Detail Information

Basic Information:


  VIRBase ID:  

HHID00069262

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-548j-5p:           PLCL2:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-548j-5p PLCL2
miRBase
Accession/Entrez ID		 MIMAT0005875 23228
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - PLCE2

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-548j-5p
rs1210209539 chr22:26555275    C/T
rs545900525 chr22:26555280    G/C
rs565141718 chr22:26555283    C/A
rs565141718 chr22:26555283    C/G
rs565141718 chr22:26555283    C/T
rs751780445 chr22:26555284    G/A
rs753744163 chr22:26555282    C/A
rs757533254 chr22:26555285    C/A
rs367750295 chr22:26555290    A/G
rs976434292 chr22:26555292    T/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR PLCL2
chr3:17028037(+) A-I      intronic
chr3:17028033(+) A-I      intronic
chr3:17028020(+) A-I      intronic
chr3:17010311(+) A-I      intronic
chr3:17010323(+) A-I      intronic
chr3:17027994(+) A-I      intronic
chr3:17026376(+) A-I      intronic
chr3:17026351(+) A-I      intronic
chr3:17026267(+) A-I      intronic
chr3:17026247(+) A-I      intronic
chr3:17026246(+) A-I      intronic
chr3:17025055(+) A-I      intronic
chr3:17010361(+) A-I      intronic
chr3:17048719(+) A-I      intronic
chr3:17010358(+) A-I      intronic
chr3:17048717(+) A-I      intronic
chr3:17071672(+) A-I      intronic
chr3:17113419(+) A-I      intronic
chr3:17114005(+) A-I      intronic
chr3:17113996(+) A-I      intronic
chr3:17010328(+) A-I      intronic
chr3:17113571(+) A-I      intronic
chr3:17028142(+) A-I      intronic
chr3:17113383(+) A-I      intronic
chr3:17113382(+) A-I      intronic
chr3:17113897(+) A-I      intronic
chr3:16956315(+) A-I      intronic
chr3:17113528(+) A-I      intronic
chr3:16968328(+) A-I      intronic
chr3:17027925(+) A-I      intronic
chr3:16968305(+) A-I      intronic
chr3:16944172(+) A-I      intronic
chr3:17113946(+) A-I      intronic
chr3:16944164(+) A-I      intronic
chr3:17113941(+) A-I      intronic
chr3:17113899(+) A-I      intronic
chr3:17028157(+) A-I      intronic
chr3:17113493(+) A-I      intronic
chr3:17027955(+) A-I      intronic
chr3:17113533(+) A-I      intronic
chr3:17028023(+) A-I      intronic
chr3:17113905(+) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED PLCL2
chr3:16993604(+) A-G intron -    22484847
chr3:16995548(+) A-G intron -    22484847
chr3:16944173(+) G-A intron -    22484847
chr3:16956315(+) A-G intron -    22484847
chr3:16968305(+) A-G intron -    22484847
chr3:16968328(+) A-G intron -    22484847
chr3:16975299(+) T-C intron -    22484847
chr3:16975459(+) G-T intron -    22484847
chr3:16975474(+) G-A intron -    22484847
chr3:16988614(+) A-T intron -    22484847
chr3:16988619(+) A-T intron -    22484847
chr3:17026147(+) A-G intron -    22484847
chr3:17026170(+) A-G intron -    22484847
chr3:17027925(+) A-G intron -    22484847
chr3:17027955(+) A-G intron -    22484847
chr3:17028023(+) A-G intron -    22484847
chr3:17069974(+) C-T intron -    22484847
chr3:17113350(+) A-G intron -    22484847
chr3:17113493(+) A-G intron -    22484847
chr3:17113528(+) A-G intron -    22484847
chr3:17113533(+) A-G intron -    22484847
chr3:17113899(+) A-G intron -    22484847
chr3:17113905(+) A-G intron -    22484847
chr3:17113941(+) A-G intron -    22484847
chr3:17113946(+) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase PLCL2
chr3:16926710-16926711(+) m6A CDS//intron       24981863
chr3:16926762-16926763(+) m6A CDS//intron       24981863//22575960
chr3:16974604-16974605(+) m6A 5'UTR//intron       24981863
chr3:17051176-17051177(+) m6A 5'UTR//CDS//exon       24981863//22608085
chr3:17051198-17051199(+) m6A 5'UTR//CDS//exon       24209618//24981863//22608085
chr3:17051281-17051282(+) m6A CDS//exon       24209618//24981863//22608085
chr3:17051423-17051424(+) m6A CDS//exon       24284625//24981863//22608085
chr3:17051433-17051434(+) m6A CDS//exon       24284625//24981863//22608085
chr3:17051439-17051440(+) m6A CDS//exon       24284625//24981863//22608085
chr3:17051556-17051557(+) m6A CDS//exon       24284625//24981863//26404942//22575960//22608085
chr3:17051572-17051573(+) m6A CDS//exon       24284625//24981863//26404942//22575960//22608085
chr3:17051599-17051600(+) m6A CDS//intron       24284625//24981863//26404942//22575960//22608085
chr3:17051642-17051643(+) m6A CDS//intron       24284625//24981863//22575960//22608085
chr3:17051692-17051693(+) m6A CDS//intron       24284625//24981863//22575960//22608085
chr3:17051730-17051731(+) m6A CDS//intron       24284625//24981863//22575960//22608085
chr3:17051796-17051797(+) m6A CDS//intron       24981863//22608085
chr3:17051860-17051861(+) m6A CDS//intron       24981863//22608085
chr3:17052004-17052005(+) m6A CDS//intron       22608085
chr3:17052097-17052098(+) m6A CDS//intron       24981863//22608085
chr3:17052150-17052151(+) m6A CDS//intron       24981863//22608085
chr3:17052273-17052274(+) m6A CDS//intron       24981863//22608085
chr3:17052280-17052281(+) m6A CDS//intron       24981863//22608085
chr3:17052399-17052400(+) m6A CDS//exon       24981863
chr3:17052415-17052416(+) m6A CDS//exon       24981863
chr3:17052636-17052637(+) m6A CDS       24981863//22608085
chr3:17052688-17052689(+) m6A CDS       24981863//22608085
chr3:17052697-17052698(+) m6A CDS       24981863//22608085
chr3:17052825-17052826(+) m6A CDS       24981863//26404942//22575960//22608085
chr3:17052945-17052946(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr3:17052953-17052954(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr3:17052961-17052962(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr3:17052972-17052973(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr3:17053005-17053006(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr3:17053074-17053075(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr3:17053131-17053132(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr3:17053225-17053226(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr3:17053232-17053233(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr3:17053238-17053239(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr3:17053306-17053307(+) m6A CDS       24284625//25456834//24981863//22575960//22608085
chr3:17131226-17131227(+) m6A CDS       25456834//24981863//22608085
chr3:17131260-17131261(+) m6A CDS       24284625//25456834//24981863//22608085
chr3:17131270-17131271(+) m6A CDS       24284625//25456834//24981863//22608085
chr3:17131277-17131278(+) m6A CDS       24284625//25456834//24981863//22608085
chr3:17131307-17131308(+) m6A CDS       24284625//25456834//24981863//22608085
chr3:17131316-17131317(+) m6A CDS       24284625//25456834//24981863//22575960//22608085
chr3:17131392-17131393(+) m6A CDS       24284625//25456834//24981863//26404942//22575960//22608085
chr3:17131408-17131409(+) m6A 3'UTR       24284625//25456834//24981863//26404942//22575960//22608085
chr3:17131419-17131420(+) m6A 3'UTR       24284625//25456834//24981863//26404942//22575960//22608085
chr3:17131445-17131446(+) m6A 3'UTR       24284625//24981863//26404942//22575960//22608085
chr3:17131465-17131466(+) m6A 3'UTR       24284625//24981863//22575960//22608085
chr3:17131546-17131547(+) m6A 3'UTR       24284625//24981863//22575960//22608085
chr3:17131588-17131589(+) m6A 3'UTR       24284625//24981863//22608085
chr3:17131644-17131645(+) m6A 3'UTR       24981863//22608085
chr3:17131701-17131702(+) m6A 3'UTR       24981863//22608085
chr3:17131719-17131720(+) m6A 3'UTR       24981863//22608085
chr3:17131778-17131779(+) m6A 3'UTR       22608085
chr3:17131944-17131945(+) m6A 3'UTR       25456834//24981863//22608085
chr3:17132020-17132021(+) m6A 3'UTR       25456834//24981863//22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-548j-5p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
PLCL2
Exosome Blood     -
Nucleus HeLa-S3 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-548j-5p
Interactor2: PLCL2

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region CDS
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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