Detail Information

Basic Information:


  VIRBase ID:  

HHID00069634

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-1294:           LANCL1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-1294 LANCL1
miRBase
Accession/Entrez ID		 MIMAT0005884 10314
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - GPR69A//p40

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-1294
rs1162939290 chr5:154347163    G/T
rs1179835339 chr5:154347171    G/GTATA
rs1237976003 chr5:154347166    T/C
rs1255234532 chr5:154347174    T/A
rs1465013068 chr5:154347169    T/C
rs189565536 chr5:154347168    G/T
rs1211754242 chr5:154347158    G/A
rs1341512450 chr5:154347155    T/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR LANCL1
chr2:211340188(-) A-I      intronic
chr2:211337870(-) A-I      intronic
chr2:211337854(-) A-I      intronic
chr2:211337937(-) A-I      intronic
chr2:211340303(-) A-I      intronic
chr2:211340148(-) A-I      intronic
chr2:211340260(-) A-I      intronic
chr2:211337975(-) A-I      intronic
chr2:211339406(-) A-I      intronic
chr2:211337934(-) A-I      intronic
chr2:211340256(-) A-I      intronic
chr2:211339357(-) A-I      intronic
chr2:211337977(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED LANCL1
chr2:211339357(-) A-G intron -    22484847
chr2:211339387(-) A-G intron -    22484847
chr2:211339406(-) A-G intron -    22484847
chr2:211340290(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase LANCL1
chr2:211298859-211298860(-) m6A 3'UTR       27773535
chr2:211298929-211298930(-) m6A 3'UTR       27773535
chr2:211299103-211299104(-) m6A 3'UTR       24284625//24981863//27773535//22575960//22608085
chr2:211299110-211299111(-) m6A 3'UTR       24284625//24981863//27773535//22575960//22608085
chr2:211299122-211299123(-) m6A 3'UTR       24284625//24981863//27773535//22575960//22608085
chr2:211299157-211299158(-) m6A 3'UTR       24284625//24981863//27773535//22575960//22608085
chr2:211299216-211299217(-) m6A CDS       24284625//24981863//27773535//22575960//22608085
chr2:211299275-211299276(-) m6A CDS       24284625//24981863//22575960
chr2:211300133-211300134(-) m6A CDS       24284625
chr2:211300140-211300141(-) m6A CDS       24284625
chr2:211300153-211300154(-) m6A CDS       24284625
chr2:211341260-211341261(-) m6A 5'UTR//intron       24981863
chr2:211341489-211341490(-) m6A 5'UTR//intron       25456834//24981863
chr2:211342217-211342218(-) m6A 5'UTR       24981863
chr2:211342263-211342264(-) m6A 5'UTR       24981863
chr2:211342276-211342277(-) m6A 5'UTR       24981863
chr2:211342310-211342311(-) m6A 5'UTR       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-1294
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Serum     24797360
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
LANCL1
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol K562 cells     -
Exosome Blood     -
Nucleus HCC cell line (HepG2)     -
Ribosome HEK-293 cells     22199352
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-1294
Interactor2: LANCL1

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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