Basic Information:

  VIRBase ID:  

HHID00069373

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-548j-5p:  MIMAT0005875          PALB2:  NM_024675     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-548j-5p	PALB2
miRBase Accession/Entrez ID	MIMAT0005875	79728
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	FANCN//PNCA3

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-548j-5p	rs1210209539 chr22:26555275    C/T rs545900525 chr22:26555280    G/C rs565141718 chr22:26555283    C/A rs565141718 chr22:26555283    C/G rs565141718 chr22:26555283    C/T rs751780445 chr22:26555284    G/A rs753744163 chr22:26555282    C/A rs757533254 chr22:26555285    C/A rs367750295 chr22:26555290    A/G rs976434292 chr22:26555292    T/C

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	PALB2	chr16:23616851(-) A-I      intronic chr16:23616898(-) A-I      intronic chr16:23624256(-) A-I      intronic chr16:23624252(-) A-I      intronic chr16:23624247(-) A-I      intronic chr16:23624267(-) A-I      intronic chr16:23624241(-) A-I      intronic chr16:23651389(-) A-I      intronic chr16:23637194(-) A-I      intronic chr16:23621278(-) A-I      intronic chr16:23651377(-) A-I      intronic chr16:23651058(-) A-I      intronic chr16:23640228(-) A-I      intronic chr16:23642658(-) A-I      intronic chr16:23643236(-) A-I      intronic chr16:23643289(-) A-I      intronic chr16:23643703(-) A-I      intronic chr16:23644291(-) A-I      intronic chr16:23644298(-) A-I      intronic chr16:23644303(-) A-I      intronic chr16:23645185(-) A-I      intronic chr16:23645243(-) A-I      intronic chr16:23645752(-) A-I      intronic chr16:23638745(-) A-I      intronic chr16:23638696(-) A-I      intronic chr16:23638214(-) A-I      intronic chr16:23638016(-) A-I      intronic chr16:23637207(-) A-I      intronic chr16:23650619(-) A-I      intronic chr16:23650685(-) A-I      intronic chr16:23650691(-) A-I      intronic chr16:23650896(-) A-I      intronic chr16:23650898(-) A-I      intronic chr16:23650924(-) A-I      intronic chr16:23650975(-) A-I      intronic chr16:23622211(-) A-I      intronic chr16:23616747(-) A-I      intronic chr16:23621870(-) A-I      intronic chr16:23621833(-) A-I      intronic chr16:23621722(-) A-I      intronic chr16:23621715(-) A-I      intronic chr16:23640227(-) A-I      intronic chr16:23640182(-) A-I      intronic chr16:23640143(-) A-I      intronic chr16:23640130(-) A-I      intronic chr16:23640125(-) A-I      intronic chr16:23621695(-) A-I      intronic chr16:23640124(-) A-I      intronic chr16:23640066(-) A-I      intronic chr16:23639420(-) A-I      intronic chr16:23639375(-) A-I      intronic chr16:23639328(-) A-I      intronic chr16:23639301(-) A-I      intronic chr16:23639300(-) A-I      intronic chr16:23639288(-) A-I      intronic chr16:23638751(-) A-I      intronic chr16:23621852(-) A-I      intronic chr16:23620646(-) A-I      intronic chr16:23620699(-) A-I      intronic chr16:23631261(-) A-I      intronic chr16:23621198(-) A-I      intronic chr16:23637035(-) A-I      intronic chr16:23636933(-) A-I      intronic chr16:23636924(-) A-I      intronic chr16:23636895(-) A-I      intronic chr16:23636894(-) A-I      intronic chr16:23635973(-) A-I      intronic chr16:23635972(-) A-I      intronic chr16:23632448(-) A-I      intronic chr16:23631333(-) A-I      intronic chr16:23631327(-) A-I      intronic chr16:23631301(-) A-I      intronic chr16:23631239(-) A-I      intronic chr16:23631225(-) A-I      intronic chr16:23631216(-) A-I      intronic chr16:23631193(-) A-I      intronic chr16:23629940(-) A-I      intronic chr16:23629615(-) A-I      intronic chr16:23629508(-) A-I      intronic chr16:23629399(-) A-I      intronic chr16:23629385(-) A-I      intronic chr16:23629363(-) A-I      intronic chr16:23627097(-) A-I      intronic chr16:23627082(-) A-I      intronic chr16:23627013(-) A-I      intronic chr16:23626825(-) A-I      intronic chr16:23624882(-) A-I      intronic chr16:23624878(-) A-I      intronic chr16:23624856(-) A-I      intronic chr16:23624301(-) A-I      intronic chr16:23624146(-) A-I      intronic chr16:23623986(-) A-I      intronic chr16:23623684(-) A-I      intronic chr16:23623664(-) A-I      intronic chr16:23623574(-) A-I      intronic chr16:23622895(-) A-I      intronic chr16:23622664(-) A-I      intronic chr16:23622638(-) A-I      intronic chr16:23622613(-) A-I      intronic chr16:23622605(-) A-I      intronic chr16:23618849(-) A-I      intronic chr16:23618829(-) A-I      intronic chr16:23618682(-) A-I      intronic chr16:23617998(-) A-I      intronic chr16:23617669(-) A-I      intronic chr16:23617640(-) A-I      intronic chr16:23616924(-) A-I      intronic chr16:23616874(-) A-I      intronic chr16:23616868(-) A-I      intronic chr16:23616867(-) A-I      intronic chr16:23616832(-) A-I      intronic chr16:23616765(-) A-I      intronic chr16:23651703(-) A-I      intronic chr16:23621923(-) A-I      intronic chr16:23624865(-) A-I      intronic chr16:23621231(-) A-I      intronic chr16:23650757(-) A-I      intronic chr16:23622115(-) A-I      intronic chr16:23650635(-) A-I      intronic chr16:23631376(-) A-I      intronic chr16:23624743(-) A-I      intronic chr16:23616319(-) A-I      intronic chr16:23651268(-) A-I      intronic chr16:23622561(-) A-I      intronic chr16:23626704(-) A-I      intronic chr16:23620664(-) A-I      intronic chr16:23629465(-) A-I      intronic chr16:23645127(-) A-I      intronic chr16:23651122(-) A-I      intronic chr16:23624166(-) A-I      intronic chr16:23651303(-) A-I      intronic chr16:23616909(-) A-I      intronic chr16:23616908(-) A-I      intronic chr16:23617674(-) A-I      intronic chr16:23645233(-) A-I      intronic chr16:23642690(-) A-I      intronic chr16:23627020(-) A-I      intronic chr16:23622194(-) A-I      intronic chr16:23626898(-) A-I      intronic chr16:23622114(-) A-I      intronic chr16:23629557(-) A-I      intronic chr16:23650978(-) A-I      intronic chr16:23650984(-) A-I      intronic chr16:23645889(-) A-I      intronic chr16:23651444(-) A-I      intronic chr16:23624853(-) A-I      intronic chr16:23650682(-) A-I      intronic chr16:23616030(-) A-I      intronic chr16:23638081(-) A-I      intronic chr16:23650897(-) A-I      intronic chr16:23651059(-) A-I      intronic chr16:23621255(-) A-I      intronic chr16:23626378(-) A-I      intronic chr16:23644223(-) A-I      intronic chr16:23622174(-) A-I      intronic chr16:23644333(-) A-I      intronic chr16:23622113(-) A-I      intronic chr16:23623226(-) A-I      intronic chr16:23651742(-) A-I      intronic chr16:23639558(-) A-I      intronic chr16:23620663(-) A-I      intronic chr16:23622261(-) A-I      intronic chr16:23645825(-) A-I      intronic chr16:23640058(-) A-I      intronic chr16:23640095(-) A-I      intronic chr16:23639548(-) A-I      intronic chr16:23632246(-) A-I      intronic chr16:23651725(-) A-I      intronic chr16:23626448(-) A-I      intronic chr16:23639445(-) A-I      intronic chr16:23645890(-) A-I      intronic chr16:23651351(-) A-I      intronic chr16:23626430(-) A-I      intronic chr16:23640060(-) A-I      intronic chr16:23621246(-) A-I      intronic chr16:23624889(-) A-I      intronic chr16:23620740(-) A-I      intronic chr16:23651214(-) A-I      intronic chr16:23622534(-) A-I      intronic chr16:23620732(-) A-I      intronic chr16:23622972(-) A-I      intronic chr16:23621217(-) A-I      intronic chr16:23622191(-) A-I      intronic chr16:23651312(-) A-I      intronic chr16:23639376(-) A-I      intronic chr16:23622570(-) A-I      intronic chr16:23615922(-) A-I      intronic chr16:23650992(-) A-I      intronic chr16:23621178(-) A-I      intronic chr16:23639546(-) A-I      intronic chr16:23651421(-) A-I      intronic chr16:23638107(-) A-I      intronic chr16:23620686(-) A-I      intronic chr16:23621907(-) A-I      intronic chr16:23615987(-) A-I      intronic chr16:23640052(-) A-I      intronic chr16:23617619(-) A-I      intronic chr16:23624843(-) A-I      intronic chr16:23628970(-) A-I      intronic chr16:23632512(-) A-I      intronic chr16:23621702(-) A-I      intronic chr16:23651454(-) A-I      intronic chr16:23645726(-) A-I      intronic chr16:23628947(-) A-I      intronic chr16:23615925(-) A-I      intronic chr16:23651803(-) A-I      intronic chr16:23621226(-) A-I      intronic chr16:23643682(-) A-I      intronic chr16:23617627(-) A-I      intronic chr16:23622249(-) A-I      intronic chr16:23621272(-) A-I      intronic chr16:23624238(-) A-I      intronic chr16:23638116(-) A-I      intronic chr16:23639379(-) A-I      intronic chr16:23650662(-) A-I      intronic chr16:23650969(-) A-I      intronic chr16:23621807(-) A-I      intronic chr16:23622567(-) A-I      intronic chr16:23650754(-) A-I      intronic chr16:23621768(-) A-I      intronic chr16:23622239(-) A-I      intronic chr16:23645173(-) A-I      intronic chr16:23627028(-) A-I      intronic chr16:23624913(-) A-I      intronic chr16:23650993(-) A-I      intronic chr16:23620596(-) A-I      intronic chr16:23621250(-) A-I      intronic chr16:23651484(-) A-I      intronic chr16:23622832(-) A-I      intronic chr16:23638113(-) A-I      intronic chr16:23622173(-) A-I      intronic chr16:23645773(-) A-I      intronic chr16:23622955(-) A-I      intronic chr16:23628944(-) A-I      intronic chr16:23630785(-) A-I      intronic chr16:23622896(-) A-I      intronic chr16:23626434(-) A-I      intronic chr16:23622274(-) A-I      intronic chr16:23632247(-) A-I      intronic chr16:23636532(-) A-I      intronic chr16:23632495(-) A-I      intronic chr16:23644332(-) A-I      intronic chr16:23621758(-) A-I      intronic chr16:23623700(-) A-I      intronic chr16:23640263(-) A-I      intronic chr16:23640262(-) A-I      intronic chr16:23617599(-) A-I      intronic chr16:23623921(-) A-I      intronic chr16:23651238(-) A-I      intronic chr16:23650637(-) A-I      intronic chr16:23645148(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	PALB2	chr16:23621768(-) A-I intron -    22327324 chr16:23621178(-) A-G intron -    22484847 chr16:23621768(-) A-G intron -    22484847 chr16:23624166(-) A-G intron -    22484847 chr16:23624238(-) A-G intron -    22484847 chr16:23626676(-) T-C intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	PALB2	chr16:23614837-23614838(-) m6A 3'UTR//CDS       24981863 chr16:23634298-23634299(-) Am CDS       - chr16:23640558-23640559(-) m6A 3'UTR//CDS       24284625 chr16:23640589-23640590(-) m6A 3'UTR//CDS       24284625//27773535//22608085 chr16:23640963-23640964(-) m6A CDS//intron       24284625//27773535//22608085 chr16:23640975-23640976(-) m6A CDS//intron       24284625//24209618//24981863//27773535//22608085 chr16:23640997-23640998(-) m6A CDS//intron       24284625//24209618//24981863//27773535//22608085 chr16:23641049-23641050(-) m6A CDS//intron       24284625//24209618//24981863//27773535//22575960//22608085 chr16:23641086-23641087(-) m6A CDS//intron       24284625//24209618//24981863//27773535//22575960//22608085 chr16:23641122-23641123(-) m6A CDS//intron       24284625//24209618//24981863//27773535//22575960//22608085 chr16:23641152-23641153(-) m6A CDS//intron       24284625//24209618//24981863//27773535//22575960//22608085 chr16:23641180-23641181(-) m6A CDS//intron       24284625//24209618//24981863//27773535//22575960//22608085 chr16:23641214-23641215(-) m6A CDS//intron       24284625//24209618//24981863//27773535//22575960//22608085 chr16:23641309-23641310(-) m6A CDS//intron       24284625//24209618//24981863//27773535//22575960//22608085 chr16:23641411-23641412(-) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085 chr16:23641453-23641454(-) m6A CDS//intron       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr16:23641465-23641466(-) m6A CDS//intron       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr16:23641500-23641501(-) m6A CDS//intron       24284625//24209618//25456834//24981863//27773535//27371828//22608085 chr16:23641536-23641537(-) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22608085 chr16:23641575-23641576(-) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22608085 chr16:23641614-23641615(-) m6A CDS//intron       24284625//25456834//24981863//27773535//22608085 chr16:23641621-23641622(-) m6A CDS//intron       24284625//25456834//24981863//27773535//22608085 chr16:23641642-23641643(-) m6A CDS//intron       24284625//25456834//24981863//27773535//22608085 chr16:23646282-23646283(-) m6A CDS//intron       24284625//24981863//27773535//22608085 chr16:23646426-23646427(-) m6A CDS//intron       24284625//24209618//24981863//27773535//22608085 chr16:23646437-23646438(-) m6A CDS//intron       24284625//24209618//24981863//27773535//22608085 chr16:23646453-23646454(-) m6A CDS//intron       24284625//24981863//27773535//22608085 chr16:23646494-23646495(-) m6A CDS//intron       24284625//24981863//27773535//22608085 chr16:23646511-23646512(-) m6A CDS//intron       24284625//24981863//27773535//22608085 chr16:23646632-23646633(-) m6A CDS//intron       24981863//27773535//22608085 chr16:23646687-23646688(-) m6A CDS//intron       24981863//27773535//22608085 chr16:23646815-23646816(-) m6A CDS//intron       24284625//24981863//27773535//22608085 chr16:23646825-23646826(-) m6A CDS//intron       24284625//24981863//27773535//22608085 chr16:23646835-23646836(-) m6A CDS//intron       24284625//24981863//27773535//22608085 chr16:23646841-23646842(-) m6A CDS//intron       24284625//24981863//27773535//22608085 chr16:23646873-23646874(-) m6A CDS//intron       24284625//24981863//27773535//22608085 chr16:23647027-23647028(-) m6A 5'UTR//CDS//intron       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr16:23647050-23647051(-) m6A 5'UTR//CDS//intron       24284625//24209618//24981863//27773535//22575960//22608085 chr16:23647077-23647078(-) m6A 5'UTR//CDS//intron       24284625//24209618//24981863//27773535//22575960//22608085 chr16:23647112-23647113(-) m6A 5'UTR//CDS//intron       24284625//24209618//24981863//27773535//22575960//22608085 chr16:23647149-23647150(-) m6A 5'UTR//CDS//intron       24284625//24209618//24981863//27773535//22575960//22608085 chr16:23647210-23647211(-) m6A 5'UTR//CDS//intron       24284625//24981863//27773535//22575960//22608085 chr16:23647233-23647234(-) m6A 5'UTR//CDS//intron       24284625//24981863//27773535//22575960//22608085 chr16:23647251-23647252(-) m6A 5'UTR//CDS//intron       24284625//24981863//27773535//22575960//22608085 chr16:23647277-23647278(-) m6A 5'UTR//CDS//intron       24284625//25456834//24981863//27773535//22575960//22608085 chr16:23647332-23647333(-) m6A 5'UTR//CDS//intron       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr16:23647341-23647342(-) m6A 5'UTR//CDS//intron       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085 chr16:23647384-23647385(-) m6A 5'UTR//CDS//exon//intron       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085 chr16:23647406-23647407(-) m6A 5'UTR//CDS//exon//intron       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085 chr16:23647488-23647489(-) m6A 5'UTR//CDS//exon//intron       24284625//24209618//25456834//24981863//27773535//27371828//22608085 chr16:23647505-23647506(-) m6A 5'UTR//CDS//exon//intron       24284625//25456834//24981863//27773535//22608085 chr16:23647580-23647581(-) m6A 5'UTR//CDS//exon//intron       24284625//24981863//27773535//22608085 chr16:23647592-23647593(-) m6A 5'UTR//CDS//exon//intron       24284625//24981863//27773535//22608085 chr16:23647610-23647611(-) m6A 5'UTR//CDS//exon//intron       24284625//24981863//27773535//22608085 chr16:23649177-23649178(-) m6A 5'UTR//CDS//exon       27773535 chr16:23649219-23649220(-) m6A 5'UTR//CDS//exon       27773535 chr16:23649230-23649231(-) m6A 5'UTR//CDS//exon       27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-548j-5p	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Fibroblasts|Mesenchymal stem cells     -
	PALB2	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol K562 cells     - Exosome Blood     - Insoluble cytoplasm HCC cell line (HepG2)     - Membrane HCC cell line (HepG2)     - Nucleus HCC cell line (HepG2)|K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-548j-5p
Interactor2: PALB2

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	CDS
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.