Basic Information:

  VIRBase ID:  

HHID00069630

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-1294:  MIMAT0005884          MFHAS1:  NM_004225     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-1294	MFHAS1
miRBase Accession/Entrez ID	MIMAT0005884	9258
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	LRRC65//MASL1//ROCO4

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-1294	rs1162939290 chr5:154347163    G/T rs1179835339 chr5:154347171    G/GTATA rs1237976003 chr5:154347166    T/C rs1255234532 chr5:154347174    T/A rs1465013068 chr5:154347169    T/C rs189565536 chr5:154347168    G/T rs1211754242 chr5:154347158    G/A rs1341512450 chr5:154347155    T/G

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	MFHAS1	chr8:8744529(-) A-I      intronic chr8:8724024(-) A-I      intronic chr8:8742449(-) A-I      intronic chr8:8644769(-) A-I      intronic chr8:8644770(-) A-I      intronic chr8:8644869(-) A-I      intronic chr8:8646142(-) A-I      intronic chr8:8646143(-) A-I      intronic chr8:8646145(-) A-I      intronic chr8:8646183(-) A-I      intronic chr8:8649854(-) A-I      intronic chr8:8655938(-) A-I      intronic chr8:8663345(-) A-I      intronic chr8:8663372(-) A-I      intronic chr8:8677015(-) A-I      intronic chr8:8677028(-) A-I      intronic chr8:8682752(-) A-I      intronic chr8:8682853(-) A-I      intronic chr8:8684121(-) A-I      intronic chr8:8684131(-) A-I      intronic chr8:8742218(-) A-I      intronic chr8:8684134(-) A-I      intronic chr8:8738332(-) A-I      intronic chr8:8738303(-) A-I      intronic chr8:8738297(-) A-I      intronic chr8:8738287(-) A-I      intronic chr8:8736740(-) A-I      intronic chr8:8736696(-) A-I      intronic chr8:8736656(-) A-I      intronic chr8:8734361(-) A-I      intronic chr8:8734107(-) A-I      intronic chr8:8734097(-) A-I      intronic chr8:8724001(-) A-I      intronic chr8:8723997(-) A-I      intronic chr8:8723996(-) A-I      intronic chr8:8716823(-) A-I      intronic chr8:8715268(-) A-I      intronic chr8:8715239(-) A-I      intronic chr8:8715122(-) A-I      intronic chr8:8715111(-) A-I      intronic chr8:8712730(-) A-I      intronic chr8:8738286(-) A-I      intronic chr8:8706855(-) A-I      intronic chr8:8706847(-) A-I      intronic chr8:8706798(-) A-I      intronic chr8:8706787(-) A-I      intronic chr8:8686973(-) A-I      intronic chr8:8706786(-) A-I      intronic chr8:8706784(-) A-I      intronic chr8:8686974(-) A-I      intronic chr8:8687189(-) A-I      intronic chr8:8689215(-) A-I      intronic chr8:8689216(-) A-I      intronic chr8:8706770(-) A-I      intronic chr8:8706769(-) A-I      intronic chr8:8706761(-) A-I      intronic chr8:8733285(-) A-I      intronic chr8:8689312(-) A-I      intronic chr8:8693986(-) A-I      intronic chr8:8728903(-) A-I      intronic chr8:8728483(-) A-I      intronic chr8:8694058(-) A-I      intronic chr8:8694100(-) A-I      intronic chr8:8694115(-) A-I      intronic chr8:8695067(-) A-I      intronic chr8:8712509(-) A-I      intronic chr8:8698817(-) A-I      intronic chr8:8711838(-) A-I      intronic chr8:8698822(-) A-I      intronic chr8:8698866(-) A-I      intronic chr8:8698873(-) A-I      intronic chr8:8698952(-) A-I      intronic chr8:8699734(-) A-I      intronic chr8:8699824(-) A-I      intronic chr8:8699833(-) A-I      intronic chr8:8711270(-) A-I      intronic chr8:8711258(-) A-I      intronic chr8:8711254(-) A-I      intronic chr8:8711252(-) A-I      intronic chr8:8711215(-) A-I      intronic chr8:8711214(-) A-I      intronic chr8:8711201(-) A-I      intronic chr8:8711153(-) A-I      intronic chr8:8711142(-) A-I      intronic chr8:8709840(-) A-I      intronic chr8:8708196(-) A-I      intronic chr8:8699927(-) A-I      intronic chr8:8703680(-) A-I      intronic chr8:8706680(-) A-I      intronic chr8:8706699(-) A-I      intronic chr8:8706702(-) A-I      intronic chr8:8706863(-) A-I      intronic chr8:8706864(-) A-I      intronic chr8:8708095(-) A-I      intronic chr8:8711221(-) A-I      intronic chr8:8739703(-) A-I      intronic chr8:8711864(-) A-I      intronic chr8:8712735(-) A-I      intronic chr8:8711322(-) A-I      intronic chr8:8704719(-) A-I      intronic chr8:8708109(-) A-I      intronic chr8:8743791(-) A-I      intronic chr8:8712512(-) A-I      intronic chr8:8740010(-) A-I      intronic chr8:8744554(-) A-I      intronic chr8:8712695(-) A-I      intronic chr8:8690204(-) A-I      intronic chr8:8743401(-) A-I      intronic chr8:8711109(-) A-I      intronic chr8:8741489(-) A-I      intronic chr8:8689344(-) A-I      intronic chr8:8695070(-) A-I      intronic chr8:8706707(-) A-I      intronic chr8:8733212(-) A-I      intronic chr8:8742365(-) A-I      intronic chr8:8712148(-) A-I      intronic chr8:8709901(-) A-I      intronic chr8:8708252(-) A-I      intronic chr8:8733269(-) A-I      intronic chr8:8684191(-) A-I      intronic chr8:8711752(-) A-I      intronic chr8:8712522(-) A-I      intronic chr8:8712517(-) A-I      intronic chr8:8712109(-) A-I      intronic chr8:8649940(-) A-I      intronic chr8:8688181(-) A-I      intronic chr8:8742287(-) A-I      intronic chr8:8734565(-) A-I      intronic chr8:8709872(-) A-I      intronic chr8:8734349(-) A-I      intronic chr8:8703600(-) A-I      intronic chr8:8706837(-) A-I      intronic chr8:8706833(-) A-I      intronic chr8:8711867(-) A-I      intronic chr8:8689301(-) A-I      intronic chr8:8698819(-) A-I      intronic chr8:8743924(-) A-I      intronic chr8:8663442(-) A-I      intronic chr8:8711993(-) A-I      intronic chr8:8644862(-) A-I      intronic chr8:8728506(-) A-I      intronic chr8:8739634(-) A-I      intronic chr8:8712073(-) A-I      intronic chr8:8738363(-) A-I      intronic chr8:8649860(-) A-I      intronic chr8:8706760(-) A-I      intronic chr8:8723967(-) A-I      intronic chr8:8738364(-) A-I      intronic chr8:8670292(-) A-I      intronic chr8:8738377(-) A-I      intronic chr8:8711182(-) A-I      intronic chr8:8733265(-) A-I      intronic chr8:8698863(-) A-I      intronic chr8:8706755(-) A-I      intronic chr8:8656315(-) A-I      intronic chr8:8695071(-) A-I      intronic chr8:8738374(-) A-I      intronic chr8:8689311(-) A-I      intronic chr8:8716732(-) A-I      intronic chr8:8677051(-) A-I      intronic chr8:8656308(-) A-I      intronic chr8:8699860(-) A-I      intronic chr8:8698885(-) A-I      intronic chr8:8690277(-) A-I      intronic chr8:8688155(-) A-I      intronic chr8:8711192(-) A-I      intronic chr8:8744474(-) A-I      intronic chr8:8722704(-) A-I      intronic chr8:8711279(-) A-I      intronic chr8:8682755(-) A-I      intronic chr8:8725340(-) A-I      intronic chr8:8738432(-) A-I      intronic chr8:8711253(-) A-I      intronic chr8:8733369(-) A-I      intronic chr8:8724003(-) A-I      intronic chr8:8682962(-) A-I      intronic chr8:8706759(-) A-I      intronic chr8:8744525(-) A-I      intronic chr8:8712112(-) A-I      intronic chr8:8708272(-) A-I      intronic chr8:8689283(-) A-I      intronic chr8:8690200(-) A-I      intronic chr8:8706850(-) A-I      intronic chr8:8742312(-) A-I      intronic chr8:8664349(-) A-I      intronic chr8:8687091(-) A-I      intronic chr8:8711724(-) A-I      intronic chr8:8663376(-) A-I      intronic chr8:8734764(-) A-I      intronic chr8:8706870(-) A-I      intronic chr8:8684031(-) A-I      intronic chr8:8706758(-) A-I      intronic chr8:8706794(-) A-I      intronic chr8:8733238(-) A-I      intronic chr8:8711741(-) A-I      intronic chr8:8655898(-) A-I      intronic chr8:8667719(-) A-I      intronic chr8:8743804(-) A-I      intronic chr8:8738399(-) A-I      intronic chr8:8703597(-) A-I      intronic chr8:8698734(-) A-I      intronic chr8:8691553(-) A-I      intronic chr8:8711873(-) A-I      intronic chr8:8686999(-) A-I      intronic chr8:8743928(-) A-I      intronic chr8:8708177(-) A-I      intronic chr8:8716771(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	MFHAS1	chr8:8663376(-) A-G intron -    22484847 chr8:8663442(-) A-G intron -    22484847 chr8:8682755(-) A-G intron -    22484847 chr8:8682820(-) A-G intron -    22484847 chr8:8682962(-) A-G intron -    22484847 chr8:8684191(-) A-G intron -    22484847 chr8:8686999(-) A-G intron -    22484847 chr8:8687091(-) A-G intron -    22484847 chr8:8690918(-) G-A intron -    22484847 chr8:8695070(-) A-G intron -    22484847 chr8:8695071(-) A-G intron -    22484847 chr8:8697801(-) A-G intron -    22484847 chr8:8697804(-) A-G intron -    22484847 chr8:8698819(-) A-G intron -    22484847 chr8:8698863(-) A-G intron -    22484847 chr8:8698885(-) A-G intron -    22484847 chr8:8698940(-) A-G intron -    22484847 chr8:8699820(-) A-G intron -    22484847 chr8:8706755(-) A-G intron -    22484847 chr8:8706758(-) A-G intron -    22484847 chr8:8706759(-) A-G intron -    22484847 chr8:8706760(-) A-G intron -    22484847 chr8:8706850(-) A-G intron -    22484847 chr8:8706870(-) A-G intron -    22484847 chr8:8708182(-) A-G intron -    22484847 chr8:8708252(-) A-G intron -    22484847 chr8:8709872(-) A-G intron -    22484847 chr8:8709901(-) A-G intron -    22484847 chr8:8711221(-) A-G intron -    22484847 chr8:8711237(-) A-G intron -    22484847 chr8:8711255(-) A-G intron -    22484847 chr8:8711275(-) A-G intron -    22484847 chr8:8711279(-) A-G intron -    22484847 chr8:8711322(-) A-G intron -    22484847 chr8:8711752(-) A-G intron -    22484847 chr8:8711842(-) A-G intron -    22484847 chr8:8711864(-) A-G intron -    22484847 chr8:8711873(-) A-G intron -    22484847 chr8:8711993(-) A-G intron -    22484847 chr8:8712073(-) A-G intron -    22484847 chr8:8712109(-) A-G intron -    22484847 chr8:8712119(-) A-G intron -    22484847 chr8:8712138(-) A-G intron -    22484847 chr8:8712148(-) A-G intron -    22484847 chr8:8712149(-) A-G intron -    22484847 chr8:8712512(-) A-G intron -    22484847 chr8:8712517(-) A-G intron -    22484847 chr8:8712522(-) A-G intron -    22484847 chr8:8713290(-) A-G intron -    22484847 chr8:8723993(-) A-G intron -    22484847 chr8:8728506(-) A-G intron -    22484847 chr8:8728516(-) A-G intron -    22484847 chr8:8733212(-) A-G intron -    22484847 chr8:8733225(-) A-G intron -    22484847 chr8:8733238(-) A-G intron -    22484847 chr8:8733265(-) A-G intron -    22484847 chr8:8733268(-) A-G intron -    22484847 chr8:8733269(-) A-G intron -    22484847 chr8:8733369(-) A-G intron -    22484847 chr8:8733376(-) A-G intron -    22484847 chr8:8734381(-) A-G intron -    22484847 chr8:8734382(-) A-G intron -    22484847 chr8:8739703(-) A-G intron -    22484847 chr8:8741129(-) T-C intron -    22484847 chr8:8742287(-) A-G intron -    22484847 chr8:8743384(-) A-G intron -    22484847 chr8:8743400(-) A-G intron -    22484847 chr8:8743401(-) A-G intron -    22484847 chr8:8743402(-) A-T intron -    22484847 chr8:8744474(-) A-G intron -    22484847 chr8:8744525(-) A-G intron -    22484847 chr8:8744554(-) A-G intron -    22484847 chr8:8744555(-) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	MFHAS1	chr8:8643301-8643302(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//22608085 chr8:8643309-8643310(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//22608085 chr8:8643336-8643337(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//27371828//22608085 chr8:8643425-8643426(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr8:8643457-8643458(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085 chr8:8643478-8643479(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085 chr8:8643486-8643487(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085 chr8:8643505-8643506(-) Gm 3'UTR//exon       - chr8:8643538-8643539(-) m6A CDS//exon       24284625//24209618//24981863//27773535//27371828//22608085 chr8:8647863-8647864(-) m6A exon//intron       24284625//24209618//27773535//27371828//22608085 chr8:8654978-8654979(-) m6A CDS//exon       24284625//24981863//27773535//27371828//22608085 chr8:8679419-8679420(-) m6A exon//intron       24284625//27773535 chr8:8747643-8747644(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//22575960//22608085 chr8:8747673-8747674(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//22575960//22608085 chr8:8747708-8747709(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//22575960//22608085 chr8:8747752-8747753(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//22575960//22608085 chr8:8747778-8747779(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr8:8747966-8747967(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085 chr8:8748063-8748064(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr8:8748084-8748085(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085 chr8:8748121-8748122(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085 chr8:8748234-8748235(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085 chr8:8748302-8748303(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr8:8748354-8748355(-) Y CDS       26075521 chr8:8748415-8748416(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr8:8748475-8748476(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085 chr8:8748514-8748515(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr8:8748564-8748565(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr8:8748649-8748650(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr8:8748676-8748677(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr8:8748763-8748764(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085 chr8:8748769-8748770(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085 chr8:8748820-8748821(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085 chr8:8748864-8748865(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085 chr8:8748910-8748911(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085 chr8:8748949-8748950(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085 chr8:8749243-8749244(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085 chr8:8749301-8749302(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085 chr8:8749374-8749375(-) m6A CDS       24284625//24209618//25456834//24981863//27371828//27773536//22575960//22608085 chr8:8749447-8749448(-) m6A CDS       24284625//24981863//27371828//22575960//22608085 chr8:8749513-8749514(-) m6A CDS       24284625//22575960//22608085 chr8:8749561-8749562(-) m6A CDS       24284625//22575960 chr8:8749795-8749796(-) m6A CDS       24284625 chr8:8750278-8750279(-) m6A CDS       25456834//24981863//27371828//27773536//22608085 chr8:8750353-8750354(-) m6A CDS       25456834//27371828//27773536//22608085 chr8:8750362-8750363(-) m6A CDS       25456834//27371828//27773536//22608085 chr8:8750377-8750378(-) m6A CDS       25456834//27371828//27773536//22608085 chr8:8750537-8750538(-) m6A CDS       24284625//24209618//25456834//27371828//27773536 chr8:8750554-8750555(-) m6A CDS       24284625//24209618//25456834//27371828//27773536 chr8:8750695-8750696(-) m6A 5'UTR       24209618//27371828 chr8:8751064-8751065(-) m6A 5'UTR       24209618//27773536

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-1294	Exosome Plasma     23663360 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Serum     24797360 Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
	MFHAS1	Chromatin K562 cells     - Exosome Blood     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells|K562 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-1294
Interactor2: MFHAS1

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	CDS
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.