Basic Information:

  VIRBase ID:  

HHID00068817

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-320b:  MIMAT0005792          NRROS:  NM_198565     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-320b	NRROS
miRBase Accession/Entrez ID	MIMAT0005792	375387
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	ELLP3030//GARPL1//LRRC33//SENEBAC//UNQ3030

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-320b	rs1156276707 chr1:116671796    G/T rs1311857670 chr1:116671805    GCAAA/G rs1373244526 chr1:116671806    C/T rs1434535374 chr1:116671803    G/C rs755613466 chr1:116671797    T/C rs779451916 chr1:116671801    G/C rs1303311077 chr1:224257059    A/T rs1313950455 chr1:224257062    C/A rs1333032274 chr1:224257051    G/T rs1445839645 chr1:224257055    T/C rs1465806287 chr1:224257050    TGCCC/T rs745315768 chr1:224257052    C/T rs769446888 chr1:224257054    C/T rs1189118293 chr1:116671788    A/G rs1199375375 chr1:116671794    G/A rs1411861918 chr1:116671791    G/T rs1469116635 chr1:116671792    C/CTGGGTTGAGAGGGCAAACAAATTAACTAAT rs1030808536 chr1:224257064    A/T rs774951709 chr1:224257069    T/C

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	NRROS	chr3:196385582(+) A-I      intronic chr3:196375374(+) A-I      intronic chr3:196375418(+) A-I      intronic chr3:196375454(+) A-I      intronic chr3:196386414(+) A-I      intronic chr3:196386423(+) A-I      intronic chr3:196374639(+) A-I      intronic chr3:196375494(+) A-I      intronic chr3:196375517(+) A-I      intronic chr3:196374596(+) A-I      intronic chr3:196374491(+) A-I      intronic chr3:196369821(+) A-I      intronic chr3:196377042(+) A-I      intronic chr3:196369820(+) A-I      intronic chr3:196369811(+) A-I      intronic chr3:196369688(+) A-I      intronic chr3:196368275(+) A-I      intronic chr3:196368223(+) A-I      intronic chr3:196368102(+) A-I      intronic chr3:196386460(+) A-I      intronic chr3:196374650(+) A-I      intronic chr3:196375530(+) A-I      intronic chr3:196375579(+) A-I      intronic chr3:196377180(+) A-I      intronic chr3:196377181(+) A-I      intronic chr3:196377277(+) A-I      intronic chr3:196378437(+) A-I      intronic chr3:196378482(+) A-I      intronic chr3:196378518(+) A-I      intronic chr3:196384458(+) A-I      intronic chr3:196378399(+) A-I      intronic chr3:196375436(+) A-I      intronic chr3:196374531(+) A-I      intronic chr3:196386415(+) A-I      intronic chr3:196385661(+) A-I      intronic chr3:196374739(+) A-I      intronic chr3:196378517(+) A-I      intronic chr3:196386296(+) A-I      intronic chr3:196385823(+) A-I      intronic chr3:196386279(+) A-I      intronic chr3:196378491(+) A-I      intronic chr3:196377081(+) A-I      intronic chr3:196386369(+) A-I      intronic chr3:196386344(+) A-I      intronic chr3:196386363(+) A-I      intronic chr3:196377426(+) A-I      intronic chr3:196368218(+) A-I      intronic chr3:196384414(+) A-I      intronic chr3:196374453(+) A-I      intronic chr3:196385829(+) A-I      intronic chr3:196386454(+) A-I      intronic chr3:196385613(+) A-I      intronic chr3:196386354(+) A-I      intronic chr3:196385720(+) A-I      intronic chr3:196385750(+) A-I      intronic chr3:196382026(+) A-I      intronic chr3:196386280(+) A-I      intronic chr3:196374738(+) A-I      intronic chr3:196385762(+) A-I      intronic chr3:196382970(+) A-I      intronic chr3:196385628(+) A-I      intronic chr3:196378476(+) A-I      intronic chr3:196378617(+) A-I      intronic chr3:196377144(+) A-I      intronic chr3:196386283(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	NRROS	chr3:196381471-196381472(+) m6A CDS//exon       - chr3:196381482-196381483(+) m6A CDS//exon       - chr3:196386724-196386725(+) m6A CDS       - chr3:196386854-196386855(+) m6A CDS       25456834 chr3:196386872-196386873(+) m6A CDS       25456834 chr3:196386926-196386927(+) m6A CDS       25456834 chr3:196386953-196386954(+) m6A CDS       25456834 chr3:196386977-196386978(+) m6A CDS       25456834 chr3:196387013-196387014(+) m6A CDS       25456834 chr3:196387085-196387086(+) m6A CDS       - chr3:196387178-196387179(+) m6A CDS       - chr3:196387280-196387281(+) m6A CDS       25456834 chr3:196387339-196387340(+) m6A CDS       - chr3:196387379-196387380(+) m6A CDS       - chr3:196387514-196387515(+) m6A CDS       - chr3:196387526-196387527(+) m6A CDS       25456834 chr3:196387586-196387587(+) m6A CDS       25456834 chr3:196387658-196387659(+) m6A CDS       25456834 chr3:196387793-196387794(+) m6A CDS       25456834 chr3:196387856-196387857(+) m6A CDS       25456834 chr3:196387949-196387950(+) m6A CDS       25456834//24981863 chr3:196387966-196387967(+) m6A CDS       25456834//24981863 chr3:196387985-196387986(+) m6A CDS       25456834//24981863 chr3:196388072-196388073(+) m6A CDS       25456834 chr3:196388105-196388106(+) m6A CDS       25456834 chr3:196388132-196388133(+) m6A CDS       25456834 chr3:196388197-196388198(+) m6A CDS       25456834 chr3:196388216-196388217(+) m6A CDS       25456834 chr3:196388275-196388276(+) m6A CDS       25456834 chr3:196388432-196388433(+) m6A CDS       25456834 chr3:196388453-196388454(+) m6A CDS       25456834 chr3:196388610-196388611(+) m6A 3'UTR       - chr3:196388638-196388639(+) m6A 3'UTR       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-320b	Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytoplasm Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059 Exosome Pooled sera     27278097 Exosome Breast cancer cell line (MCF-7)     20976003 Exosome Ovarian follicular fluid     22116803 Exosome Plasma     23663360 Exosome Colon cancer cell line (LIM1863)     25330373 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Plasma     23077538 Microvesicle Seminal plasma     23539611 Microvesicle Hepatoma cells     23771658 Microvesicle Serum     24797360 Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine     - Mitochondrion Skeletal muscle myoblasts     21637849 Mitochondrion Cell line (HEK-293|HeLa)     22984580 Nucleus Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059 Nucleus Nasopharyngeal carcinoma cells     20498841
	NRROS	Chromatin K562 cells     - Exosome Blood     - Nucleoplasm K562 cells     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID	Function	Link
RNAInter	hsa-miR-320b	Eloxatine 5310940 Drug interaction    RC00007663 cis-Diaminedichloroplatinum 2767 Drug interaction    RC00007662 Benzene 241 Drug interaction    RC00007661 Marine fungal metabolite 1386A - Drug interaction    RC00007664

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hsa-miR-320b	Topotecan       60700

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-320b
Interactor2: NRROS

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.