Basic Information:

  VIRBase ID:  

HHID00068885

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-320c:  MIMAT0005793          LMBR1:  NR_146958     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-320c	LMBR1
miRBase Accession/Entrez ID	MIMAT0005793	64327
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	ACHP//C7orf2//DIF14//LSS//PPD2//THYP//TPT//ZRS

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-320c	rs1240746422 chr18:21683578    T/TAAAA rs1280160499 chr18:21683572    A/G rs1443511707 chr18:21683574    AGGGT/A rs772189670 chr18:21683576    G/T rs778052898 chr18:21683578    T/C rs1285199699 chr18:24321732    G/A rs1285199699 chr18:24321732    G/C rs748073401 chr18:24321734    G/A rs756244906 chr18:24321728    G/A rs769415707 chr18:24321724    G/C rs769415707 chr18:24321724    G/T rs780317956 chr18:24321733    G/A rs958657957 chr18:24321725    G/A rs991776304 chr18:24321726    T/C rs1344472820 chr18:21683563    G/A rs748166297 chr18:21683564    C/G rs751288880 chr18:21683557    GGAAAA/G rs1159517960 chr18:24321717    A/G rs1327994455 chr18:24321720    G/A

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	LMBR1	chr7:156502710(-) A-I      intronic chr7:156502696(-) A-I      intronic chr7:156487800(-) A-I      intronic chr7:156487799(-) A-I      intronic chr7:156580883(-) A-I      intronic chr7:156633543(-) A-I      intronic chr7:156580653(-) A-I      intronic chr7:156505496(-) A-I      intronic chr7:156580650(-) A-I      intronic chr7:156580641(-) A-I      intronic chr7:156580638(-) A-I      intronic chr7:156636902(-) A-I      intronic chr7:156636906(-) A-I      intronic chr7:156638971(-) A-I      intronic chr7:156648749(-) A-I      intronic chr7:156660706(-) A-I      intronic chr7:156660948(-) A-I      intronic chr7:156660999(-) A-I      intronic chr7:156580635(-) A-I      intronic chr7:156575963(-) A-I      intronic chr7:156575958(-) A-I      intronic chr7:156575948(-) A-I      intronic chr7:156525575(-) A-I      intronic chr7:156575494(-) A-I      intronic chr7:156575273(-) A-I      intronic chr7:156567480(-) A-I      intronic chr7:156563004(-) A-I      intronic chr7:156562963(-) A-I      intronic chr7:156661602(-) A-I      intronic chr7:156525831(-) A-I      intronic chr7:156525590(-) A-I      intronic chr7:156562950(-) A-I      intronic chr7:156673602(-) A-I      intronic chr7:156673550(-) A-I      intronic chr7:156673529(-) A-I      intronic chr7:156549756(-) A-I      intronic chr7:156549689(-) A-I      intronic chr7:156542552(-) A-I      intronic chr7:156542551(-) A-I      intronic chr7:156525833(-) A-I      intronic chr7:156636467(-) A-I      intronic chr7:156673526(-) A-I      intronic chr7:156673525(-) A-I      intronic chr7:156673439(-) A-I      intronic chr7:156672246(-) A-I      intronic chr7:156672236(-) A-I      intronic chr7:156672191(-) A-I      intronic chr7:156661564(-) A-I      intronic chr7:156661008(-) A-I      intronic chr7:156580163(-) A-I      intronic chr7:156580175(-) A-I      intronic chr7:156580178(-) A-I      intronic chr7:156683790(-) A-I      intronic chr7:156580724(-) A-I      intronic chr7:156633537(-) A-I      intronic chr7:156617431(-) A-I      intronic chr7:156617364(-) A-I      intronic chr7:156608972(-) A-I      intronic chr7:156608968(-) A-I      intronic chr7:156525825(-) A-I      intronic chr7:156525633(-) A-I      intronic chr7:156522339(-) A-I      intronic chr7:156522279(-) A-I      intronic chr7:156522264(-) A-I      intronic chr7:156521765(-) A-I      intronic chr7:156521694(-) A-I      intronic chr7:156521682(-) A-I      intronic chr7:156521666(-) A-I      intronic chr7:156511345(-) A-I      intronic chr7:156511336(-) A-I      intronic chr7:156511280(-) A-I      intronic chr7:156503999(-) A-I      intronic chr7:156503921(-) A-I      intronic chr7:156503840(-) A-I      intronic chr7:156503831(-) A-I      intronic chr7:156503815(-) A-I      intronic chr7:156608895(-) A-I      intronic chr7:156607790(-) A-I      intronic chr7:156607774(-) A-I      intronic chr7:156607666(-) A-I      intronic chr7:156604216(-) A-I      intronic chr7:156603709(-) A-I      intronic chr7:156603708(-) A-I      intronic chr7:156603193(-) A-I      intronic chr7:156603192(-) A-I      intronic chr7:156680860(-) A-I      intronic chr7:156681102(-) A-I      intronic chr7:156603172(-) A-I      intronic chr7:156581660(-) A-I      intronic chr7:156581633(-) A-I      intronic chr7:156580899(-) A-I      intronic chr7:156503783(-) A-I      intronic chr7:156502763(-) A-I      intronic chr7:156502755(-) A-I      intronic chr7:156502718(-) A-I      intronic chr7:156607639(-) A-I      intronic chr7:156607787(-) A-I      intronic chr7:156661219(-) A-I      intronic chr7:156522296(-) A-I      intronic chr7:156562986(-) A-I      intronic chr7:156683628(-) A-I      intronic chr7:156522332(-) A-I      intronic chr7:156580631(-) A-I      intronic chr7:156581634(-) A-I      intronic chr7:156580961(-) A-I      intronic chr7:156581630(-) A-I      intronic chr7:156680982(-) A-I      intronic chr7:156681041(-) A-I      intronic chr7:156681057(-) A-I      intronic chr7:156680937(-) A-I      intronic chr7:156609040(-) A-I      intronic chr7:156680946(-) A-I      intronic chr7:156609038(-) A-I      intronic chr7:156521757(-) A-I      intronic chr7:156525672(-) A-I      intronic chr7:156588490(-) A-I      intronic chr7:156525593(-) A-I      intronic chr7:156521569(-) A-I      intronic chr7:156680992(-) A-I      intronic chr7:156603163(-) A-I      intronic chr7:156563436(-) A-I      intronic chr7:156525634(-) A-I      intronic chr7:156680960(-) A-I      intronic chr7:156680915(-) A-I      intronic chr7:156633464(-) A-I      intronic chr7:156605889(-) A-I      intronic chr7:156604182(-) A-I      intronic chr7:156525655(-) A-I      intronic chr7:156680940(-) A-I      intronic chr7:156502845(-) A-I      intronic chr7:156609069(-) A-I      intronic chr7:156616697(-) A-I      intronic chr7:156609037(-) A-I      intronic chr7:156522362(-) A-I      intronic chr7:156523567(-) A-I      intronic chr7:156580705(-) A-I      intronic chr7:156509771(-) A-I      intronic chr7:156561025(-) A-I      intronic chr7:156618811(-) A-I      intronic chr7:156661313(-) A-I      intronic chr7:156603678(-) A-I      intronic chr7:156521562(-) A-I      intronic chr7:156522439(-) A-I      intronic chr7:156631946(-) A-I      intronic chr7:156560801(-) A-I      intronic chr7:156502794(-) A-I      intronic chr7:156486965(-) A-I      intronic chr7:156673484(-) A-I      intronic chr7:156521810(-) A-I      intronic chr7:156603669(-) A-I      intronic chr7:156523578(-) A-I      intronic chr7:156629761(-) A-I      intronic chr7:156661025(-) A-I      intronic chr7:156661244(-) A-I      intronic chr7:156604256(-) A-I      intronic chr7:156521797(-) A-I      intronic chr7:156525800(-) A-I      intronic chr7:156560975(-) A-I      intronic chr7:156661195(-) A-I      intronic chr7:156605854(-) A-I      intronic chr7:156502737(-) A-I      intronic chr7:156672169(-) A-I      intronic chr7:156511428(-) A-I      intronic chr7:156604221(-) A-I      intronic chr7:156507828(-) A-I      intronic chr7:156630731(-) A-I      intronic chr7:156607634(-) A-I      intronic chr7:156521824(-) A-I      intronic chr7:156502836(-) A-I      intronic chr7:156541258(-) A-I      intronic chr7:156607630(-) A-I      intronic chr7:156651691(-) A-I      intronic chr7:156521672(-) A-I      intronic chr7:156660985(-) A-I      intronic chr7:156638957(-) A-I      intronic chr7:156507724(-) A-I      intronic chr7:156549690(-) A-I      intronic chr7:156617508(-) A-I      intronic chr7:156567940(-) A-I      intronic chr7:156525808(-) A-I      intronic chr7:156638417(-) A-I      intronic chr7:156569693(-) A-I      intronic chr7:156680071(-) A-I      intronic chr7:156646608(-) A-I      intronic chr7:156660990(-) A-I      intronic chr7:156605895(-) A-I      intronic chr7:156549791(-) A-I      intronic chr7:156631947(-) A-I      intronic chr7:156521737(-) A-I      intronic chr7:156525727(-) A-I      intronic chr7:156604191(-) A-I      intronic chr7:156503928(-) A-I      intronic chr7:156577924(-) A-I      intronic chr7:156588363(-) A-I      intronic chr7:156580960(-) A-I      intronic chr7:156521570(-) A-I      intronic chr7:156522448(-) A-I      intronic chr7:156569715(-) A-I      intronic chr7:156607767(-) A-I      intronic chr7:156580911(-) A-I      intronic chr7:156523548(-) A-I      intronic chr7:156502833(-) A-I      intronic chr7:156521793(-) A-I      intronic chr7:156680075(-) A-I      intronic chr7:156523376(-) A-I      intronic chr7:156503837(-) A-I      intronic chr7:156580743(-) A-I      intronic chr7:156503941(-) A-I      intronic chr7:156609064(-) A-I      intronic chr7:156509738(-) A-I      intronic chr7:156487887(-) A-I      intronic chr7:156638386(-) A-I      intronic chr7:156525635(-) A-I      intronic chr7:156661048(-) A-I      intronic chr7:156554571(-) A-I      intronic chr7:156603579(-) A-I      intronic chr7:156608996(-) A-I      intronic chr7:156661281(-) A-I      intronic chr7:156580959(-) A-I      intronic chr7:156549693(-) A-I      intronic chr7:156607768(-) A-I      intronic chr7:156542602(-) A-I      intronic chr7:156503895(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	LMBR1	chr7:156680915(-) A-I intron -    22028664 chr7:156680937(-) A-I intron -    22028664 chr7:156680940(-) A-I intron -    22028664 chr7:156680946(-) A-I intron -    22028664 chr7:156680960(-) A-I intron -    22028664 chr7:156680982(-) A-I intron -    22028664 chr7:156680992(-) A-I intron -    22028664 chr7:156681041(-) A-I intron -    22028664 chr7:156681057(-) A-I intron -    22028664 chr7:156505306(-) A-G intron -    22484847 chr7:156512927(-) A-G intron -    22484847 chr7:156631346(-) A-G intron -    22484847 chr7:156487996(-) A-G intron -    22484847 chr7:156502836(-) A-G intron -    22484847 chr7:156502845(-) A-G intron -    22484847 chr7:156503837(-) A-G intron -    22484847 chr7:156503895(-) A-G intron -    22484847 chr7:156503928(-) A-G intron -    22484847 chr7:156509771(-) A-G intron -    22484847 chr7:156521569(-) A-G intron -    22484847 chr7:156521570(-) A-G intron -    22484847 chr7:156521662(-) A-G intron -    22484847 chr7:156521672(-) A-G intron -    22484847 chr7:156521737(-) A-G intron -    22484847 chr7:156521757(-) A-G intron -    22484847 chr7:156521824(-) A-G intron -    22484847 chr7:156522306(-) A-G intron -    22484847 chr7:156522332(-) A-G intron -    22484847 chr7:156522362(-) A-G intron -    22484847 chr7:156525800(-) A-G intron -    22484847 chr7:156525808(-) A-G intron -    22484847 chr7:156542602(-) A-G intron -    22484847 chr7:156542620(-) A-G intron -    22484847 chr7:156549693(-) A-G intron -    22484847 chr7:156549713(-) A-G intron -    22484847 chr7:156554571(-) A-G intron -    22484847 chr7:156554670(-) G-T intron -    22484847 chr7:156563436(-) A-G intron -    22484847 chr7:156580631(-) A-G intron -    22484847 chr7:156580643(-) T-C intron -    22484847 chr7:156580677(-) G-C intron -    22484847 chr7:156580705(-) A-G intron -    22484847 chr7:156580718(-) A-G intron -    22484847 chr7:156580743(-) A-G intron -    22484847 chr7:156580763(-) A-G intron -    22484847 chr7:156580908(-) A-G intron -    22484847 chr7:156580911(-) A-G intron -    22484847 chr7:156580959(-) A-G intron -    22484847 chr7:156580960(-) A-G intron -    22484847 chr7:156581630(-) A-G intron -    22484847 chr7:156581634(-) A-G intron -    22484847 chr7:156581735(-) A-G intron -    22484847 chr7:156588490(-) A-G intron -    22484847 chr7:156603669(-) A-G intron -    22484847 chr7:156603674(-) A-G intron -    22484847 chr7:156604191(-) A-G intron -    22484847 chr7:156604221(-) A-G intron -    22484847 chr7:156604256(-) A-G intron -    22484847 chr7:156607728(-) A-G intron -    22484847 chr7:156607767(-) A-G intron -    22484847 chr7:156607768(-) A-G intron -    22484847 chr7:156607787(-) A-G intron -    22484847 chr7:156608976(-) A-G intron -    22484847 chr7:156608997(-) A-G intron -    22484847 chr7:156609064(-) A-G intron -    22484847 chr7:156616595(-) A-G intron -    22484847 chr7:156616697(-) A-G intron -    22484847 chr7:156618811(-) A-G intron -    22484847 chr7:156631946(-) A-G intron -    22484847 chr7:156631947(-) A-G intron -    22484847 chr7:156638386(-) A-G intron -    22484847 chr7:156638957(-) A-G intron -    22484847 chr7:156646543(-) G-A intron -    22484847 chr7:156659400(-) T-A intron -    22484847 chr7:156660985(-) A-G intron -    22484847 chr7:156660990(-) A-G intron -    22484847 chr7:156661281(-) A-G intron -    22484847 chr7:156661348(-) A-G intron -    22484847 chr7:156672169(-) A-G intron -    22484847 chr7:156673484(-) A-G intron -    22484847 chr7:156673485(-) A-G intron -    22484847 chr7:156673620(-) A-G intron -    22484847 chr7:156680071(-) A-G intron -    22484847 chr7:156680075(-) A-G intron -    22484847 chr7:156680082(-) C-T intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	LMBR1	chr7:156461776-156461777(-) m6A exon       27773535 chr7:156461915-156461916(-) m6A exon       27371828 chr7:156461945-156461946(-) m6A exon       27371828//22608085 chr7:156469005-156469006(-) m6A exon//intron       24284625//25456834//24981863//27371828//27773536//22608085 chr7:156469020-156469021(-) m6A exon//intron       24284625//25456834//24981863//27371828//27773536//22608085 chr7:156469035-156469036(-) m6A exon//intron       24284625//25456834//24981863//27371828//27773536//22608085 chr7:156469047-156469048(-) m6A exon//intron       24284625//25456834//24981863//27371828//27773536//22608085 chr7:156469220-156469221(-) m6A exon       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085 chr7:156469235-156469236(-) m6A exon       24284625//24209618//25456834//24981863//27371828//27773536//22608085 chr7:156469249-156469250(-) m6A exon       24284625//24209618//25456834//24981863//27371828//27773536//22608085 chr7:156469268-156469269(-) m6A exon       24284625//24209618//25456834//24981863//27371828//27773536//22608085 chr7:156469303-156469304(-) m6A exon       24284625//24209618//25456834//24981863//27371828//27773536//22608085 chr7:156470676-156470677(-) m6A 3'UTR//exon//intron       25456834//27773535//22608085 chr7:156470716-156470717(-) m6A 3'UTR//exon//intron       27773535//22608085 chr7:156470866-156470867(-) m6A 3'UTR//exon//intron       27773535 chr7:156473034-156473035(-) m6A 3'UTR//intron       27773535 chr7:156473176-156473177(-) m6A 3'UTR//exon       27773535 chr7:156473239-156473240(-) m6A 3'UTR//exon       24284625//25456834//24981863//27773535//27773536//22608085 chr7:156473261-156473262(-) m6A 3'UTR//exon       24284625//25456834//24981863//27773535//27773536//22608085 chr7:156473266-156473267(-) m6A 3'UTR//exon       27773535//22608085 chr7:156473297-156473298(-) m6A 3'UTR//intron       22608085 chr7:156473490-156473491(-) m6A 3'UTR//intron       27773535 chr7:156474271-156474272(-) m6A 3'UTR//intron       24284625//27773535 chr7:156474451-156474452(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27773535//27371828//22608085 chr7:156474515-156474516(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085 chr7:156474570-156474571(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085 chr7:156474630-156474631(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085 chr7:156474722-156474723(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085 chr7:156474739-156474740(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr7:156474746-156474747(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085 chr7:156474854-156474855(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr7:156474911-156474912(-) m6A 3'UTR       24284625//24981863//27773535//22608085 chr7:156476423-156476424(-) m6A 3'UTR       24284625//24209618//24981863//27773535//22608085 chr7:156476431-156476432(-) m6A 3'UTR       24284625//24209618//24981863//27773535//22608085 chr7:156476511-156476512(-) m6A 3'UTR       24284625//24209618//24981863//27773535//22608085 chr7:156476530-156476531(-) m6A 3'UTR       24284625//24209618//24981863//27773535//22608085 chr7:156476539-156476540(-) m6A 3'UTR       24284625//24209618//24981863//27773535//22608085 chr7:156476576-156476577(-) m6A 3'UTR       24284625//24209618//24981863//27773535//22608085 chr7:156476619-156476620(-) m6A 3'UTR       24284625//24209618//24981863//26404942//27773535//22608085 chr7:156476657-156476658(-) m6A 3'UTR       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr7:156476663-156476664(-) m6A 3'UTR       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr7:156476730-156476731(-) m6A 3'UTR       24284625//24209618//24981863//26404942//27773535//22575960//22608085 chr7:156476738-156476739(-) m6A 3'UTR       24284625//24981863//26404942//27773535//22575960//22608085 chr7:156476812-156476813(-) m6A 3'UTR//CDS       24284625//24981863//26404942//27773535//22575960//22608085 chr7:156476846-156476847(-) m6A 3'UTR//CDS       24284625//24981863//27773535//22608085 chr7:156480739-156480740(-) m6A 3'UTR//CDS//intron       24284625 chr7:156685262-156685263(-) m6A exon//intron       27773536

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-320c	Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytoplasm Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059 Exosome Pooled sera     27278097 Exosome Breast cancer cell line (MCF-7)     20976003 Exosome Ovarian follicular fluid     22116803 Exosome Plasma     23663360 Exosome Colon cancer cell line (LIM1863)     25330373 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Plasma     23077538 Microvesicle Seminal plasma     23539611 Microvesicle Serum     24797360 Microvesicle Fibroblasts|Mesenchymal stem cells|Urine     - Mitochondrion Cell line (HEK-293|HeLa)     22984580 Nucleus Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059 Nucleus Nasopharyngeal carcinoma cells     20498841
	LMBR1	Chromatin HCC cell line (HepG2)|K562 cells     - Cytosol K562 cells     - Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Insoluble cytoplasm K562 cells     - Membrane HCC cell line (HepG2)|K562 cells     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-320c
Interactor2: LMBR1

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.