Basic Information:

  VIRBase ID:  

HHID00069238

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-548j-5p:  MIMAT0005875          MARCHF6:  NM_001270661     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-548j-5p	MARCHF6
miRBase Accession/Entrez ID	MIMAT0005875	10299
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	DOA10//FAME3//MARCH-VI//MARCH6//RNF176//TEB4

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-548j-5p	rs1210209539 chr22:26555275    C/T rs545900525 chr22:26555280    G/C rs565141718 chr22:26555283    C/A rs565141718 chr22:26555283    C/G rs565141718 chr22:26555283    C/T rs751780445 chr22:26555284    G/A rs753744163 chr22:26555282    C/A rs757533254 chr22:26555285    C/A rs367750295 chr22:26555290    A/G rs976434292 chr22:26555292    T/C

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	MARCHF6	chr5:10359892(+) A-I      intronic chr5:10360022(+) A-I      intronic chr5:10360097(+) A-I      intronic chr5:10360105(+) A-I      intronic chr5:10368865(+) A-I      intronic chr5:10368490(+) A-I      intronic chr5:10368956(+) A-I      intronic chr5:10368961(+) A-I      intronic chr5:10370290(+) A-I      intronic chr5:10370292(+) A-I      intronic chr5:10370298(+) A-I      intronic chr5:10380743(+) A-I      intronic chr5:10380918(+) A-I      intronic chr5:10360030(+) A-I      intronic chr5:10380924(+) A-I      intronic chr5:10392679(+) A-I      intronic chr5:10392690(+) A-I      intronic chr5:10392719(+) A-I      intronic chr5:10392755(+) A-I      intronic chr5:10392772(+) A-I      intronic chr5:10407816(+) A-I      intronic chr5:10407907(+) A-I      intronic chr5:10407921(+) A-I      intronic chr5:10407989(+) A-I      intronic chr5:10428593(+) A-I      intronic chr5:10429637(+) A-I      intronic chr5:10429742(+) A-I      intronic chr5:10429748(+) A-I      intronic chr5:10393317(+) A-I      intronic chr5:10392798(+) A-I      intronic chr5:10359888(+) A-I      intronic chr5:10360366(+) A-I      intronic chr5:10360020(+) A-I      intronic chr5:10380851(+) A-I      intronic chr5:10392746(+) A-I      intronic chr5:10429526(+) A-I      intronic chr5:10392680(+) A-I      intronic chr5:10368785(+) A-I      intronic chr5:10409172(+) A-I      intronic chr5:10408919(+) A-I      intronic chr5:10392246(+) A-I      intronic chr5:10368481(+) A-I      intronic chr5:10380874(+) A-I      intronic chr5:10392781(+) A-I      intronic chr5:10380782(+) A-I      intronic chr5:10368544(+) A-I      intronic chr5:10368905(+) A-I      intronic chr5:10368947(+) A-I      intronic chr5:10368483(+) A-I      intronic chr5:10382498(+) A-I      intronic chr5:10368894(+) A-I      intronic chr5:10380908(+) A-I      intronic chr5:10407810(+) A-I      intronic chr5:10393231(+) A-I      intronic chr5:10359971(+) A-I      intronic chr5:10380760(+) A-I      intronic chr5:10368791(+) A-I      intronic chr5:10382756(+) A-I      intronic chr5:10429732(+) A-I      intronic chr5:10380919(+) A-I      intronic chr5:10380799(+) A-I      intronic chr5:10407811(+) A-I      intronic chr5:10372083(+) A-I      intronic chr5:10356691(+) A-I      intronic chr5:10360428(+) A-I      intronic chr5:10408763(+) A-I      intronic chr5:10382819(+) A-I      intronic chr5:10368656(+) A-I      intronic chr5:10393307(+) A-I      intronic chr5:10368467(+) A-I      intronic chr5:10407905(+) A-I      intronic chr5:10360331(+) A-I      intronic chr5:10380852(+) A-I      intronic chr5:10368831(+) A-I      intronic chr5:10368792(+) A-I      intronic chr5:10379841(+) A-I      intronic chr5:10368607(+) A-I      intronic chr5:10407948(+) A-I      intronic chr5:10392252(+) A-I      intronic chr5:10392641(+) A-I      intronic chr5:10392713(+) A-I      intronic chr5:10387900(+) A-I      intronic chr5:10408880(+) A-I      intronic chr5:10427966(+) A-I      intronic chr5:10382401(+) A-I      intronic chr5:10380788(+) A-I      intronic chr5:10368669(+) A-I      intronic chr5:10380984(+) A-I      intronic chr5:10407882(+) A-I      intronic

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-548j-5p	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Fibroblasts|Mesenchymal stem cells     -
	MARCHF6	Chromatin K562 cells     - Cytosol HCC cell line (HepG2)|K562 cells     - Exosome Blood     - Insoluble cytoplasm HCC cell line (HepG2)     - Membrane HCC cell line (HepG2)|K562 cells     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-548j-5p
Interactor2: MARCHF6

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	CDS
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.