60641836(+) A-I      intronic chr5:60635086(+) A-I      intronic chr5:60714151(+) A-I      intronic chr5:60674861(+) A-I      intronic chr5:60673424(+) A-I      intronic chr5:60688504(+) A-I      intronic chr5:60673389(+) A-I      intronic chr5:60661085(+) A-I      intronic chr5:60679576(+) A-I      intronic chr5:60674887(+) A-I      intronic chr5:60727069(+) A-I      intronic chr5:60688579(+) A-I      intronic chr5:60674941(+) A-I      intronic chr5:60683558(+) A-I      intronic chr5:60676655(+) A-I      intronic chr5:60824494(+) A-I      intronic chr5:60753571(+) A-I      intronic chr5:60674858(+) A-I      intronic chr5:60679648(+) A-I      intronic chr5:60720822(+) A-I      intronic chr5:60724207(+) A-I      intronic chr5:60726943(+) A-I      intronic chr5:60679503(+) A-I      intronic chr5:60824515(+) A-I      intronic chr5:60719144(+) A-I      intronic chr5:60678571(+) A-I      intronic chr5:60678517(+) A-I      intronic chr5:60712706(+) A-I      intronic chr5:60688496(+) A-I      intronic chr5:60662635(+) A-I      intronic chr5:60692238(+) A-I      intronic chr5:60802155(+) A-I      intronic chr5:60659972(+) A-I      intronic chr5:60729576(+) A-I      intronic chr5:60685262(+) A-I      intronic chr5:60679529(+) A-I      intronic chr5:60724240(+) A-I      intronic chr5:60720744(+) A-I      intronic chr5:60662681(+) A-I      intronic chr5:60679382(+) A-I      intronic chr5:60675967(+) A-I      intronic chr5:60674949(+) A-I      intronic chr5:60674743(+) A-I      intronic chr5:60674897(+) A-I      intronic chr5:60824991(+) A-I      intronic chr5:60688539(+) A-I      intronic chr5:60720823(+) A-I      intronic chr5:60824955(+) A-I      intronic chr5:60678465(+) A-I      intronic chr5:60683927(+) A-I      intronic chr5:60679389(+) A-I      intronic chr5:60714195(+) A-I      intronic chr5:60674585(+) A-I      intronic chr5:60824941(+) A-I      intronic chr5:60712712(+) A-I      intronic chr5:60678455(+) A-I      intronic chr5:60720755(+) A-I      intronic chr5:60662677(+) A-I      intronic chr5:60662613(+) A-I      intronic chr5:60632407(+) A-I      intronic chr5:60719115(+) A-I      intronic chr5:60689506(+) A-I      intronic chr5:60679654(+) A-I      intronic chr5:60673390(+) A-I      intronic chr5:60679814(+) A-I      intronic chr5:60674765(+) A-I      intronic chr5:60731774(+) A-I      intronic chr5:60674592(+) A-I      intronic chr5:60662000(+) A-I      intronic chr5:60716886(+) A-I      intronic chr5:60719088(+) A-I      intronic chr5:60802156(+) A-I      intronic chr5:60754558(+) A-I      intronic chr5:60637887(+) A-I      intronic chr5:60674509(+) A-I      intronic chr5:60688540(+) A-I      intronic chr5:60674901(+) A-I      intronic chr5:60674524(+) A-I      intronic chr5:60661883(+) A-I      intronic chr5:60824921(+) A-I      intronic chr5:60716982(+) A-I      intronic chr5:60683578(+) A-I      intronic chr5:60674940(+) A-I      intronic chr5:60720658(+) A-I      intronic chr5:60661763(+) A-I      intronic chr5:60712707(+) A-I      intronic chr5:60632852(+) A-I      intronic chr5:60674463(+) A-I      intronic chr5:60689515(+) A-I      intronic chr5:60714194(+) A-I      intronic chr5:60676960(+) A-I      intronic chr5:60659923(+) A-I      intronic chr5:60824983(+) A-I      intronic chr5:60674567(+) A-I      intronic chr5:60662609(+) A-I      intronic chr5:60678552(+) A-I      intronic chr5:60688966(+) A-I      intronic chr5:60683573(+) A-I      intronic chr5:60661922(+) A-I      intronic chr5:60754594(+) A-I      intronic chr5:60661762(+) A-I      intronic chr5:60663349(+) A-I      intronic chr5:60683990(+) A-I      intronic chr5:60679636(+) A-I      intronic chr5:60662704(+) A-I      intronic chr5:60661896(+) A-I      intronic chr5:60679432(+) A-I      intronic chr5:60663771(+) A-I      intronic chr5:60720684(+) A-I      intronic chr5:60660011(+) A-I      intronic chr5:60683262(+) A-I      intronic chr5:60683572(+) A-I      intronic chr5:60662610(+) A-I      intronic chr5:60683994(+) A-I      intronic chr5:60632844(+) A-I      intronic chr5:60754495(+) A-I      intronic chr5:60674885(+) A-I      intronic chr5:60714252(+) A-I      intronic chr5:60659957(+) A-I      intronic chr5:60674999(+) A-I      intronic chr5:60663132(+) A-I      intronic chr5:60662505(+) A-I      intronic chr5:60641933(+) A-I      intronic chr5:60824698(+) A-I      intronic chr5:60689572(+) A-I      intronic chr5:60727093(+) A-I      intronic chr5:60824984(+) A-I      intronic chr5:60679519(+) A-I      intronic chr5:60673494(+) A-I      intronic chr5:60674630(+) A-I      intronic chr5:60674512(+) A-I      intronic chr5:60661813(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	ZSWIM6	chr5:60671169(+) A-I intron -    22327324 chr5:60663132(+) A-I intron -    21960545 chr5:60663183(+) A-I intron -    21960545 chr5:60673397(+) A-I intron -    21960545 chr5:60659923(+) A-G intron -    22484847 chr5:60659957(+) A-G intron -    22484847 chr5:60659984(+) A-G intron -    22484847 chr5:60661058(+) A-G intron -    22484847 chr5:60661081(+) A-G intron -    22484847 chr5:60661762(+) A-G intron -    22484847 chr5:60661763(+) A-G intron -    22484847 chr5:60661813(+) A-G intron -    22484847 chr5:60661826(+) A-G intron -    22484847 chr5:60661883(+) A-G intron -    22484847 chr5:60661922(+) A-G intron -    22484847 chr5:60662000(+) A-G intron -    22484847 chr5:60663132(+) A-G intron -    22484847 chr5:60663152(+) A-G intron -    22484847 chr5:60674476(+) A-G intron -    22484847 chr5:60674592(+) A-G intron -    22484847 chr5:60674743(+) A-G intron -    22484847 chr5:60674765(+) A-G intron -    22484847 chr5:60679389(+) A-G intron -    22484847 chr5:60679814(+) A-G intron -    22484847 chr5:60688539(+) A-G intron -    22484847 chr5:60688966(+) A-G intron -    22484847 chr5:60699973(+) T-C intron -    22484847 chr5:60824983(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	ZSWIM6	chr5:60628113-60628114(+) m6A CDS       24981863 chr5:60628309-60628310(+) m6A CDS       24209618 chr5:60628334-60628335(+) m6A CDS       24284625//24209618 chr5:60628738-60628739(+) Y CDS       26075521 chr5:60628757-60628758(+) m6A CDS       24209618 chr5:60643329-60643330(+) m6A intron       22575960 chr5:60643347-60643348(+) m6A intron       22575960 chr5:60643365-60643366(+) m6A intron       22575960 chr5:60643373-60643374(+) m6A intron       22575960 chr5:60671140-60671141(+) m6A intron       27773535 chr5:60671153-60671154(+) m6A intron       27773535 chr5:60671162-60671163(+) m6A intron       27773535 chr5:60671210-60671211(+) m6A intron       27773535 chr5:60671601-60671602(+) m6A intron       27773535 chr5:60671627-60671628(+) m6A intron       27773535 chr5:60768535-60768536(+) m6A CDS       24209618//24981863//22608085 chr5:60768560-60768561(+) m6A CDS       24209618//24981863//22608085 chr5:60768627-60768628(+) m6A CDS       24284625//24981863//22608085 chr5:60768633-60768634(+) m6A CDS       24284625//24981863//22608085 chr5:60768700-60768701(+) m6A CDS       24284625//24981863//22608085 chr5:60768722-60768723(+) m6A CDS       24284625//24981863//22608085 chr5:60768744-60768745(+) m6A CDS       24284625//24981863//22608085 chr5:60821635-60821636(+) m6A CDS       - chr5:60821649-60821650(+) m6A CDS       - chr5:60821764-60821765(+) m6A CDS       - chr5:60839296-60839297(+) m6A CDS       24284625//24209618//24981863 chr5:60839310-60839311(+) m6A CDS       24284625//24209618//24981863//22608085 chr5:60839401-60839402(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr5:60839439-60839440(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr5:60839476-60839477(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr5:60839686-60839687(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr5:60839812-60839813(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr5:60839855-60839856(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr5:60839872-60839873(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr5:60839896-60839897(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr5:60840027-60840028(+) m6A CDS       24284625//24209618//24981863//27773535//22575960//22608085 chr5:60840050-60840051(+) m6A CDS       24284625//24209618//24981863//27773535//22575960//22608085 chr5:60840086-60840087(+) m6A CDS       24284625//24209618//24981863//27773535//22608085 chr5:60840110-60840111(+) m6A CDS       24284625//24209618//24981863//27773535//22608085 chr5:60840516-60840517(+) m6A 3'UTR       24981863 chr5:60840521-60840522(+) m6A 3'UTR       24981863 chr5:60840526-60840527(+) m6A 3'UTR       24981863 chr5:60840609-60840610(+) m6A 3'UTR       24981863 chr5:60840712-60840713(+) m6A 3'UTR       24981863 chr5:60840899-60840900(+) m6A 3'UTR       24981863//22608085 chr5:60840905-60840906(+) m6A 3'UTR       24981863//22608085 chr5:60840916-60840917(+) m6A 3'UTR       24981863//22608085 chr5:60840927-60840928(+) m6A 3'UTR       24981863//22608085 chr5:60840940-60840941(+) m6A 3'UTR       24981863//22608085 chr5:60840981-60840982(+) m6A 3'UTR       24981863//22608085 chr5:60841031-60841032(+) m6A 3'UTR       24981863//22608085 chr5:60841111-60841112(+) m6A 3'UTR       24981863//27773535//22608085 chr5:60841182-60841183(+) m6A 3'UTR       24981863//27773535//22608085 chr5:60841271-60841272(+) m6A 3'UTR       24981863 chr5:60841300-60841301(+) m6A 3'UTR       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-1294	Exosome Plasma     23663360 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Serum     24797360 Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
	ZSWIM6	Chromatin K562 cells     - Cytosol HeLa-S3 cells     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-1294
Interactor2: ZSWIM6

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	CDS
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.