Basic Information:

  VIRBase ID:  

HHID00069076

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-548e-3p:  MIMAT0005874          RNF11:  NM_014372     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-548e-3p	RNF11
miRBase Accession/Entrez ID	MIMAT0005874	26994
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	CGI-123//SID1669

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-548e-3p	rs769297931 chr10:110988991    A/G rs781488457 chr10:110988993    T/G rs1397464360 chr10:110988983    CTG/C rs757675346 chr10:110988982    A/G

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	RNF11	chr1:51717592(+) A-I      intronic chr1:51719097(+) A-I      intronic chr1:51717564(+) A-I      intronic chr1:51737145(+) A-I      3'UTR chr1:51719084(+) A-I      intronic chr1:51712543(+) A-I      intronic chr1:51712089(+) A-I      intronic chr1:51733506(+) A-I      intronic chr1:51717600(+) A-I      intronic chr1:51717599(+) A-I      intronic chr1:51712085(+) A-I      intronic chr1:51711325(+) A-I      intronic chr1:51719101(+) A-I      intronic chr1:51719120(+) A-I      intronic chr1:51733555(+) A-I      intronic chr1:51733574(+) A-I      intronic chr1:51733586(+) A-I      intronic chr1:51720397(+) A-I      intronic chr1:51735319(+) A-I      intronic chr1:51735048(+) A-I      intronic chr1:51733683(+) A-I      intronic chr1:51733520(+) A-I      intronic chr1:51733482(+) A-I      intronic chr1:51732754(+) A-I      intronic chr1:51731617(+) A-I      intronic chr1:51729892(+) A-I      intronic chr1:51729881(+) A-I      intronic chr1:51729866(+) A-I      intronic chr1:51729697(+) A-I      intronic chr1:51727666(+) A-I      intronic chr1:51721071(+) A-I      intronic chr1:51721049(+) A-I      intronic chr1:51720417(+) A-I      intronic chr1:51720409(+) A-I      intronic chr1:51720398(+) A-I      intronic chr1:51720396(+) A-I      intronic chr1:51720382(+) A-I      intronic chr1:51720260(+) A-I      intronic chr1:51719542(+) A-I      intronic chr1:51719091(+) A-I      intronic chr1:51718707(+) A-I      intronic chr1:51718624(+) A-I      intronic chr1:51718554(+) A-I      intronic chr1:51718197(+) A-I      intronic chr1:51718109(+) A-I      intronic chr1:51717671(+) A-I      intronic chr1:51717647(+) A-I      intronic chr1:51717644(+) A-I      intronic chr1:51717640(+) A-I      intronic chr1:51717631(+) A-I      intronic chr1:51717591(+) A-I      intronic chr1:51717589(+) A-I      intronic chr1:51718592(+) A-I      intronic chr1:51712090(+) A-I      intronic chr1:51712048(+) A-I      intronic chr1:51711839(+) A-I      intronic chr1:51711826(+) A-I      intronic chr1:51711806(+) A-I      intronic chr1:51711758(+) A-I      intronic chr1:51711754(+) A-I      intronic chr1:51711752(+) A-I      intronic chr1:51711383(+) A-I      intronic chr1:51711224(+) A-I      intronic chr1:51711086(+) A-I      intronic chr1:51709272(+) A-I      intronic chr1:51709250(+) A-I      intronic chr1:51705348(+) A-I      intronic chr1:51712988(+) A-I      intronic chr1:51717552(+) A-I      intronic chr1:51717565(+) A-I      intronic chr1:51712151(+) A-I      intronic chr1:51712148(+) A-I      intronic chr1:51712251(+) A-I      intronic chr1:51712267(+) A-I      intronic chr1:51712552(+) A-I      intronic chr1:51709240(+) A-I      intronic chr1:51727710(+) A-I      intronic chr1:51712965(+) A-I      intronic chr1:51706877(+) A-I      intronic chr1:51733421(+) A-I      intronic chr1:51710764(+) A-I      intronic chr1:51711253(+) A-I      intronic chr1:51709339(+) A-I      intronic chr1:51719528(+) A-I      intronic chr1:51711761(+) A-I      intronic chr1:51711308(+) A-I      intronic chr1:51719134(+) A-I      intronic chr1:51718981(+) A-I      intronic chr1:51711045(+) A-I      intronic chr1:51719596(+) A-I      intronic chr1:51729693(+) A-I      intronic chr1:51715003(+) A-I      intronic chr1:51729692(+) A-I      intronic chr1:51708349(+) A-I      intronic chr1:51732826(+) A-I      intronic chr1:51712100(+) A-I      intronic chr1:51727312(+) A-I      intronic chr1:51732791(+) A-I      intronic chr1:51721018(+) A-I      intronic chr1:51713193(+) A-I      intronic chr1:51729882(+) A-I      intronic chr1:51711887(+) A-I      intronic chr1:51721019(+) A-I      intronic chr1:51711322(+) A-I      intronic chr1:51711270(+) A-I      intronic chr1:51711780(+) A-I      intronic chr1:51712347(+) A-I      intronic chr1:51736171(+) A-I      intronic chr1:51711027(+) A-I      intronic chr1:51730945(+) A-I      intronic chr1:51713158(+) A-I      intronic chr1:51732761(+) A-I      intronic chr1:51712547(+) A-I      intronic chr1:51712982(+) A-I      intronic chr1:51712273(+) A-I      intronic chr1:51712575(+) A-I      intronic chr1:51727692(+) A-I      intronic chr1:51712570(+) A-I      intronic chr1:51729648(+) A-I      intronic chr1:51714058(+) A-I      intronic chr1:51721097(+) A-I      intronic chr1:51721061(+) A-I      intronic chr1:51711858(+) A-I      intronic chr1:51731604(+) A-I      intronic chr1:51718091(+) A-I      intronic chr1:51720261(+) A-I      intronic chr1:51733456(+) A-I      intronic chr1:51732758(+) A-I      intronic chr1:51710881(+) A-I      intronic chr1:51714981(+) A-I      intronic chr1:51711666(+) A-I      intronic chr1:51711986(+) A-I      intronic chr1:51713005(+) A-I      intronic chr1:51709313(+) A-I      intronic chr1:51728283(+) A-I      intronic chr1:51712014(+) A-I      intronic chr1:51717658(+) A-I      intronic chr1:51736134(+) A-I      intronic chr1:51711087(+) A-I      intronic chr1:51712116(+) A-I      intronic chr1:51717518(+) A-I      intronic chr1:51732772(+) A-I      intronic chr1:51733542(+) A-I      intronic chr1:51711682(+) A-I      intronic chr1:51718678(+) A-I      intronic chr1:51731593(+) A-I      intronic chr1:51719535(+) A-I      intronic chr1:51719052(+) A-I      intronic chr1:51712274(+) A-I      intronic chr1:51720370(+) A-I      intronic chr1:51710897(+) A-I      intronic chr1:51733583(+) A-I      intronic chr1:51712338(+) A-I      intronic chr1:51719158(+) A-I      intronic chr1:51711025(+) A-I      intronic chr1:51736165(+) A-I      intronic chr1:51730946(+) A-I      intronic chr1:51727761(+) A-I      intronic chr1:51732800(+) A-I      intronic chr1:51729907(+) A-I      intronic chr1:51717699(+) A-I      intronic chr1:51711384(+) A-I      intronic chr1:51732748(+) A-I      intronic chr1:51717590(+) A-I      intronic chr1:51717478(+) A-I      intronic chr1:51721020(+) A-I      intronic chr1:51732839(+) A-I      intronic chr1:51721098(+) A-I      intronic chr1:51728697(+) A-I      intronic chr1:51718628(+) A-I      intronic chr1:51718703(+) A-I      intronic chr1:51732784(+) A-I      intronic chr1:51718638(+) A-I      intronic chr1:51717617(+) A-I      intronic chr1:51732836(+) A-I      intronic chr1:51717345(+) A-I      intronic chr1:51727644(+) A-I      intronic chr1:51708056(+) A-I      intronic chr1:51729832(+) A-I      intronic chr1:51708382(+) A-I      intronic chr1:51719048(+) A-I      intronic chr1:51711676(+) A-I      intronic chr1:51706954(+) A-I      intronic chr1:51712957(+) A-I      intronic chr1:51718681(+) A-I      intronic chr1:51711683(+) A-I      intronic chr1:51712150(+) A-I      intronic chr1:51717704(+) A-I      intronic chr1:51711756(+) A-I      intronic chr1:51733532(+) A-I      intronic chr1:51714964(+) A-I      intronic chr1:51712126(+) A-I      intronic chr1:51713017(+) A-I      intronic chr1:51711263(+) A-I      intronic chr1:51712565(+) A-I      intronic chr1:51712908(+) A-I      intronic chr1:51712668(+) A-I      intronic chr1:51719110(+) A-I      intronic chr1:51735042(+) A-I      intronic chr1:51719074(+) A-I      intronic chr1:51720268(+) A-I      intronic chr1:51727501(+) A-I      intronic chr1:51735047(+) A-I      intronic chr1:51729818(+) A-I      intronic chr1:51735028(+) A-I      intronic chr1:51711699(+) A-I      intronic chr1:51732790(+) A-I      intronic chr1:51711790(+) A-I      intronic chr1:51711817(+) A-I      intronic chr1:51717586(+) A-I      intronic chr1:51712184(+) A-I      intronic chr1:51719013(+) A-I      intronic chr1:51720264(+) A-I      intronic chr1:51718625(+) A-I      intronic chr1:51729808(+) A-I      intronic chr1:51712144(+) A-I      intronic chr1:51718964(+) A-I      intronic chr1:51728263(+) A-I      intronic chr1:51719600(+) A-I      intronic chr1:51735023(+) A-I      intronic chr1:51733451(+) A-I      intronic chr1:51713027(+) A-I      intronic chr1:51712065(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	RNF11	chr1:51719596(+) A-I intron -    21960545 chr1:51704443(+) C-A intron -    22484847 chr1:51708349(+) A-G intron -    22484847 chr1:51710881(+) A-G intron -    22484847 chr1:51711025(+) A-G intron -    22484847 chr1:51711027(+) A-G intron -    22484847 chr1:51711045(+) A-G intron -    22484847 chr1:51711253(+) A-G intron -    22484847 chr1:51711263(+) A-G intron -    22484847 chr1:51711270(+) A-G intron -    22484847 chr1:51711308(+) A-G intron -    22484847 chr1:51711322(+) A-G intron -    22484847 chr1:51711384(+) A-G intron -    22484847 chr1:51711676(+) A-G intron -    22484847 chr1:51711682(+) A-G intron -    22484847 chr1:51711683(+) A-G intron -    22484847 chr1:51711756(+) A-G intron -    22484847 chr1:51711817(+) A-G intron -    22484847 chr1:51711887(+) A-G intron -    22484847 chr1:51711986(+) A-G intron -    22484847 chr1:51712100(+) A-G intron -    22484847 chr1:51712126(+) A-G intron -    22484847 chr1:51712273(+) A-G intron -    22484847 chr1:51712338(+) A-G intron -    22484847 chr1:51712347(+) A-G intron -    22484847 chr1:51713126(+) G-T intron -    22484847 chr1:51713158(+) A-G intron -    22484847 chr1:51713193(+) A-G intron -    22484847 chr1:51715003(+) A-G intron -    22484847 chr1:51717478(+) A-G intron -    22484847 chr1:51719528(+) A-G intron -    22484847 chr1:51719535(+) A-G intron -    22484847 chr1:51720261(+) A-G intron -    22484847 chr1:51720264(+) A-G intron -    22484847 chr1:51720268(+) A-G intron -    22484847 chr1:51727501(+) A-G intron -    22484847 chr1:51727761(+) A-G intron -    22484847 chr1:51730887(+) A-G intron -    22484847 chr1:51730945(+) A-G intron -    22484847 chr1:51730946(+) A-G intron -    22484847 chr1:51731593(+) A-G intron -    22484847 chr1:51732658(+) A-G intron -    22484847 chr1:51732748(+) A-G intron -    22484847 chr1:51732772(+) A-G intron -    22484847 chr1:51732784(+) A-G intron -    22484847 chr1:51732791(+) A-G intron -    22484847 chr1:51732826(+) A-G intron -    22484847 chr1:51732836(+) A-G intron -    22484847 chr1:51733542(+) A-G intron -    22484847 chr1:51733583(+) A-G intron -    22484847 chr1:51735023(+) A-G intron -    22484847 chr1:51735047(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	RNF11	chr1:51702358-51702359(+) m6A 5'UTR//exon       24284625//24981863 chr1:51702435-51702436(+) m6A CDS//exon       24284625 chr1:51735629-51735630(+) m6A CDS//exon//intron       24284625 chr1:51735669-51735670(+) m6A CDS//exon//intron       24284625//24209618//24981863//22608085 chr1:51735701-51735702(+) m6A CDS//exon//intron       24284625//24209618//24981863//22575960//22608085 chr1:51736842-51736843(+) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr1:51736857-51736858(+) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr1:51736899-51736900(+) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr1:51736985-51736986(+) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr1:51737023-51737024(+) m6A 3'UTR//exon       24284625//24209618//24981863//22575960//22608085 chr1:51738507-51738508(+) m6A 3'UTR       27773535 chr1:51738643-51738644(+) m6A 3'UTR       27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-548e-3p	Exosome Plasma     23663360 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
	RNF11	Chromatin K562 cells     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells|K562 cells     - Ribosome-free cytosol Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-548e-3p
Interactor2: RNF11

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.