Detail Information

Basic Information:


  VIRBase ID:  

HHID00068761

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-320b:           SART3:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-320b SART3
miRBase
Accession/Entrez ID		 MIMAT0005792 9733
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - DSAP1//P100//p110//p110(nrb)//RP11-13G14//TIP110

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-320b
rs1156276707 chr1:116671796    G/T
rs1311857670 chr1:116671805    GCAAA/G
rs1373244526 chr1:116671806    C/T
rs1434535374 chr1:116671803    G/C
rs755613466 chr1:116671797    T/C
rs779451916 chr1:116671801    G/C
rs1303311077 chr1:224257059    A/T
rs1313950455 chr1:224257062    C/A
rs1333032274 chr1:224257051    G/T
rs1445839645 chr1:224257055    T/C
rs1465806287 chr1:224257050    TGCCC/T
rs745315768 chr1:224257052    C/T
rs769446888 chr1:224257054    C/T
rs1189118293 chr1:116671788    A/G
rs1199375375 chr1:116671794    G/A
rs1411861918 chr1:116671791    G/T
rs1469116635 chr1:116671792    C/CTGGGTTGAGAGGGCAAACAAATTAACTAAT
rs1030808536 chr1:224257064    A/T
rs774951709 chr1:224257069    T/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR SART3
chr12:108928332(-) A-I      intronic
chr12:108928399(-) A-I      intronic
chr12:108928370(-) A-I      intronic
chr12:108928334(-) A-I      intronic
chr12:108939557(-) A-I      intronic
chr12:108939499(-) A-I      intronic
chr12:108949319(-) A-I      intronic
chr12:108949322(-) A-I      intronic
chr12:108949341(-) A-I      intronic
chr12:108949358(-) A-I      intronic
chr12:108949405(-) A-I      intronic
chr12:108951073(-) A-I      intronic
chr12:108940719(-) A-I      intronic
chr12:108949991(-) A-I      intronic
chr12:108950006(-) A-I      intronic
chr12:108922681(-) A-I      intronic
chr12:108951675(-) A-I      intronic
chr12:108951774(-) A-I      intronic
chr12:108953276(-) A-I      intronic
chr12:108935828(-) A-I      intronic
chr12:108953190(-) A-I      intronic
chr12:108940877(-) A-I      intronic
chr12:108928344(-) A-I      intronic
chr12:108940170(-) A-I      intronic
chr12:108926626(-) A-I      intronic
chr12:108926668(-) A-I      intronic
chr12:108926658(-) A-I      intronic
chr12:108926641(-) A-I      intronic
chr12:108935912(-) A-I      intronic
chr12:108939514(-) A-I      intronic
chr12:108926613(-) A-I      intronic
chr12:108939576(-) A-I      intronic
chr12:108939593(-) A-I      intronic
chr12:108939594(-) A-I      intronic
chr12:108940606(-) A-I      intronic
chr12:108940607(-) A-I      intronic
chr12:108940763(-) A-I      intronic
chr12:108940650(-) A-I      intronic
chr12:108939706(-) A-I      intronic
chr12:108926684(-) A-I      intronic
chr12:108940572(-) A-I      intronic
chr12:108939487(-) A-I      intronic
chr12:108939730(-) A-I      intronic
chr12:108940104(-) A-I      intronic
chr12:108926703(-) A-I      intronic
chr12:108922655(-) A-I      intronic
chr12:108922197(-) A-I      intronic
chr12:108949249(-) A-I      intronic
chr12:108922788(-) A-I      intronic
chr12:108928369(-) A-I      intronic
chr12:108928356(-) A-I      intronic
chr12:108938614(-) A-I      intronic
chr12:108950077(-) A-I      intronic
chr12:108922016(-) A-I      intronic
chr12:108926644(-) A-I      intronic
chr12:108939500(-) A-I      intronic
chr12:108935823(-) A-I      intronic
chr12:108926699(-) A-I      intronic
chr12:108940463(-) A-I      intronic
chr12:108950147(-) A-I      intronic
chr12:108928437(-) A-I      intronic
chr12:108951760(-) A-I      intronic
chr12:108939839(-) A-I      intronic
chr12:108940668(-) A-I      intronic
chr12:108935898(-) A-I      intronic
chr12:108940140(-) A-I      intronic
chr12:108926700(-) A-I      intronic
chr12:108935896(-) A-I      intronic
chr12:108925658(-) A-I      intronic
chr12:108940108(-) A-I      intronic
chr12:108949223(-) A-I      intronic
chr12:108949329(-) A-I      intronic
chr12:108926597(-) A-I      intronic
chr12:108949317(-) A-I      intronic
chr12:108939659(-) A-I      intronic
chr12:108926694(-) A-I      intronic
chr12:108921640(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED SART3
chr12:108922197(-) A-G intron -    22484847
chr12:108922655(-) A-G intron -    22484847
chr12:108922681(-) A-G intron -    22484847
chr12:108922788(-) A-G intron -    22484847
chr12:108926644(-) A-G intron -    22484847
chr12:108926684(-) A-G intron -    22484847
chr12:108928356(-) A-G intron -    22484847
chr12:108928369(-) A-G intron -    22484847
chr12:108935083(-) A-G intron -    22484847
chr12:108935586(-) A-G intron -    22484847
chr12:108939487(-) A-G intron -    22484847
chr12:108939706(-) A-G intron -    22484847
chr12:108939730(-) A-G intron -    22484847
chr12:108940104(-) A-G intron -    22484847
chr12:108940140(-) A-G intron -    22484847
chr12:108949223(-) A-G intron -    22484847
chr12:108949249(-) A-G intron -    22484847
chr12:108949317(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase SART3
chr12:108916925-108916926(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27371828//22575960
chr12:108916941-108916942(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr12:108916966-108916967(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr12:108917098-108917099(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr12:108917150-108917151(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr12:108917183-108917184(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr12:108917217-108917218(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr12:108918062-108918063(-) m6A 3'UTR//intron       24284625//27773535
chr12:108918072-108918073(-) m6A 3'UTR//intron       24284625//27773535
chr12:108918102-108918103(-) m6A 3'UTR//CDS       24284625//27773535
chr12:108918141-108918142(-) m6A 3'UTR//CDS       24284625//27773535
chr12:108918200-108918201(-) m6A 3'UTR//CDS       24284625//27773535
chr12:108919239-108919240(-) m6A 3'UTR//CDS       24284625//27773535
chr12:108919270-108919271(-) m6A 3'UTR//CDS       24284625
chr12:108920089-108920090(-) m6A 3'UTR//CDS       27773536
chr12:108920140-108920141(-) m6A 3'UTR//CDS       27371828//27773536
chr12:108920173-108920174(-) m6A 3'UTR//CDS       24209618//27773535//27371828
chr12:108920276-108920277(-) m6A 3'UTR//CDS       24209618//24981863//28052920//27773535//27371828//22575960//22608085
chr12:108920299-108920300(-) m6A 3'UTR//CDS       24209618//24981863//28052920//27773535//27371828//22608085
chr12:108923920-108923921(-) m1A 3'UTR//CDS       26863196
chr12:108923987-108923988(-) Am 3'UTR//CDS//exon       -
chr12:108924036-108924037(-) m6A 3'UTR//CDS//exon       24209618//24981863//28052920//27773535//27371828//22608085
chr12:108924049-108924050(-) m1A 3'UTR//CDS//exon       26863196
chr12:108925015-108925016(-) m6A 3'UTR//CDS//exon       24209618//24981863//27773535//22608085
chr12:108925021-108925022(-) m6A 3'UTR//CDS//exon       24981863//27773535
chr12:108925199-108925200(-) m6A exon//intron       27773535
chr12:108925215-108925216(-) m6A exon//intron       27773535
chr12:108926003-108926004(-) m6A 3'UTR//CDS//exon       27773535
chr12:108930495-108930496(-) Gm 3'UTR//CDS//exon       -
chr12:108930896-108930897(-) m6A exon//intron       -
chr12:108930907-108930908(-) m6A exon//intron       -
chr12:108936821-108936822(-) m6A CDS       27773535
chr12:108936858-108936859(-) m6A CDS       27773535
chr12:108936885-108936886(-) m6A CDS       27773535
chr12:108938272-108938273(-) m6A CDS//exon//intron       27773535
chr12:108941712-108941713(-) m6A CDS//exon       27371828//22575960
chr12:108942942-108942943(-) m6A 5'UTR//CDS//exon       24284625//25456834//27773535//27371828
chr12:108942952-108942953(-) m6A 5'UTR//CDS//exon       24284625//25456834//24981863//27773535//27371828
chr12:108947965-108947966(-) m6A 5'UTR//intron       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chr12:108954285-108954286(-) m6A 3'UTR//intron       27773535
chr12:108954366-108954367(-) m6A 3'UTR//intron       27773535
chr12:108954630-108954631(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chr12:108954649-108954650(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22608085
chr12:108954782-108954783(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr12:108954830-108954831(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr12:108954897-108954898(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr12:108954911-108954912(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr12:108954954-108954955(-) m6A 5'UTR       24284625//24209618//25456834//24981863//27773535//27371828//27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-320b
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Cytoplasm Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059
Exosome Pooled sera     27278097
Exosome Breast cancer cell line (MCF-7)     20976003
Exosome Ovarian follicular fluid     22116803
Exosome Plasma     23663360
Exosome Colon cancer cell line (LIM1863)     25330373
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Plasma     23077538
Microvesicle Seminal plasma     23539611
Microvesicle Hepatoma cells     23771658
Microvesicle Serum     24797360
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine     -
Mitochondrion Skeletal muscle myoblasts     21637849
Mitochondrion Cell line (HEK-293|HeLa)     22984580
Nucleus Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059
Nucleus Nasopharyngeal carcinoma cells     20498841
SART3
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol HCC cell line (HepG2)|K562 cells     -
Exosome Blood     -
Membrane HCC cell line (HepG2)     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus Colon cancer cells     24393600
Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -
Ribosome HEK-293 cells     22199352

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-320b
Eloxatine 5310940 Drug interaction    RC00007663
cis-Diaminedichloroplatinum 2767 Drug interaction    RC00007662
Benzene 241 Drug interaction    RC00007661
Marine fungal metabolite 1386A - Drug interaction    RC00007664
Resource Symbol Drug Name PubChem ID
RNAactDrug hsa-miR-320b
Topotecan       60700

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-320b
Interactor2: SART3

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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