Detail Information

Basic Information:


  VIRBase ID:  

HHID00069632

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-1294:           TOMM70:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-1294 TOMM70
miRBase
Accession/Entrez ID		 MIMAT0005884 9868
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - Tom70//TOMM70A

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-1294
rs1162939290 chr5:154347163    G/T
rs1179835339 chr5:154347171    G/GTATA
rs1237976003 chr5:154347166    T/C
rs1255234532 chr5:154347174    T/A
rs1465013068 chr5:154347169    T/C
rs189565536 chr5:154347168    G/T
rs1211754242 chr5:154347158    G/A
rs1341512450 chr5:154347155    T/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR TOMM70
chr3:100113602(-) A-I      intronic
chr3:100113593(-) A-I      intronic
chr3:100098410(-) A-I      intronic
chr3:100106285(-) A-I      intronic
chr3:100108822(-) A-I      intronic
chr3:100111292(-) A-I      intronic
chr3:100111322(-) A-I      intronic
chr3:100114024(-) A-I      intronic
chr3:100098558(-) A-I      intronic
chr3:100106215(-) A-I      intronic
chr3:100098690(-) A-I      intronic
chr3:100114166(-) A-I      intronic
chr3:100114065(-) A-I      intronic
chr3:100111436(-) A-I      intronic
chr3:100098705(-) A-I      intronic
chr3:100098729(-) A-I      intronic
chr3:100111362(-) A-I      intronic
chr3:100106172(-) A-I      intronic
chr3:100106179(-) A-I      intronic
chr3:100111438(-) A-I      intronic
chr3:100106198(-) A-I      intronic
chr3:100111439(-) A-I      intronic
chr3:100113529(-) A-I      intronic
chr3:100106208(-) A-I      intronic
chr3:100106209(-) A-I      intronic
chr3:100098348(-) A-I      intronic
chr3:100111548(-) A-I      intronic
chr3:100111494(-) A-I      intronic
chr3:100085898(-) A-I      intronic
chr3:100098360(-) A-I      intronic
chr3:100098420(-) A-I      intronic
chr3:100098625(-) A-I      intronic
chr3:100111855(-) A-I      intronic
chr3:100098945(-) A-I      intronic
chr3:100106683(-) A-I      intronic
chr3:100113566(-) A-I      intronic
chr3:100098946(-) A-I      intronic
chr3:100113620(-) A-I      intronic
chr3:100113963(-) A-I      intronic
chr3:100114199(-) A-I      intronic
chr3:100111384(-) A-I      intronic
chr3:100109468(-) A-I      intronic
chr3:100098526(-) A-I      intronic
chr3:100099065(-) A-I      intronic
chr3:100114300(-) A-I      intronic
chr3:100111442(-) A-I      intronic
chr3:100098552(-) A-I      intronic
chr3:100098347(-) A-I      intronic
chr3:100113619(-) A-I      intronic
chr3:100114304(-) A-I      intronic
chr3:100113524(-) A-I      intronic
chr3:100098599(-) A-I      intronic
chr3:100106205(-) A-I      intronic
chr3:100085921(-) A-I      intronic
chr3:100106151(-) A-I      intronic

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-1294
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Serum     24797360
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
TOMM70
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol K562 cells     -
Exosome Blood     -
Membrane HCC cell line (HepG2)     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus Colon cancer cells     24393600
Nucleus K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-1294
Interactor2: TOMM70

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region CDS
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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