Basic Information:

  VIRBase ID:  

HHID00069425

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-548j-5p:  MIMAT0005875          CNEP1R1:  NR_104042     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-548j-5p	CNEP1R1
miRBase Accession/Entrez ID	MIMAT0005875	255919
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	C16orf69//NEP1-R1//NEP1R1//TMEM188//TMP125

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-548j-5p	rs1210209539 chr22:26555275    C/T rs545900525 chr22:26555280    G/C rs565141718 chr22:26555283    C/A rs565141718 chr22:26555283    C/G rs565141718 chr22:26555283    C/T rs751780445 chr22:26555284    G/A rs753744163 chr22:26555282    C/A rs757533254 chr22:26555285    C/A rs367750295 chr22:26555290    A/G rs976434292 chr22:26555292    T/C

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	CNEP1R1	chr16:50068985(+) A-I      intronic chr16:50066683(+) A-I      intronic chr16:50067687(+) A-I      intronic chr16:50067720(+) A-I      intronic chr16:50067763(+) A-I      intronic chr16:50068768(+) A-I      intronic chr16:50068770(+) A-I      intronic chr16:50066701(+) A-I      intronic chr16:50067740(+) A-I      intronic chr16:50060725(+) A-I      intronic chr16:50069001(+) A-I      intronic chr16:50061499(+) A-I      intronic chr16:50062024(+) A-I      intronic chr16:50066730(+) A-I      intronic chr16:50066734(+) A-I      intronic chr16:50062021(+) A-I      intronic chr16:50066754(+) A-I      intronic chr16:50062133(+) A-I      intronic chr16:50062140(+) A-I      intronic chr16:50067654(+) A-I      intronic chr16:50068653(+) A-I      intronic chr16:50062003(+) A-I      intronic chr16:50061172(+) A-I      intronic chr16:50062061(+) A-I      intronic chr16:50062132(+) A-I      intronic chr16:50062081(+) A-I      intronic chr16:50062055(+) A-I      intronic chr16:50060644(+) A-I      intronic chr16:50060738(+) A-I      intronic chr16:50061298(+) A-I      intronic chr16:50062052(+) A-I      intronic chr16:50061995(+) A-I      intronic chr16:50060796(+) A-I      intronic chr16:50067632(+) A-I      intronic chr16:50061204(+) A-I      intronic chr16:50061943(+) A-I      intronic chr16:50060670(+) A-I      intronic chr16:50061889(+) A-I      intronic chr16:50062008(+) A-I      intronic chr16:50060710(+) A-I      intronic chr16:50068667(+) A-I      intronic chr16:50067520(+) A-I      intronic chr16:50060829(+) A-I      intronic chr16:50061157(+) A-I      intronic chr16:50061565(+) A-I      intronic chr16:50060617(+) A-I      intronic chr16:50062072(+) A-I      intronic chr16:50062034(+) A-I      intronic chr16:50061272(+) A-I      intronic chr16:50061243(+) A-I      intronic chr16:50060721(+) A-I      intronic chr16:50068648(+) A-I      intronic chr16:50067924(+) A-I      intronic chr16:50067519(+) A-I      intronic chr16:50062092(+) A-I      intronic chr16:50060622(+) A-I      intronic chr16:50061449(+) A-I      intronic chr16:50061242(+) A-I      intronic chr16:50061998(+) A-I      intronic chr16:50061899(+) A-I      intronic chr16:50062146(+) A-I      intronic chr16:50068692(+) A-I      intronic chr16:50061494(+) A-I      intronic chr16:50069008(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	CNEP1R1	chr16:50062140(+) A-I intron -    22327324 chr16:50069772(+) A-I intron -    21960545 chr16:50061298(+) A-G intron -    22484847 chr16:50062140(+) A-G intron -    22484847 chr16:50067654(+) A-G intron -    22484847 chr16:50070116(+) C-T intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	CNEP1R1	chr16:50059190-50059191(+) m6A 5'UTR//exon       24981863 chr16:50059230-50059231(+) m6A CDS//exon       24981863 chr16:50069335-50069336(+) m6A 3'UTR//CDS       24981863 chr16:50069347-50069348(+) m6A 3'UTR//CDS       24981863 chr16:50069392-50069393(+) m6A 3'UTR       24981863//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-548j-5p	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Fibroblasts|Mesenchymal stem cells     -
	CNEP1R1	Cytoplasm Nasopharyngeal carcinoma cells     20498841 Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleoplasm K562 cells     - Nucleus Nasopharyngeal carcinoma cells     20498841 Ribosome-free cytosol Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-548j-5p
Interactor2: CNEP1R1

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.