Detail Information

Basic Information:


  VIRBase ID:  

HHID00068772

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-320b:           ACOT7:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-320b ACOT7
miRBase
Accession/Entrez ID		 MIMAT0005792 11332
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - ACH1//ACT//BACH//CTE-II//hBACH//LACH//LACH1

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-320b
rs1156276707 chr1:116671796    G/T
rs1311857670 chr1:116671805    GCAAA/G
rs1373244526 chr1:116671806    C/T
rs1434535374 chr1:116671803    G/C
rs755613466 chr1:116671797    T/C
rs779451916 chr1:116671801    G/C
rs1303311077 chr1:224257059    A/T
rs1313950455 chr1:224257062    C/A
rs1333032274 chr1:224257051    G/T
rs1445839645 chr1:224257055    T/C
rs1465806287 chr1:224257050    TGCCC/T
rs745315768 chr1:224257052    C/T
rs769446888 chr1:224257054    C/T
rs1189118293 chr1:116671788    A/G
rs1199375375 chr1:116671794    G/A
rs1411861918 chr1:116671791    G/T
rs1469116635 chr1:116671792    C/CTGGGTTGAGAGGGCAAACAAATTAACTAAT
rs1030808536 chr1:224257064    A/T
rs774951709 chr1:224257069    T/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR ACOT7
chr1:6383138(-) A-I      intronic
chr1:6353679(-) A-I      intronic
chr1:6439754(-) A-I      intronic
chr1:6429906(-) A-I      intronic
chr1:6413296(-) A-I      intronic
chr1:6427212(-) A-I      intronic
chr1:6427207(-) A-I      intronic
chr1:6427196(-) A-I      intronic
chr1:6427173(-) A-I      intronic
chr1:6413135(-) A-I      intronic
chr1:6413134(-) A-I      intronic
chr1:6413132(-) A-I      intronic
chr1:6426854(-) A-I      intronic
chr1:6426160(-) A-I      intronic
chr1:6426159(-) A-I      intronic
chr1:6426124(-) A-I      intronic
chr1:6426052(-) A-I      intronic
chr1:6425604(-) A-I      intronic
chr1:6417197(-) A-I      intronic
chr1:6417169(-) A-I      intronic
chr1:6412971(-) A-I      intronic
chr1:6416940(-) A-I      intronic
chr1:6416935(-) A-I      intronic
chr1:6413680(-) A-I      intronic
chr1:6413642(-) A-I      intronic
chr1:6413607(-) A-I      intronic
chr1:6413370(-) A-I      intronic
chr1:6413303(-) A-I      intronic
chr1:6353061(-) A-I      intronic
chr1:6347042(-) A-I      intronic
chr1:6344033(-) A-I      intronic
chr1:6413297(-) A-I      intronic
chr1:6433843(-) A-I      intronic
chr1:6413109(-) A-I      intronic
chr1:6413108(-) A-I      intronic
chr1:6448714(-) A-I      intronic
chr1:6448675(-) A-I      intronic
chr1:6448555(-) A-I      intronic
chr1:6448442(-) A-I      intronic
chr1:6448441(-) A-I      intronic
chr1:6443880(-) A-I      intronic
chr1:6443727(-) A-I      intronic
chr1:6443720(-) A-I      intronic
chr1:6442704(-) A-I      intronic
chr1:6442402(-) A-I      intronic
chr1:6442298(-) A-I      intronic
chr1:6439771(-) A-I      intronic
chr1:6436563(-) A-I      intronic
chr1:6436233(-) A-I      intronic
chr1:6436232(-) A-I      intronic
chr1:6435886(-) A-I      intronic
chr1:6435876(-) A-I      intronic
chr1:6435874(-) A-I      intronic
chr1:6433862(-) A-I      intronic
chr1:6413110(-) A-I      intronic
chr1:6433842(-) A-I      intronic
chr1:6433745(-) A-I      intronic
chr1:6433722(-) A-I      intronic
chr1:6433407(-) A-I      intronic
chr1:6431602(-) A-I      intronic
chr1:6431547(-) A-I      intronic
chr1:6431515(-) A-I      intronic
chr1:6431511(-) A-I      intronic
chr1:6388696(-) A-I      intronic
chr1:6388695(-) A-I      intronic
chr1:6388524(-) A-I      intronic
chr1:6386909(-) A-I      intronic
chr1:6386838(-) A-I      intronic
chr1:6386837(-) A-I      intronic
chr1:6386829(-) A-I      intronic
chr1:6383052(-) A-I      intronic
chr1:6382956(-) A-I      intronic
chr1:6382946(-) A-I      intronic
chr1:6381672(-) A-I      intronic
chr1:6376787(-) A-I      intronic
chr1:6353082(-) A-I      intronic
chr1:6353078(-) A-I      intronic
chr1:6430995(-) A-I      intronic
chr1:6429907(-) A-I      intronic
chr1:6450944(-) A-I      intronic
chr1:6426386(-) A-I      intronic
chr1:6343971(-) A-I      intronic
chr1:6426174(-) A-I      intronic
chr1:6353645(-) A-I      intronic
chr1:6352838(-) A-I      intronic
chr1:6401001(-) A-I      intronic
chr1:6413103(-) A-I      intronic
chr1:6352810(-) A-I      intronic
chr1:6349650(-) A-I      intronic
chr1:6388053(-) A-I      intronic
chr1:6413035(-) A-I      intronic
chr1:6353678(-) A-I      intronic
chr1:6439886(-) A-I      intronic
chr1:6429220(-) A-I      intronic
chr1:6352997(-) A-I      intronic
chr1:6353757(-) A-I      intronic
chr1:6426745(-) A-I      intronic
chr1:6442748(-) A-I      intronic
chr1:6450901(-) A-I      intronic
chr1:6433886(-) A-I      intronic
chr1:6378388(-) A-I      intronic
chr1:6378065(-) A-I      intronic
chr1:6353704(-) A-I      intronic
chr1:6435081(-) A-I      intronic
chr1:6448738(-) A-I      intronic
chr1:6352879(-) A-I      intronic
chr1:6400086(-) A-I      intronic
chr1:6387919(-) A-I      intronic
chr1:6448308(-) A-I      intronic
chr1:6349841(-) A-I      intronic
chr1:6426092(-) A-I      intronic
chr1:6426783(-) A-I      intronic
chr1:6449732(-) A-I      intronic
chr1:6383082(-) A-I      intronic
chr1:6449804(-) A-I      intronic
chr1:6429912(-) A-I      intronic
chr1:6344049(-) A-I      intronic
chr1:6413608(-) A-I      intronic
chr1:6378243(-) A-I      intronic
chr1:6353114(-) A-I      intronic
chr1:6387896(-) A-I      intronic
chr1:6436398(-) A-I      intronic
chr1:6433474(-) A-I      intronic
chr1:6442658(-) A-I      intronic
chr1:6354076(-) A-I      intronic
chr1:6344380(-) A-I      intronic
chr1:6426040(-) A-I      intronic
chr1:6353299(-) A-I      intronic
chr1:6439929(-) A-I      intronic
chr1:6353649(-) A-I      intronic
chr1:6386930(-) A-I      intronic
chr1:6426534(-) A-I      intronic
chr1:6344024(-) A-I      intronic
chr1:6353653(-) A-I      intronic
chr1:6353022(-) A-I      intronic
chr1:6440004(-) A-I      intronic
chr1:6436928(-) A-I      intronic
chr1:6413006(-) A-I      intronic
chr1:6352950(-) A-I      intronic
chr1:6401398(-) A-I      intronic
chr1:6387998(-) A-I      intronic
chr1:6448677(-) A-I      intronic
chr1:6335608(-) A-I      intronic
chr1:6424117(-) A-I      intronic
chr1:6371070(-) A-I      intronic
chr1:6430646(-) A-I      intronic
chr1:6431508(-) A-I      intronic
chr1:6382940(-) A-I      intronic
chr1:6343386(-) A-I      intronic
chr1:6401240(-) A-I      intronic
chr1:6353088(-) A-I      intronic
chr1:6343505(-) A-I      intronic
chr1:6343955(-) A-I      intronic
chr1:6440043(-) A-I      intronic
chr1:6353714(-) A-I      intronic
chr1:6353739(-) A-I      intronic
chr1:6388455(-) A-I      intronic
chr1:6344374(-) A-I      intronic
chr1:6439949(-) A-I      intronic
chr1:6432885(-) A-I      intronic
chr1:6443090(-) A-I      intronic
chr1:6442418(-) A-I      intronic
chr1:6353715(-) A-I      intronic
chr1:6413284(-) A-I      intronic
chr1:6439924(-) A-I      intronic
chr1:6443497(-) A-I      intronic
chr1:6386858(-) A-I      intronic
chr1:6426813(-) A-I      intronic
chr1:6353725(-) A-I      intronic
chr1:6388060(-) A-I      intronic
chr1:6436874(-) A-I      intronic
chr1:6446698(-) A-I      intronic
chr1:6440063(-) A-I      intronic
chr1:6378348(-) A-I      intronic
chr1:6429204(-) A-I      intronic
chr1:6400123(-) A-I      intronic
chr1:6448334(-) A-I      intronic
chr1:6443734(-) A-I      intronic
chr1:6344003(-) A-I      intronic
chr1:6432882(-) A-I      intronic
chr1:6352880(-) A-I      intronic
chr1:6432755(-) A-I      intronic
chr1:6343322(-) A-I      intronic
chr1:6343998(-) A-I      intronic
chr1:6443520(-) A-I      intronic
chr1:6382928(-) A-I      intronic
chr1:6449722(-) A-I      intronic
chr1:6439662(-) A-I      intronic
chr1:6343640(-) A-I      intronic
chr1:6426093(-) A-I      intronic
chr1:6432737(-) A-I      intronic
chr1:6439916(-) A-I      intronic
chr1:6438438(-) A-I      intronic
chr1:6426524(-) A-I      intronic
chr1:6353639(-) A-I      intronic
chr1:6383078(-) A-I      intronic
chr1:6443077(-) A-I      intronic
chr1:6343320(-) A-I      intronic
chr1:6440010(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED ACOT7
chr1:6353645(-) A-G intron -    22484847
chr1:6353653(-) A-G intron -    22484847
chr1:6353739(-) A-G intron -    22484847
chr1:6371070(-) A-G intron -    22484847
chr1:6383078(-) A-G intron -    22484847
chr1:6383082(-) A-G intron -    22484847
chr1:6387998(-) A-G intron -    22484847
chr1:6388060(-) A-G intron -    22484847
chr1:6413006(-) A-G intron -    22484847
chr1:6413103(-) A-G intron -    22484847
chr1:6413608(-) A-G intron -    22484847
chr1:6422333(-) G-T intron -    22484847
chr1:6426040(-) A-G intron -    22484847
chr1:6426092(-) A-G intron -    22484847
chr1:6426093(-) A-G intron -    22484847
chr1:6426174(-) A-G intron -    22484847
chr1:6429912(-) A-G intron -    22484847
chr1:6433886(-) A-G intron -    22484847
chr1:6436874(-) A-G intron -    22484847
chr1:6436928(-) A-G intron -    22484847
chr1:6439145(-) C-G intron -    22484847
chr1:6439886(-) A-G intron -    22484847
chr1:6439924(-) A-G intron -    22484847
chr1:6439929(-) A-G intron -    22484847
chr1:6439949(-) A-G intron -    22484847
chr1:6440004(-) A-G intron -    22484847
chr1:6440010(-) A-G intron -    22484847
chr1:6440043(-) A-G intron -    22484847
chr1:6440063(-) A-G intron -    22484847
chr1:6442418(-) A-G intron -    22484847
chr1:6442426(-) G-A intron -    22484847
chr1:6442748(-) A-G intron -    22484847
chr1:6448334(-) A-G intron -    22484847
chr1:6448738(-) A-G intron -    22484847
chr1:6449103(-) C-T intron -    22484847
chr1:6449722(-) A-G intron -    22484847
chr1:6450901(-) A-G intron -    22484847
chr1:6450944(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase ACOT7
chr1:6324568-6324569(-) m6A 3'UTR       24284625
chr1:6324655-6324656(-) m6A 3'UTR       24284625//27773536
chr1:6324748-6324749(-) m6A 3'UTR//CDS       24284625//27773536//22575960
chr1:6341255-6341256(-) m6A 3'UTR//CDS       24284625//27773535
chr1:6342871-6342872(-) m6A 3'UTR//intron       -
chr1:6366529-6366530(-) m6A intron       -
chr1:6366536-6366537(-) m6A intron       -
chr1:6366542-6366543(-) m6A intron       -
chr1:6366550-6366551(-) m6A intron       -
chr1:6378580-6378581(-) m6A CDS       24284625
chr1:6378631-6378632(-) m6A CDS       24284625//27773535
chr1:6387384-6387385(-) m6A CDS       24284625//27773535
chr1:6387403-6387404(-) m6A CDS       24284625//27773535
chr1:6409876-6409877(-) m6A CDS       24284625//27371828
chr1:6418969-6418970(-) m6A 5'UTR//intron       27371828
chr1:6418990-6418991(-) m6A 5'UTR//intron       27371828
chr1:6453415-6453416(-) m6A 5'UTR//CDS       25456834//24981863//27371828
chr1:6453668-6453669(-) m6A 5'UTR       24209618

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-320b
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Cytoplasm Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059
Exosome Pooled sera     27278097
Exosome Breast cancer cell line (MCF-7)     20976003
Exosome Ovarian follicular fluid     22116803
Exosome Plasma     23663360
Exosome Colon cancer cell line (LIM1863)     25330373
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Plasma     23077538
Microvesicle Seminal plasma     23539611
Microvesicle Hepatoma cells     23771658
Microvesicle Serum     24797360
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine     -
Mitochondrion Skeletal muscle myoblasts     21637849
Mitochondrion Cell line (HEK-293|HeLa)     22984580
Nucleus Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059
Nucleus Nasopharyngeal carcinoma cells     20498841
ACOT7
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleolus K562 cells     -
Nucleus HeLa-S3 cells     -
Ribosome HEK-293 cells     22199352
Ribosome Colon cancer cells     24393600

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-320b
Eloxatine 5310940 Drug interaction    RC00007663
cis-Diaminedichloroplatinum 2767 Drug interaction    RC00007662
Benzene 241 Drug interaction    RC00007661
Marine fungal metabolite 1386A - Drug interaction    RC00007664
Resource Symbol Drug Name PubChem ID
RNAactDrug hsa-miR-320b
Topotecan       60700

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-320b
Interactor2: ACOT7

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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