Basic Information:

  VIRBase ID:  

HHID00069650

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-1294:  MIMAT0005884          DIABLO:  NM_001371333     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-1294	DIABLO
miRBase Accession/Entrez ID	MIMAT0005884	56616
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	DFNA64//SMAC

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-1294	rs1162939290 chr5:154347163    G/T rs1179835339 chr5:154347171    G/GTATA rs1237976003 chr5:154347166    T/C rs1255234532 chr5:154347174    T/A rs1465013068 chr5:154347169    T/C rs189565536 chr5:154347168    G/T rs1211754242 chr5:154347158    G/A rs1341512450 chr5:154347155    T/G

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	DIABLO	chr12:122708459(-) A-I      intronic chr12:122695519(-) A-I      intronic chr12:122708469(-) A-I      intronic chr12:122708529(-) A-I      intronic chr12:122708560(-) A-I      intronic chr12:122708574(-) A-I      intronic chr12:122695576(-) A-I      intronic chr12:122698985(-) A-I      intronic chr12:122698825(-) A-I      intronic chr12:122698628(-) A-I      intronic chr12:122698618(-) A-I      intronic chr12:122699090(-) A-I      intronic chr12:122698580(-) A-I      intronic chr12:122698520(-) A-I      intronic chr12:122698475(-) A-I      intronic chr12:122699161(-) A-I      intronic chr12:122698469(-) A-I      intronic chr12:122698389(-) A-I      intronic chr12:122698373(-) A-I      intronic chr12:122699172(-) A-I      intronic chr12:122699406(-) A-I      intronic chr12:122697963(-) A-I      intronic chr12:122697946(-) A-I      intronic chr12:122697885(-) A-I      intronic chr12:122697872(-) A-I      intronic chr12:122697860(-) A-I      intronic chr12:122697859(-) A-I      intronic chr12:122697851(-) A-I      intronic chr12:122699413(-) A-I      intronic chr12:122699415(-) A-I      intronic chr12:122697832(-) A-I      intronic chr12:122697664(-) A-I      intronic chr12:122699814(-) A-I      intronic chr12:122697570(-) A-I      intronic chr12:122699824(-) A-I      intronic chr12:122699900(-) A-I      intronic chr12:122699909(-) A-I      intronic chr12:122697557(-) A-I      intronic chr12:122700007(-) A-I      intronic chr12:122700088(-) A-I      intronic chr12:122700089(-) A-I      intronic chr12:122700321(-) A-I      intronic chr12:122700341(-) A-I      intronic chr12:122700358(-) A-I      intronic chr12:122697498(-) A-I      intronic chr12:122700367(-) A-I      intronic chr12:122701897(-) A-I      intronic chr12:122697497(-) A-I      intronic chr12:122697375(-) A-I      intronic chr12:122701943(-) A-I      intronic chr12:122697370(-) A-I      intronic chr12:122697344(-) A-I      intronic chr12:122697339(-) A-I      intronic chr12:122701950(-) A-I      intronic chr12:122697300(-) A-I      intronic chr12:122697202(-) A-I      intronic chr12:122702240(-) A-I      intronic chr12:122696664(-) A-I      intronic chr12:122696609(-) A-I      intronic chr12:122696184(-) A-I      intronic chr12:122696176(-) A-I      intronic chr12:122696149(-) A-I      intronic chr12:122696064(-) A-I      intronic chr12:122695830(-) A-I      intronic chr12:122695821(-) A-I      intronic chr12:122695764(-) A-I      intronic chr12:122695755(-) A-I      intronic chr12:122695750(-) A-I      intronic chr12:122695031(-) A-I      intronic chr12:122694996(-) A-I      intronic chr12:122702319(-) A-I      intronic chr12:122694920(-) A-I      intronic chr12:122704210(-) A-I      intronic chr12:122704219(-) A-I      intronic chr12:122704301(-) A-I      intronic chr12:122704310(-) A-I      intronic chr12:122704599(-) A-I      intronic chr12:122704611(-) A-I      intronic chr12:122704639(-) A-I      intronic chr12:122704710(-) A-I      intronic chr12:122704712(-) A-I      intronic chr12:122704765(-) A-I      intronic chr12:122704999(-) A-I      intronic chr12:122705039(-) A-I      intronic chr12:122705080(-) A-I      intronic chr12:122705090(-) A-I      intronic chr12:122705115(-) A-I      intronic chr12:122705116(-) A-I      intronic chr12:122705120(-) A-I      intronic chr12:122705140(-) A-I      intronic chr12:122706016(-) A-I      intronic chr12:122706028(-) A-I      intronic chr12:122706150(-) A-I      intronic chr12:122706161(-) A-I      intronic chr12:122706172(-) A-I      intronic chr12:122706233(-) A-I      intronic chr12:122706956(-) A-I      intronic chr12:122707087(-) A-I      intronic chr12:122697834(-) A-I      intronic chr12:122707860(-) A-I      intronic chr12:122707895(-) A-I      intronic chr12:122707942(-) A-I      intronic chr12:122707979(-) A-I      intronic chr12:122708445(-) A-I      intronic chr12:122708450(-) A-I      intronic chr12:122708494(-) A-I      intronic chr12:122708518(-) A-I      intronic chr12:122708519(-) A-I      intronic chr12:122708550(-) A-I      intronic chr12:122708551(-) A-I      intronic chr12:122708628(-) A-I      intronic chr12:122695147(-) A-I      intronic chr12:122699065(-) A-I      intronic chr12:122699041(-) A-I      intronic chr12:122695414(-) A-I      intronic chr12:122699392(-) A-I      intronic chr12:122699407(-) A-I      intronic chr12:122706960(-) A-I      intronic chr12:122695044(-) A-I      intronic chr12:122702276(-) A-I      intronic chr12:122697894(-) A-I      intronic chr12:122708455(-) A-I      intronic chr12:122699527(-) A-I      intronic chr12:122699714(-) A-I      intronic chr12:122693798(-) A-I      intronic chr12:122707838(-) A-I      intronic chr12:122698037(-) A-I      intronic chr12:122707943(-) A-I      intronic chr12:122698388(-) A-I      intronic chr12:122695423(-) A-I      intronic chr12:122696658(-) A-I      intronic chr12:122698811(-) A-I      intronic chr12:122695048(-) A-I      intronic chr12:122695121(-) A-I      intronic chr12:122703245(-) A-I      intronic chr12:122695536(-) A-I      intronic chr12:122699541(-) A-I      intronic chr12:122704566(-) A-I      intronic chr12:122695526(-) A-I      intronic chr12:122697833(-) A-I      intronic chr12:122699210(-) A-I      intronic chr12:122697336(-) A-I      intronic chr12:122699433(-) A-I      intronic chr12:122698044(-) A-I      intronic chr12:122704766(-) A-I      intronic chr12:122697710(-) A-I      intronic chr12:122699155(-) A-I      intronic chr12:122708522(-) A-I      intronic chr12:122698546(-) A-I      intronic chr12:122693725(-) A-I      intronic chr12:122693827(-) A-I      intronic chr12:122708476(-) A-I      intronic chr12:122702224(-) A-I      intronic chr12:122704691(-) A-I      intronic chr12:122702140(-) A-I      intronic chr12:122699630(-) A-I      intronic chr12:122706114(-) A-I      intronic chr12:122697201(-) A-I      intronic chr12:122695487(-) A-I      intronic chr12:122699742(-) A-I      intronic chr12:122702280(-) A-I      intronic chr12:122695207(-) A-I      intronic chr12:122704619(-) A-I      intronic chr12:122700068(-) A-I      intronic chr12:122696005(-) A-I      intronic chr12:122709612(-) A-I      5'UTR chr12:122707799(-) A-I      intronic chr12:122699746(-) A-I      intronic chr12:122699360(-) A-I      intronic chr12:122695099(-) A-I      intronic chr12:122702164(-) A-I      intronic chr12:122700366(-) A-I      intronic chr12:122699826(-) A-I      intronic chr12:122699729(-) A-I      intronic chr12:122704720(-) A-I      intronic chr12:122696091(-) A-I      intronic chr12:122700363(-) A-I      intronic chr12:122699127(-) A-I      intronic chr12:122695940(-) A-I      intronic chr12:122706039(-) A-I      intronic chr12:122698545(-) A-I      intronic chr12:122704606(-) A-I      intronic chr12:122695463(-) A-I      intronic chr12:122698387(-) A-I      intronic chr12:122702257(-) A-I      intronic chr12:122705036(-) A-I      intronic chr12:122699166(-) A-I      intronic chr12:122699408(-) A-I      intronic chr12:122695475(-) A-I      intronic chr12:122700003(-) A-I      intronic chr12:122700104(-) A-I      intronic chr12:122698599(-) A-I      intronic chr12:122699150(-) A-I      intronic chr12:122707819(-) A-I      intronic chr12:122706110(-) A-I      intronic chr12:122694149(-) A-I      intronic chr12:122699766(-) A-I      intronic chr12:122704288(-) A-I      intronic chr12:122706171(-) A-I      intronic chr12:122695883(-) A-I      intronic chr12:122701894(-) A-I      intronic chr12:122699015(-) A-I      intronic chr12:122696148(-) A-I      intronic chr12:122702185(-) A-I      intronic chr12:122699176(-) A-I      intronic chr12:122706152(-) A-I      intronic chr12:122705010(-) A-I      intronic chr12:122707898(-) A-I      intronic chr12:122699682(-) A-I      intronic chr12:122699111(-) A-I      intronic chr12:122700051(-) A-I      intronic chr12:122704341(-) A-I      intronic chr12:122695478(-) A-I      intronic chr12:122697583(-) A-I      intronic chr12:122699869(-) A-I      intronic chr12:122704159(-) A-I      intronic chr12:122704587(-) A-I      intronic chr12:122706010(-) A-I      intronic chr12:122696222(-) A-I      intronic chr12:122699273(-) A-I      intronic chr12:122702340(-) A-I      intronic chr12:122699292(-) A-I      intronic chr12:122699002(-) A-I      intronic chr12:122708526(-) A-I      intronic chr12:122697310(-) A-I      intronic chr12:122699464(-) A-I      intronic chr12:122696662(-) A-I      intronic chr12:122693720(-) A-I      intronic chr12:122702363(-) A-I      intronic chr12:122695520(-) A-I      intronic chr12:122702287(-) A-I      intronic chr12:122697954(-) A-I      intronic chr12:122695198(-) A-I      intronic chr12:122701868(-) A-I      intronic chr12:122695058(-) A-I      intronic chr12:122699271(-) A-I      intronic chr12:122708378(-) A-I      intronic chr12:122696189(-) A-I      intronic chr12:122701962(-) A-I      intronic chr12:122704298(-) A-I      intronic chr12:122704145(-) A-I      intronic chr12:122704730(-) A-I      intronic chr12:122697632(-) A-I      intronic chr12:122706144(-) A-I      intronic chr12:122706148(-) A-I      intronic chr12:122694042(-) A-I      intronic chr12:122706127(-) A-I      intronic chr12:122700386(-) A-I      intronic chr12:122705988(-) A-I      intronic chr12:122699219(-) A-I      intronic chr12:122700373(-) A-I      intronic chr12:122707028(-) A-I      intronic chr12:122707765(-) A-I      intronic chr12:122699081(-) A-I      intronic chr12:122699691(-) A-I      intronic chr12:122699206(-) A-I      intronic chr12:122695743(-) A-I      intronic chr12:122702190(-) A-I      intronic chr12:122697502(-) A-I      intronic chr12:122708377(-) A-I      intronic chr12:122699451(-) A-I      intronic chr12:122698016(-) A-I      intronic chr12:122697977(-) A-I      intronic chr12:122706218(-) A-I      intronic chr12:122702347(-) A-I      intronic chr12:122706188(-) A-I      intronic chr12:122706088(-) A-I      intronic chr12:122701979(-) A-I      intronic chr12:122695781(-) A-I      intronic chr12:122699291(-) A-I      intronic chr12:122697606(-) A-I      intronic chr12:122702200(-) A-I      intronic chr12:122698029(-) A-I      intronic chr12:122697515(-) A-I      intronic chr12:122695827(-) A-I      intronic chr12:122699676(-) A-I      intronic chr12:122697707(-) A-I      intronic chr12:122708517(-) A-I      intronic chr12:122694992(-) A-I      intronic chr12:122708486(-) A-I      intronic chr12:122699690(-) A-I      intronic chr12:122704602(-) A-I      intronic chr12:122697688(-) A-I      intronic chr12:122695767(-) A-I      intronic chr12:122698375(-) A-I      intronic chr12:122702318(-) A-I      intronic chr12:122702159(-) A-I      intronic chr12:122699174(-) A-I      intronic chr12:122699402(-) A-I      intronic chr12:122695465(-) A-I      intronic chr12:122699214(-) A-I      intronic chr12:122709034(-) A-I      intronic chr12:122696038(-) A-I      intronic chr12:122699411(-) A-I      intronic chr12:122698549(-) A-I      intronic chr12:122703232(-) A-I      intronic chr12:122693650(-) A-I      intronic chr12:122697209(-) A-I      intronic chr12:122708555(-) A-I      intronic chr12:122701809(-) A-I      intronic chr12:122697985(-) A-I      intronic chr12:122706968(-) A-I      intronic chr12:122696669(-) A-I      intronic chr12:122707816(-) A-I      intronic chr12:122699711(-) A-I      intronic chr12:122704147(-) A-I      intronic chr12:122704628(-) A-I      intronic chr12:122698839(-) A-I      intronic chr12:122704772(-) A-I      intronic chr12:122701867(-) A-I      intronic chr12:122697431(-) A-I      intronic chr12:122701940(-) A-I      intronic chr12:122695712(-) A-I      intronic chr12:122704580(-) A-I      intronic chr12:122699988(-) A-I      intronic chr12:122707282(-) A-I      intronic chr12:122702341(-) A-I      intronic chr12:122698830(-) A-I      intronic chr12:122706982(-) A-I      intronic chr12:122695849(-) A-I      intronic chr12:122708546(-) A-I      intronic chr12:122705158(-) A-I      intronic chr12:122704760(-) A-I      intronic chr12:122696639(-) A-I      intronic chr12:122695429(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	DIABLO	chr12:122701825(-) A-I intron -    15258596 chr12:122701867(-) A-I intron -    15258596 chr12:122701868(-) A-I intron -    15258596 chr12:122696669(-) A-I intron -    21960545 chr12:122695044(-) A-G intron -    22484847 chr12:122695058(-) A-G intron -    22484847 chr12:122695463(-) A-G intron -    22484847 chr12:122695475(-) A-G intron -    22484847 chr12:122695478(-) A-G intron -    22484847 chr12:122696005(-) A-G intron -    22484847 chr12:122696091(-) A-G intron -    22484847 chr12:122696658(-) A-G intron -    22484847 chr12:122696669(-) A-G intron -    22484847 chr12:122697201(-) A-G intron -    22484847 chr12:122697707(-) A-G intron -    22484847 chr12:122698387(-) A-G intron -    22484847 chr12:122700373(-) A-G intron -    22484847 chr12:122706144(-) A-G intron -    22484847 chr12:122706152(-) A-G intron -    22484847 chr12:122706171(-) A-G intron -    22484847 chr12:122706188(-) A-G intron -    22484847 chr12:122694214(-) G-T intron -    22484847 chr12:122695198(-) A-G intron -    22484847 chr12:122695423(-) A-G intron -    22484847 chr12:122695429(-) A-G intron -    22484847 chr12:122695465(-) A-G intron -    22484847 chr12:122695520(-) A-G intron -    22484847 chr12:122695526(-) A-G intron -    22484847 chr12:122695712(-) A-G intron -    22484847 chr12:122695767(-) A-G intron -    22484847 chr12:122695940(-) A-G intron -    22484847 chr12:122696189(-) A-G intron -    22484847 chr12:122696222(-) A-G intron -    22484847 chr12:122697431(-) A-G intron -    22484847 chr12:122697502(-) A-G intron -    22484847 chr12:122698016(-) A-G intron -    22484847 chr12:122698029(-) A-G intron -    22484847 chr12:122698037(-) A-G intron -    22484847 chr12:122698044(-) A-G intron -    22484847 chr12:122698375(-) A-G intron -    22484847 chr12:122698545(-) A-G intron -    22484847 chr12:122698546(-) A-G intron -    22484847 chr12:122698830(-) A-G intron -    22484847 chr12:122699111(-) A-G intron -    22484847 chr12:122699127(-) A-G intron -    22484847 chr12:122699219(-) A-G intron -    22484847 chr12:122699292(-) A-G intron -    22484847 chr12:122699392(-) A-G intron -    22484847 chr12:122699407(-) A-G intron -    22484847 chr12:122699408(-) A-G intron -    22484847 chr12:122699527(-) A-G intron -    22484847 chr12:122699541(-) A-G intron -    22484847 chr12:122699746(-) A-G intron -    22484847 chr12:122699766(-) A-G intron -    22484847 chr12:122700051(-) A-G intron -    22484847 chr12:122700366(-) A-G intron -    22484847 chr12:122701809(-) A-G intron -    22484847 chr12:122701867(-) A-G intron -    22484847 chr12:122701868(-) A-G intron -    22484847 chr12:122701940(-) A-G intron -    22484847 chr12:122701962(-) A-G intron -    22484847 chr12:122701979(-) A-G intron -    22484847 chr12:122702159(-) A-G intron -    22484847 chr12:122702164(-) A-G intron -    22484847 chr12:122702224(-) A-G intron -    22484847 chr12:122702276(-) A-G intron -    22484847 chr12:122702287(-) A-G intron -    22484847 chr12:122702347(-) A-G intron -    22484847 chr12:122702363(-) A-G intron -    22484847 chr12:122704145(-) A-G intron -    22484847 chr12:122704147(-) A-G intron -    22484847 chr12:122704288(-) A-G intron -    22484847 chr12:122704298(-) A-G intron -    22484847 chr12:122704619(-) A-G intron -    22484847 chr12:122704628(-) A-G intron -    22484847 chr12:122704691(-) A-G intron -    22484847 chr12:122704720(-) A-G intron -    22484847 chr12:122704760(-) A-G intron -    22484847 chr12:122704766(-) A-G intron -    22484847 chr12:122704772(-) A-G intron -    22484847 chr12:122705010(-) A-G intron -    22484847 chr12:122706088(-) A-G intron -    22484847 chr12:122706960(-) A-G intron -    22484847 chr12:122706968(-) A-G intron -    22484847 chr12:122706982(-) A-G intron -    22484847 chr12:122707028(-) A-G intron -    22484847 chr12:122707765(-) A-G intron -    22484847 chr12:122708378(-) A-G intron -    22484847 chr12:122708455(-) A-G intron -    22484847 chr12:122708486(-) A-G intron -    22484847 chr12:122708522(-) A-G intron -    22484847 chr12:122708546(-) A-G intron -    22484847 chr12:122709774(-) C-T intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	DIABLO	chr12:122692325-122692326(-) m6A 3'UTR       24284625//24981863//27773535//22608085 chr12:122692341-122692342(-) m6A 3'UTR       24284625//24981863//27773535//22608085 chr12:122692396-122692397(-) m6A 3'UTR       24284625//24981863 chr12:122692420-122692421(-) m6A 3'UTR       24284625 chr12:122692495-122692496(-) m6A 3'UTR       24284625 chr12:122692745-122692746(-) m6A 3'UTR       24284625//25456834//24981863//28052920//27773535//27371828//22575960//22608085 chr12:122692989-122692990(-) m6A 3'UTR//CDS       25456834//24981863//28052920//26404942//27773535//27371828//27773536 chr12:122693013-122693014(-) Cm 3'UTR//CDS       - chr12:122693031-122693032(-) m6A 3'UTR//CDS       24981863//28052920//27773535//27371828//27773536 chr12:122693074-122693075(-) m6A 3'UTR//CDS       24981863//27773535//27371828 chr12:122701037-122701038(-) m6A 3'UTR//CDS//exon       24981863//27773535//27371828 chr12:122710187-122710188(-) m6A 5'UTR//intron       25456834//24981863//27371828//27773536 chr12:122710278-122710279(-) m6A 5'UTR//intron       27773536 chr12:122710355-122710356(-) m6A 5'UTR//intron       27773536 chr12:122710362-122710363(-) m6A 5'UTR//intron       27773536 chr12:122710457-122710458(-) m6A 5'UTR//intron       24981863 chr12:122710467-122710468(-) m6A 5'UTR//intron       24981863 chr12:122710480-122710481(-) m6A 5'UTR//intron       24981863 chr12:122710485-122710486(-) m6A 5'UTR//intron       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-1294	Exosome Plasma     23663360 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Serum     24797360 Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
	DIABLO	Chromatin K562 cells     - Exosome Blood     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-1294
Interactor2: DIABLO

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.