Basic Information:

  VIRBase ID:  

HHID00068796

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-320b:  MIMAT0005792          FSD1L:  NM_031919     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-320b	FSD1L
miRBase Accession/Entrez ID	MIMAT0005792	83856
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	CCDC10//CSDUFD1//FSD1CL//FSD1NL//MIR1

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-320b	rs1156276707 chr1:116671796    G/T rs1311857670 chr1:116671805    GCAAA/G rs1373244526 chr1:116671806    C/T rs1434535374 chr1:116671803    G/C rs755613466 chr1:116671797    T/C rs779451916 chr1:116671801    G/C rs1303311077 chr1:224257059    A/T rs1313950455 chr1:224257062    C/A rs1333032274 chr1:224257051    G/T rs1445839645 chr1:224257055    T/C rs1465806287 chr1:224257050    TGCCC/T rs745315768 chr1:224257052    C/T rs769446888 chr1:224257054    C/T rs1189118293 chr1:116671788    A/G rs1199375375 chr1:116671794    G/A rs1411861918 chr1:116671791    G/T rs1469116635 chr1:116671792    C/CTGGGTTGAGAGGGCAAACAAATTAACTAAT rs1030808536 chr1:224257064    A/T rs774951709 chr1:224257069    T/C

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	FSD1L	chr9:108213370(+) A-I      intronic chr9:108213500(+) A-I      intronic chr9:108213501(+) A-I      intronic chr9:108213514(+) A-I      intronic chr9:108224493(+) A-I      intronic chr9:108224518(+) A-I      intronic chr9:108224548(+) A-I      intronic chr9:108224667(+) A-I      intronic chr9:108224682(+) A-I      intronic chr9:108230893(+) A-I      intronic chr9:108261085(+) A-I      intronic chr9:108261077(+) A-I      intronic chr9:108224600(+) A-I      intronic chr9:108213358(+) A-I      intronic chr9:108224597(+) A-I      intronic chr9:108224596(+) A-I      intronic chr9:108224577(+) A-I      intronic chr9:108261115(+) A-I      intronic chr9:108225039(+) A-I      intronic chr9:108224702(+) A-I      intronic chr9:108265437(+) A-I      intronic chr9:108224685(+) A-I      intronic chr9:108225272(+) A-I      intronic chr9:108225038(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	FSD1L	chr9:108284664(+) A-I intron -    22327324 chr9:108296288(+) G-A intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	FSD1L	chr9:108286524-108286525(+) m6A intron       - chr9:108286580-108286581(+) m6A intron       - chr9:108287183-108287184(+) m6A intron       24981863 chr9:108308652-108308653(+) m6A CDS       24981863 chr9:108308695-108308696(+) m6A CDS       24981863 chr9:108308744-108308745(+) m6A CDS       24981863 chr9:108308927-108308928(+) m6A 3'UTR       24981863 chr9:108308972-108308973(+) m6A 3'UTR       24981863 chr9:108309025-108309026(+) m6A 3'UTR       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-320b	Cytoplasm Nasopharyngeal carcinoma cells     20498841 Cytoplasm Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059 Exosome Pooled sera     27278097 Exosome Breast cancer cell line (MCF-7)     20976003 Exosome Ovarian follicular fluid     22116803 Exosome Plasma     23663360 Exosome Colon cancer cell line (LIM1863)     25330373 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Plasma     23077538 Microvesicle Seminal plasma     23539611 Microvesicle Hepatoma cells     23771658 Microvesicle Serum     24797360 Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine     - Mitochondrion Skeletal muscle myoblasts     21637849 Mitochondrion Cell line (HEK-293|HeLa)     22984580 Nucleus Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059 Nucleus Nasopharyngeal carcinoma cells     20498841
	FSD1L	Exosome Blood     - Membrane K562 cells     - Nucleolus K562 cells     - Nucleoplasm K562 cells     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID	Function	Link
RNAInter	hsa-miR-320b	Eloxatine 5310940 Drug interaction    RC00007663 cis-Diaminedichloroplatinum 2767 Drug interaction    RC00007662 Benzene 241 Drug interaction    RC00007661 Marine fungal metabolite 1386A - Drug interaction    RC00007664

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hsa-miR-320b	Topotecan       60700

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-320b
Interactor2: FSD1L

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.