Detail Information

Basic Information:


  VIRBase ID:  

HHID00069426

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-548j-5p:           PIGW:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-548j-5p PIGW
miRBase
Accession/Entrez ID		 MIMAT0005875 284098
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - Gwt1//HPMRS5

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-548j-5p
rs1210209539 chr22:26555275    C/T
rs545900525 chr22:26555280    G/C
rs565141718 chr22:26555283    C/A
rs565141718 chr22:26555283    C/G
rs565141718 chr22:26555283    C/T
rs751780445 chr22:26555284    G/A
rs753744163 chr22:26555282    C/A
rs757533254 chr22:26555285    C/A
rs367750295 chr22:26555290    A/G
rs976434292 chr22:26555292    T/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR PIGW
chr17:34891606(+) A-I      intronic
chr17:34894622(+) A-I      3'UTR
chr17:34894775(+) A-I      3'UTR
chr17:34891605(+) A-I      intronic
chr17:34894878(+) A-I      3'UTR
chr17:34894866(+) A-I      3'UTR

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase PIGW
chr17:34890990-34890991(+) m6A 5'UTR//intron       24209618//25456834//24981863//27371828
chr17:34891087-34891088(+) m6A 5'UTR//intron       24284625//24209618//25456834//24981863//27371828//22608085
chr17:34891219-34891220(+) m6A 5'UTR//intron       24284625//24209618//25456834//24981863//22575960//22608085
chr17:34891246-34891247(+) m6A 5'UTR//intron       24284625//24209618//25456834//24981863//22575960//22608085
chr17:34891408-34891409(+) m6A 5'UTR//intron       24284625//24209618//22608085
chr17:34892998-34892999(+) m6A CDS       24284625//24209618//24981863//22608085
chr17:34893112-34893113(+) m6A CDS       24284625//24209618//24981863//22575960//22608085
chr17:34893253-34893254(+) m6A CDS       24284625//24209618//24981863//22575960//22608085
chr17:34893267-34893268(+) m6A CDS       24284625//24209618//24981863//22575960//22608085
chr17:34893302-34893303(+) m6A CDS       24284625//24209618//24981863//22575960//22608085
chr17:34893392-34893393(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr17:34893424-34893425(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr17:34893439-34893440(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr17:34893551-34893552(+) m6A CDS       24284625//24209618//24981863//22608085
chr17:34893630-34893631(+) m6A CDS       24209618//24981863//22608085
chr17:34893659-34893660(+) m6A CDS       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-548j-5p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
PIGW
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Exosome Blood     -
Nucleolus K562 cells     -
Nucleus Nasopharyngeal carcinoma cells     20498841
Ribosome HEK-293 cells     22199352

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-548j-5p
Interactor2: PIGW

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region CDS
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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