Basic Information:

  VIRBase ID:  

HHID00069394

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-548j-5p:  MIMAT0005875          FAM114A1:  NM_001350635     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-548j-5p	FAM114A1
miRBase Accession/Entrez ID	MIMAT0005875	92689
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	Noxp20

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-548j-5p	rs1210209539 chr22:26555275    C/T rs545900525 chr22:26555280    G/C rs565141718 chr22:26555283    C/A rs565141718 chr22:26555283    C/G rs565141718 chr22:26555283    C/T rs751780445 chr22:26555284    G/A rs753744163 chr22:26555282    C/A rs757533254 chr22:26555285    C/A rs367750295 chr22:26555290    A/G rs976434292 chr22:26555292    T/C

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	FAM114A1	chr4:38886696(+) A-I      intronic chr4:38886689(+) A-I      intronic chr4:38937897(+) A-I      intronic chr4:38936670(+) A-I      intronic chr4:38936665(+) A-I      intronic chr4:38923702(+) A-I      intronic chr4:38923662(+) A-I      intronic chr4:38923637(+) A-I      intronic chr4:38923627(+) A-I      intronic chr4:38923143(+) A-I      intronic chr4:38923079(+) A-I      intronic chr4:38922991(+) A-I      intronic chr4:38921749(+) A-I      intronic chr4:38921734(+) A-I      intronic chr4:38921730(+) A-I      intronic chr4:38921719(+) A-I      intronic chr4:38920695(+) A-I      intronic chr4:38918860(+) A-I      intronic chr4:38916152(+) A-I      intronic chr4:38916147(+) A-I      intronic chr4:38916072(+) A-I      intronic chr4:38916028(+) A-I      intronic chr4:38916027(+) A-I      intronic chr4:38916025(+) A-I      intronic chr4:38916024(+) A-I      intronic chr4:38915966(+) A-I      intronic chr4:38915610(+) A-I      intronic chr4:38915606(+) A-I      intronic chr4:38915601(+) A-I      intronic chr4:38915600(+) A-I      intronic chr4:38915245(+) A-I      intronic chr4:38915233(+) A-I      intronic chr4:38915232(+) A-I      intronic chr4:38915164(+) A-I      intronic chr4:38915075(+) A-I      intronic chr4:38915041(+) A-I      intronic chr4:38915039(+) A-I      intronic chr4:38914207(+) A-I      intronic chr4:38913679(+) A-I      intronic chr4:38913665(+) A-I      intronic chr4:38913563(+) A-I      intronic chr4:38911847(+) A-I      intronic chr4:38911820(+) A-I      intronic chr4:38911801(+) A-I      intronic chr4:38911698(+) A-I      intronic chr4:38911678(+) A-I      intronic chr4:38911676(+) A-I      intronic chr4:38906816(+) A-I      intronic chr4:38906808(+) A-I      intronic chr4:38890064(+) A-I      intronic chr4:38890063(+) A-I      intronic chr4:38890059(+) A-I      intronic chr4:38889910(+) A-I      intronic chr4:38889867(+) A-I      intronic chr4:38888469(+) A-I      intronic chr4:38888455(+) A-I      intronic chr4:38888012(+) A-I      intronic chr4:38887975(+) A-I      intronic chr4:38887030(+) A-I      intronic chr4:38886955(+) A-I      intronic chr4:38886839(+) A-I      intronic chr4:38886725(+) A-I      intronic chr4:38886713(+) A-I      intronic chr4:38895338(+) A-I      intronic chr4:38896193(+) A-I      intronic chr4:38896208(+) A-I      intronic chr4:38896637(+) A-I      intronic chr4:38896642(+) A-I      intronic chr4:38896673(+) A-I      intronic chr4:38896677(+) A-I      intronic chr4:38896678(+) A-I      intronic chr4:38898289(+) A-I      intronic chr4:38923028(+) A-I      intronic chr4:38944617(+) A-I      intronic chr4:38944611(+) A-I      intronic chr4:38944603(+) A-I      intronic chr4:38923020(+) A-I      intronic chr4:38923018(+) A-I      intronic chr4:38923013(+) A-I      intronic chr4:38923009(+) A-I      intronic chr4:38922965(+) A-I      intronic chr4:38921748(+) A-I      intronic chr4:38921709(+) A-I      intronic chr4:38921707(+) A-I      intronic chr4:38913756(+) A-I      intronic chr4:38913744(+) A-I      intronic chr4:38911739(+) A-I      intronic chr4:38921723(+) A-I      intronic chr4:38913725(+) A-I      intronic chr4:38913704(+) A-I      intronic chr4:38913587(+) A-I      intronic chr4:38913586(+) A-I      intronic chr4:38913583(+) A-I      intronic chr4:38913582(+) A-I      intronic chr4:38911812(+) A-I      intronic chr4:38911693(+) A-I      intronic chr4:38911677(+) A-I      intronic chr4:38911658(+) A-I      intronic chr4:38944749(+) A-I      intronic chr4:38944708(+) A-I      intronic chr4:38944699(+) A-I      intronic chr4:38941732(+) A-I      intronic chr4:38941692(+) A-I      intronic chr4:38941614(+) A-I      intronic chr4:38939621(+) A-I      intronic chr4:38939619(+) A-I      intronic chr4:38945890(+) A-I      3'UTR chr4:38945882(+) A-I      3'UTR chr4:38945855(+) A-I      3'UTR chr4:38945876(+) A-I      3'UTR chr4:38885793(+) A-I      intronic chr4:38923063(+) A-I      intronic chr4:38944667(+) A-I      intronic chr4:38937853(+) A-I      intronic chr4:38915132(+) A-I      intronic chr4:38923760(+) A-I      intronic chr4:38916066(+) A-I      intronic chr4:38911668(+) A-I      intronic chr4:38921597(+) A-I      intronic chr4:38886801(+) A-I      intronic chr4:38923117(+) A-I      intronic chr4:38915246(+) A-I      intronic chr4:38915494(+) A-I      intronic chr4:38923118(+) A-I      intronic chr4:38916089(+) A-I      intronic chr4:38915051(+) A-I      intronic chr4:38920544(+) A-I      intronic chr4:38945845(+) A-I      3'UTR chr4:38920318(+) A-I      intronic chr4:38915076(+) A-I      intronic chr4:38915044(+) A-I      intronic chr4:38915070(+) A-I      intronic chr4:38920653(+) A-I      intronic chr4:38944693(+) A-I      intronic chr4:38915263(+) A-I      intronic chr4:38913717(+) A-I      intronic chr4:38944626(+) A-I      intronic chr4:38923157(+) A-I      intronic chr4:38915195(+) A-I      intronic chr4:38891867(+) A-I      intronic chr4:38923135(+) A-I      intronic chr4:38913538(+) A-I      intronic chr4:38915144(+) A-I      intronic chr4:38911843(+) A-I      intronic chr4:38922940(+) A-I      intronic chr4:38915154(+) A-I      intronic chr4:38913647(+) A-I      intronic chr4:38913656(+) A-I      intronic chr4:38885830(+) A-I      intronic chr4:38911740(+) A-I      intronic chr4:38918654(+) A-I      intronic chr4:38889905(+) A-I      intronic chr4:38915485(+) A-I      intronic chr4:38881524(+) A-I      intronic chr4:38915181(+) A-I      intronic chr4:38921778(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	FAM114A1	chr4:38886801(+) A-G intron -    22484847 chr4:38914062(+) A-G intron -    22484847 chr4:38922948(+) A-G intron -    22484847 chr4:38922982(+) A-G intron -    22484847 chr4:38923063(+) A-G intron -    22484847 chr4:38923135(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	FAM114A1	chr4:38869415-38869416(+) m6A 5'UTR       24284625//24981863 chr4:38879736-38879737(+) m6A CDS//intron       24981863 chr4:38924509-38924510(+) m6A CDS//exon       27773535 chr4:38930944-38930945(+) m6A CDS//exon       24981863//27773535 chr4:38933110-38933111(+) m6A CDS//exon       24981863//27773535 chr4:38933152-38933153(+) m6A CDS//exon       24981863//27773535 chr4:38933186-38933187(+) m6A CDS//exon       24981863//27773535//22575960 chr4:38933198-38933199(+) m6A CDS//exon       24981863//27773535//22575960 chr4:38933218-38933219(+) m6A CDS//exon       24981863//27773535//22575960 chr4:38933224-38933225(+) m6A CDS//exon       24981863//27773535//22575960 chr4:38945151-38945152(+) m6A CDS//exon       24284625 chr4:38945187-38945188(+) m6A 3'UTR//exon       24284625 chr4:38945207-38945208(+) m6A 3'UTR//exon       24284625 chr4:38945272-38945273(+) m6A 3'UTR//exon       24284625//24209618//24981863//22608085 chr4:38945286-38945287(+) m6A 3'UTR//exon       24284625//24209618//24981863//22608085 chr4:38945309-38945310(+) m6A 3'UTR//exon       24284625//24209618//24981863 chr4:38945376-38945377(+) m6A 3'UTR//exon       24981863 chr4:38946808-38946809(+) m6A 3'UTR       24284625//24209618//24981863//27773535//22608085 chr4:38946875-38946876(+) m6A 3'UTR       24284625//24209618//24981863//27773535//22608085 chr4:38946939-38946940(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr4:38947044-38947045(+) m6A 3'UTR       24284625//24209618

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-548j-5p	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Fibroblasts|Mesenchymal stem cells     -
	FAM114A1	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)     - Exosome Blood     - Membrane HCC cell line (HepG2)     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-548j-5p
Interactor2: FAM114A1

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.