Detail Information

Basic Information:


  VIRBase ID:  

HHID00069398

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-548j-5p:           SLC15A4:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-548j-5p SLC15A4
miRBase
Accession/Entrez ID		 MIMAT0005875 121260
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - FP12591//PHT1//PTR4

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-548j-5p
rs1210209539 chr22:26555275    C/T
rs545900525 chr22:26555280    G/C
rs565141718 chr22:26555283    C/A
rs565141718 chr22:26555283    C/G
rs565141718 chr22:26555283    C/T
rs751780445 chr22:26555284    G/A
rs753744163 chr22:26555282    C/A
rs757533254 chr22:26555285    C/A
rs367750295 chr22:26555290    A/G
rs976434292 chr22:26555292    T/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR SLC15A4
chr12:129289192(-) A-I      intronic
chr12:129291586(-) A-I      intronic
chr12:129291727(-) A-I      intronic
chr12:129300096(-) A-I      intronic
chr12:129290116(-) A-I      intronic
chr12:129290668(-) A-I      intronic
chr12:129291696(-) A-I      intronic
chr12:129300187(-) A-I      intronic
chr12:129290271(-) A-I      intronic
chr12:129300099(-) A-I      intronic
chr12:129291697(-) A-I      intronic
chr12:129291681(-) A-I      intronic
chr12:129300083(-) A-I      intronic
chr12:129291617(-) A-I      intronic
chr12:129290492(-) A-I      intronic
chr12:129290309(-) A-I      intronic
chr12:129290669(-) A-I      intronic
chr12:129290677(-) A-I      intronic
chr12:129291623(-) A-I      intronic
chr12:129289163(-) A-I      intronic
chr12:129300123(-) A-I      intronic
chr12:129289095(-) A-I      intronic
chr12:129300131(-) A-I      intronic
chr12:129290595(-) A-I      intronic
chr12:129291612(-) A-I      intronic
chr12:129289082(-) A-I      intronic
chr12:129290322(-) A-I      intronic
chr12:129290663(-) A-I      intronic
chr12:129299996(-) A-I      intronic
chr12:129300168(-) A-I      intronic
chr12:129290566(-) A-I      intronic
chr12:129307100(-) A-I      intronic
chr12:129291621(-) A-I      intronic
chr12:129300013(-) A-I      intronic
chr12:129289032(-) A-I      intronic
chr12:129307582(-) A-I      intronic
chr12:129290183(-) A-I      intronic
chr12:129300148(-) A-I      intronic
chr12:129290270(-) A-I      intronic
chr12:129300212(-) A-I      intronic
chr12:129290214(-) A-I      intronic
chr12:129307313(-) A-I      intronic
chr12:129291692(-) A-I      intronic
chr12:129290256(-) A-I      intronic
chr12:129291576(-) A-I      intronic
chr12:129289223(-) A-I      intronic
chr12:129290150(-) A-I      intronic
chr12:129307270(-) A-I      intronic
chr12:129290550(-) A-I      intronic
chr12:129290250(-) A-I      intronic
chr12:129301165(-) A-I      intronic
chr12:129307225(-) A-I      intronic
chr12:129307551(-) A-I      intronic
chr12:129300068(-) A-I      intronic
chr12:129289090(-) A-I      intronic
chr12:129290241(-) A-I      intronic
chr12:129290170(-) A-I      intronic
chr12:129289033(-) A-I      intronic
chr12:129290615(-) A-I      intronic
chr12:129291521(-) A-I      intronic
chr12:129289228(-) A-I      intronic
chr12:129290497(-) A-I      intronic
chr12:129300014(-) A-I      intronic
chr12:129301300(-) A-I      intronic
chr12:129290175(-) A-I      intronic
chr12:129291725(-) A-I      intronic
chr12:129290736(-) A-I      intronic
chr12:129300122(-) A-I      intronic
chr12:129307314(-) A-I      intronic
chr12:129290705(-) A-I      intronic
chr12:129307432(-) A-I      intronic
chr12:129290327(-) A-I      intronic
chr12:129291516(-) A-I      intronic
chr12:129307522(-) A-I      intronic
chr12:129307266(-) A-I      intronic
chr12:129289193(-) A-I      intronic
chr12:129290565(-) A-I      intronic
chr12:129290254(-) A-I      intronic
chr12:129301131(-) A-I      intronic
chr12:129290602(-) A-I      intronic
chr12:129307347(-) A-I      intronic
chr12:129307267(-) A-I      intronic
chr12:129307261(-) A-I      intronic
chr12:129307493(-) A-I      intronic
chr12:129291538(-) A-I      intronic
chr12:129290174(-) A-I      intronic
chr12:129291618(-) A-I      intronic
chr12:129307182(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED SLC15A4
chr12:129298759(-) A-I intron -    22327324
chr12:129298779(-) G-A intron -    21725310
chr12:129290241(-) A-G intron -    22484847
chr12:129300013(-) A-G intron -    22484847
chr12:129300168(-) A-G intron -    22484847
chr12:129290736(-) A-G intron -    22484847
chr12:129290174(-) A-G intron -    22484847
chr12:129290175(-) A-G intron -    22484847
chr12:129290188(-) T-G intron -    22484847
chr12:129290270(-) A-G intron -    22484847
chr12:129290327(-) A-G intron -    22484847
chr12:129290565(-) A-G intron -    22484847
chr12:129290615(-) A-G intron -    22484847
chr12:129290708(-) G-T intron -    22484847
chr12:129290709(-) A-T intron -    22484847
chr12:129290710(-) G-T intron -    22484847
chr12:129291692(-) A-G intron -    22484847
chr12:129291725(-) A-G intron -    22484847
chr12:129299996(-) A-G intron -    22484847
chr12:129300014(-) A-G intron -    22484847
chr12:129300068(-) A-G intron -    22484847
chr12:129300212(-) A-G intron -    22484847
chr12:129307313(-) A-G intron -    22484847
chr12:129307314(-) A-G intron -    22484847
chr12:129307582(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase SLC15A4
chr12:129278414-129278415(-) m6A 3'UTR       27773535
chr12:129278446-129278447(-) m6A 3'UTR//exon       27773535
chr12:129278629-129278630(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr12:129278665-129278666(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr12:129278674-129278675(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr12:129278789-129278790(-) m6A 3'UTR//CDS//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr12:129278876-129278877(-) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//27773535
chr12:129283808-129283809(-) m6A 3'UTR//CDS//exon       24284625//24209618//24981863
chr12:129283861-129283862(-) m6A 3'UTR//CDS//exon       24284625//24209618
chr12:129294011-129294012(-) m6A 3'UTR//CDS//exon       -

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-548j-5p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
SLC15A4
Chromatin K562 cells     -
Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-548j-5p
Interactor2: SLC15A4

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region CDS
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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