Detail Information

Basic Information:


  VIRBase ID:  

HHID00069264

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-548j-5p:           RYBP:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-548j-5p RYBP
miRBase
Accession/Entrez ID		 MIMAT0005875 23429
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - AAP1//APAP-1//DEDAF//YEAF1

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-548j-5p
rs1210209539 chr22:26555275    C/T
rs545900525 chr22:26555280    G/C
rs565141718 chr22:26555283    C/A
rs565141718 chr22:26555283    C/G
rs565141718 chr22:26555283    C/T
rs751780445 chr22:26555284    G/A
rs753744163 chr22:26555282    C/A
rs757533254 chr22:26555285    C/A
rs367750295 chr22:26555290    A/G
rs976434292 chr22:26555292    T/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR RYBP
chr3:72485152(-) A-I      intronic
chr3:72485339(-) A-I      intronic
chr3:72485384(-) A-I      intronic
chr3:72492431(-) A-I      intronic
chr3:72492421(-) A-I      intronic
chr3:72442260(-) A-I      intronic
chr3:72442288(-) A-I      intronic
chr3:72442290(-) A-I      intronic
chr3:72442327(-) A-I      intronic
chr3:72442435(-) A-I      intronic
chr3:72442438(-) A-I      intronic
chr3:72442446(-) A-I      intronic
chr3:72459179(-) A-I      intronic
chr3:72459083(-) A-I      intronic
chr3:72465838(-) A-I      intronic
chr3:72465843(-) A-I      intronic
chr3:72465846(-) A-I      intronic
chr3:72465901(-) A-I      intronic
chr3:72442421(-) A-I      intronic
chr3:72442447(-) A-I      intronic
chr3:72489458(-) A-I      intronic
chr3:72485250(-) A-I      intronic
chr3:72474470(-) A-I      intronic
chr3:72465317(-) A-I      intronic
chr3:72465852(-) A-I      intronic
chr3:72446211(-) A-I      intronic
chr3:72442451(-) A-I      intronic
chr3:72492483(-) A-I      intronic
chr3:72442282(-) A-I      intronic
chr3:72484439(-) A-I      intronic
chr3:72465837(-) A-I      intronic
chr3:72429814(-) A-I      intronic
chr3:72442393(-) A-I      intronic
chr3:72474486(-) A-I      intronic
chr3:72429746(-) A-I      intronic
chr3:72442420(-) A-I      intronic
chr3:72465861(-) A-I      intronic
chr3:72459112(-) A-I      intronic
chr3:72465291(-) A-I      intronic
chr3:72465223(-) A-I      intronic
chr3:72443845(-) A-I      intronic
chr3:72429747(-) A-I      intronic
chr3:72442450(-) A-I      intronic
chr3:72446213(-) A-I      intronic
chr3:72485308(-) A-I      intronic
chr3:72442504(-) A-I      intronic
chr3:72478884(-) A-I      intronic
chr3:72465808(-) A-I      intronic
chr3:72465879(-) A-I      intronic
chr3:72442315(-) A-I      intronic
chr3:72469337(-) A-I      intronic
chr3:72465242(-) A-I      intronic
chr3:72489600(-) A-I      intronic
chr3:72476761(-) A-I      intronic
chr3:72442311(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED RYBP
chr3:72442450(-) A-I intron -    22327324
chr3:72489089(-) A-G intron -    22484847
chr3:72442282(-) A-G intron -    22484847
chr3:72442311(-) A-G intron -    22484847
chr3:72442312(-) A-G intron -    22484847
chr3:72442315(-) A-G intron -    22484847
chr3:72442316(-) A-G intron -    22484847
chr3:72442393(-) A-G intron -    22484847
chr3:72442421(-) A-G intron -    22484847
chr3:72442447(-) A-G intron -    22484847
chr3:72442450(-) A-G intron -    22484847
chr3:72442451(-) A-G intron -    22484847
chr3:72442481(-) A-G intron -    22484847
chr3:72446211(-) A-G intron -    22484847
chr3:72446213(-) A-G intron -    22484847
chr3:72459112(-) A-G intron -    22484847
chr3:72459113(-) A-G intron -    22484847
chr3:72459210(-) A-C intron -    22484847
chr3:72465317(-) A-G intron -    22484847
chr3:72465837(-) A-G intron -    22484847
chr3:72465852(-) A-G intron -    22484847
chr3:72465861(-) A-G intron -    22484847
chr3:72474444(-) T-C intron -    22484847
chr3:72476627(-) G-A intron -    22484847
chr3:72476761(-) A-G intron -    22484847
chr3:72484361(-) A-G intron -    22484847
chr3:72484439(-) A-G intron -    22484847
chr3:72484549(-) A-G intron -    22484847
chr3:72485249(-) A-G intron -    22484847
chr3:72485250(-) A-G intron -    22484847
chr3:72485307(-) A-G intron -    22484847
chr3:72485308(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase RYBP
chr3:72423411-72423412(-) m6A 3'UTR       27773535
chr3:72423429-72423430(-) m6A 3'UTR       27773535
chr3:72424984-72424985(-) m6A 3'UTR       -
chr3:72425016-72425017(-) m6A 3'UTR       -
chr3:72425030-72425031(-) m1A 3'UTR       26863410
chr3:72426790-72426791(-) m6A 3'UTR       24981863//26404942
chr3:72426813-72426814(-) m6A 3'UTR       24981863//26404942//22608085
chr3:72426872-72426873(-) m6A 3'UTR       24981863//22608085
chr3:72427438-72427439(-) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22608085
chr3:72427485-72427486(-) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085
chr3:72427512-72427513(-) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085
chr3:72427602-72427603(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr3:72427632-72427633(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr3:72427640-72427641(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr3:72427693-72427694(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr3:72427707-72427708(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22608085
chr3:72427767-72427768(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22608085
chr3:72428206-72428207(-) m6A CDS       24284625//24209618//24981863//28052920//27773535//27371828//22608085
chr3:72428215-72428216(-) m6A CDS       24284625//24209618//24981863//28052920//27773535//27371828//22608085
chr3:72428247-72428248(-) m6A CDS       24284625//24209618//24981863//27773535//27371828//22608085
chr3:72428405-72428406(-) m6A CDS       24284625//24981863//27773535//27371828//22608085
chr3:72428452-72428453(-) m6A CDS       24981863//27773535//27371828//22608085
chr3:72428463-72428464(-) m6A CDS       24981863//27773535//27371828//22608085
chr3:72428473-72428474(-) m6A CDS       24981863//27773535//27371828//22608085
chr3:72428574-72428575(-) m6A CDS       27773535//27371828
chr3:72495703-72495704(-) m6A CDS       27773535

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-548j-5p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
RYBP
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol HCC cell line (HepG2)|K562 cells     -
Exosome Blood     -
Membrane K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)|K562 cells     -
Ribosome HEK-293 cells     22199352

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-548j-5p
Interactor2: RYBP

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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