Basic Information:

  VIRBase ID:  

HHID00068828

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-320c:  MIMAT0005793          EVI2A:  NM_001003927     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-320c	EVI2A
miRBase Accession/Entrez ID	MIMAT0005793	2123
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	EVDA//EVI-2A//EVI2

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-320c	rs1240746422 chr18:21683578    T/TAAAA rs1280160499 chr18:21683572    A/G rs1443511707 chr18:21683574    AGGGT/A rs772189670 chr18:21683576    G/T rs778052898 chr18:21683578    T/C rs1285199699 chr18:24321732    G/A rs1285199699 chr18:24321732    G/C rs748073401 chr18:24321734    G/A rs756244906 chr18:24321728    G/A rs769415707 chr18:24321724    G/C rs769415707 chr18:24321724    G/T rs780317956 chr18:24321733    G/A rs958657957 chr18:24321725    G/A rs991776304 chr18:24321726    T/C rs1344472820 chr18:21683563    G/A rs748166297 chr18:21683564    C/G rs751288880 chr18:21683557    GGAAAA/G rs1159517960 chr18:24321717    A/G rs1327994455 chr18:24321720    G/A

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	EVI2A	chr17:29644968-29644969(-) m6A 3'UTR       26404942 chr17:29645057-29645058(-) m6A 3'UTR       26404942 chr17:29645150-29645151(-) m6A 3'UTR       26404942 chr17:29645182-29645183(-) m6A 3'UTR       26404942 chr17:29645211-29645212(-) m6A 3'UTR       26404942 chr17:29645332-29645333(-) m6A CDS       28052920//26404942//27371828 chr17:29645344-29645345(-) m6A CDS       28052920//26404942//27371828 chr17:29645352-29645353(-) m6A CDS       28052920//26404942//27371828 chr17:29645419-29645420(-) m6A CDS       28052920//26404942//27371828 chr17:29645431-29645432(-) m6A CDS       28052920//26404942//27371828 chr17:29645436-29645437(-) m6A CDS       28052920//26404942//27371828 chr17:29645450-29645451(-) m6A CDS       28052920//26404942//27371828 chr17:29645521-29645522(-) m6A CDS       28052920//26404942//27371828 chr17:29645549-29645550(-) m6A CDS       28052920//26404942//27371828 chr17:29645645-29645646(-) m6A CDS       26404942 chr17:29645696-29645697(-) m6A CDS       26404942 chr17:29645758-29645759(-) m6A CDS       26404942 chr17:29645793-29645794(-) m6A CDS       28052920//26404942 chr17:29645804-29645805(-) m6A CDS       28052920//26404942 chr17:29645846-29645847(-) m6A CDS       28052920//26404942 chr17:29645858-29645859(-) m6A CDS       28052920//26404942 chr17:29645870-29645871(-) m6A CDS       28052920//26404942 chr17:29645880-29645881(-) m6A CDS       28052920//26404942 chr17:29645885-29645886(-) m6A CDS       28052920//26404942 chr17:29645939-29645940(-) m6A CDS       28052920//26404942//27371828 chr17:29645949-29645950(-) m6A CDS       28052920//26404942//27371828 chr17:29646004-29646005(-) m6A CDS       26404942 chr17:29646013-29646014(-) m6A CDS       26404942 chr17:29646020-29646021(-) m6A CDS       26404942 chr17:29647417-29647418(-) m6A CDS//intron       26404942 chr17:29647423-29647424(-) m6A CDS//intron       26404942 chr17:29647485-29647486(-) m6A 5'UTR//intron       - chr17:29648006-29648007(-) m6A 5'UTR//intron       26404942 chr17:29648575-29648576(-) m6A 5'UTR       26404942 chr17:29648655-29648656(-) m6A 5'UTR       26404942

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-320c	Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytoplasm Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059 Exosome Pooled sera     27278097 Exosome Breast cancer cell line (MCF-7)     20976003 Exosome Ovarian follicular fluid     22116803 Exosome Plasma     23663360 Exosome Colon cancer cell line (LIM1863)     25330373 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Plasma     23077538 Microvesicle Seminal plasma     23539611 Microvesicle Serum     24797360 Microvesicle Fibroblasts|Mesenchymal stem cells|Urine     - Mitochondrion Cell line (HEK-293|HeLa)     22984580 Nucleus Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059 Nucleus Nasopharyngeal carcinoma cells     20498841
	EVI2A	Exosome Blood     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-320c
Interactor2: EVI2A

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	CDS
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.