Detail Information

Basic Information:


  VIRBase ID:  

HHID00069647

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-1294:           CDCA4:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-1294 CDCA4
miRBase
Accession/Entrez ID		 MIMAT0005884 55038
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - HEPP//SEI-3/HEPP

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-1294
rs1162939290 chr5:154347163    G/T
rs1179835339 chr5:154347171    G/GTATA
rs1237976003 chr5:154347166    T/C
rs1255234532 chr5:154347174    T/A
rs1465013068 chr5:154347169    T/C
rs189565536 chr5:154347168    G/T
rs1211754242 chr5:154347158    G/A
rs1341512450 chr5:154347155    T/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR CDCA4
chr14:105483264(-) A-I      intronic
chr14:105484033(-) A-I      intronic
chr14:105486215(-) A-I      intronic
chr14:105484028(-) A-I      intronic
chr14:105484020(-) A-I      intronic
chr14:105484081(-) A-I      intronic
chr14:105483764(-) A-I      intronic
chr14:105483698(-) A-I      intronic
chr14:105484004(-) A-I      intronic
chr14:105483987(-) A-I      intronic
chr14:105483934(-) A-I      intronic
chr14:105483724(-) A-I      intronic
chr14:105483834(-) A-I      intronic
chr14:105483734(-) A-I      intronic
chr14:105484082(-) A-I      intronic
chr14:105484121(-) A-I      intronic
chr14:105484085(-) A-I      intronic
chr14:105484092(-) A-I      intronic
chr14:105483670(-) A-I      intronic
chr14:105483642(-) A-I      intronic
chr14:105483738(-) A-I      intronic
chr14:105483754(-) A-I      intronic
chr14:105483052(-) A-I      intronic
chr14:105480482(-) A-I      intronic
chr14:105483130(-) A-I      intronic
chr14:105483371(-) A-I      intronic
chr14:105480446(-) A-I      intronic
chr14:105485212(-) A-I      intronic
chr14:105483833(-) A-I      intronic
chr14:105483697(-) A-I      intronic
chr14:105483740(-) A-I      intronic
chr14:105484046(-) A-I      intronic
chr14:105483366(-) A-I      intronic
chr14:105483033(-) A-I      intronic
chr14:105484505(-) A-I      intronic
chr14:105480322(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED CDCA4
chr14:105483130(-) A-I intron -    22327324
chr14:105483033(-) A-I intron -    21960545
chr14:105483052(-) A-I intron -    21960545
chr14:105480322(-) A-G intron -    22484847
chr14:105483130(-) A-G intron -    22484847
chr14:105483754(-) A-G intron -    22484847
chr14:105480482(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase CDCA4
chr14:105476277-105476278(-) m6A 3'UTR       27773535
chr14:105476307-105476308(-) m6A 3'UTR       27773535
chr14:105476436-105476437(-) Y 3'UTR       26075521
chr14:105476827-105476828(-) m6A 3'UTR       -
chr14:105476871-105476872(-) m6A 3'UTR       -
chr14:105477057-105477058(-) m6A 3'UTR//intron       24981863
chr14:105477080-105477081(-) m6A 3'UTR//intron       24981863
chr14:105477410-105477411(-) m6A 3'UTR//intron       24284625//25456834//24981863//27371828//27773536//22575960//22608085
chr14:105477545-105477546(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27371828//27773536//22575960//22608085
chr14:105477571-105477572(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27371828//27773536//22575960//22608085
chr14:105477691-105477692(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085
chr14:105477712-105477713(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085
chr14:105477748-105477749(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085
chr14:105477755-105477756(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085
chr14:105477805-105477806(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085
chr14:105478150-105478151(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27371828//27773536//22575960//22608085
chr14:105478190-105478191(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27371828//27773536//22575960//22608085
chr14:105478251-105478252(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27371828//27773536//22575960//22608085
chr14:105487360-105487361(-) m6A 5'UTR       24284625//24209618//25456834//24981863//27371828//27773536//22575960//22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-1294
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Serum     24797360
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
CDCA4
Chromatin K562 cells     -
Exosome Blood     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-1294
Interactor2: CDCA4

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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