Detail Information

Basic Information:


  VIRBase ID:  

HHID00068758

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-320b:           TXNL1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-320b TXNL1
miRBase
Accession/Entrez ID		 MIMAT0005792 9352
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - HEL-S-114//TRP32//Txl//TXL-1//TXNL

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-320b
rs1156276707 chr1:116671796    G/T
rs1311857670 chr1:116671805    GCAAA/G
rs1373244526 chr1:116671806    C/T
rs1434535374 chr1:116671803    G/C
rs755613466 chr1:116671797    T/C
rs779451916 chr1:116671801    G/C
rs1303311077 chr1:224257059    A/T
rs1313950455 chr1:224257062    C/A
rs1333032274 chr1:224257051    G/T
rs1445839645 chr1:224257055    T/C
rs1465806287 chr1:224257050    TGCCC/T
rs745315768 chr1:224257052    C/T
rs769446888 chr1:224257054    C/T
rs1189118293 chr1:116671788    A/G
rs1199375375 chr1:116671794    G/A
rs1411861918 chr1:116671791    G/T
rs1469116635 chr1:116671792    C/CTGGGTTGAGAGGGCAAACAAATTAACTAAT
rs1030808536 chr1:224257064    A/T
rs774951709 chr1:224257069    T/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR TXNL1
chr18:54280874(-) A-I      intronic
chr18:54280873(-) A-I      intronic
chr18:54278670(-) A-I      intronic
chr18:54278624(-) A-I      intronic
chr18:54274630(-) A-I      intronic
chr18:54274304(-) A-I      intronic
chr18:54274268(-) A-I      intronic
chr18:54266937(-) A-I      3'UTR
chr18:54266949(-) A-I      3'UTR
chr18:54266958(-) A-I      3'UTR
chr18:54266963(-) A-I      3'UTR
chr18:54266966(-) A-I      3'UTR
chr18:54266967(-) A-I      3'UTR
chr18:54266968(-) A-I      3'UTR
chr18:54266969(-) A-I      3'UTR
chr18:54266983(-) A-I      3'UTR
chr18:54266991(-) A-I      3'UTR
chr18:54266993(-) A-I      3'UTR
chr18:54288643(-) A-I      intronic
chr18:54288641(-) A-I      intronic
chr18:54288638(-) A-I      intronic
chr18:54288628(-) A-I      intronic
chr18:54288605(-) A-I      intronic
chr18:54288604(-) A-I      intronic
chr18:54288603(-) A-I      intronic
chr18:54288580(-) A-I      intronic
chr18:54280933(-) A-I      intronic
chr18:54280910(-) A-I      intronic
chr18:54290547(-) A-I      intronic
chr18:54288662(-) A-I      intronic
chr18:54288596(-) A-I      intronic
chr18:54288595(-) A-I      intronic
chr18:54288558(-) A-I      intronic
chr18:54288505(-) A-I      intronic
chr18:54287378(-) A-I      intronic
chr18:54287377(-) A-I      intronic
chr18:54287337(-) A-I      intronic
chr18:54287319(-) A-I      intronic
chr18:54287314(-) A-I      intronic
chr18:54287302(-) A-I      intronic
chr18:54286565(-) A-I      intronic
chr18:54286552(-) A-I      intronic
chr18:54286275(-) A-I      intronic
chr18:54283316(-) A-I      intronic
chr18:54283311(-) A-I      intronic
chr18:54283144(-) A-I      intronic
chr18:54283135(-) A-I      intronic
chr18:54281230(-) A-I      intronic
chr18:54281224(-) A-I      intronic
chr18:54281182(-) A-I      intronic
chr18:54281016(-) A-I      intronic
chr18:54281004(-) A-I      intronic
chr18:54280119(-) A-I      intronic
chr18:54279348(-) A-I      intronic
chr18:54279322(-) A-I      intronic
chr18:54279176(-) A-I      intronic
chr18:54279115(-) A-I      intronic
chr18:54279110(-) A-I      intronic
chr18:54279084(-) A-I      intronic
chr18:54278686(-) A-I      intronic
chr18:54278664(-) A-I      intronic
chr18:54278514(-) A-I      intronic
chr18:54278496(-) A-I      intronic
chr18:54278486(-) A-I      intronic
chr18:54278456(-) A-I      intronic
chr18:54273486(-) A-I      intronic
chr18:54273426(-) A-I      intronic
chr18:54293978(-) A-I      intronic
chr18:54293974(-) A-I      intronic
chr18:54290607(-) A-I      intronic
chr18:54293979(-) A-I      intronic
chr18:54298214(-) A-I      intronic
chr18:54275074(-) A-I      intronic
chr18:54275040(-) A-I      intronic
chr18:54298244(-) A-I      intronic
chr18:54299067(-) A-I      intronic
chr18:54302367(-) A-I      intronic
chr18:54302376(-) A-I      intronic
chr18:54302380(-) A-I      intronic
chr18:54302483(-) A-I      intronic
chr18:54302489(-) A-I      intronic
chr18:54281142(-) A-I      intronic
chr18:54273561(-) A-I      intronic
chr18:54275030(-) A-I      intronic
chr18:54290576(-) A-I      intronic
chr18:54274243(-) A-I      intronic
chr18:54274979(-) A-I      intronic
chr18:54274975(-) A-I      intronic
chr18:54274947(-) A-I      intronic
chr18:54274924(-) A-I      intronic
chr18:54274601(-) A-I      intronic
chr18:54274512(-) A-I      intronic
chr18:54274305(-) A-I      intronic
chr18:54274278(-) A-I      intronic
chr18:54290572(-) A-I      intronic
chr18:54274660(-) A-I      intronic
chr18:54279813(-) A-I      intronic
chr18:54274289(-) A-I      intronic
chr18:54294068(-) A-I      intronic
chr18:54288594(-) A-I      intronic
chr18:54275004(-) A-I      intronic
chr18:54280788(-) A-I      intronic
chr18:54280936(-) A-I      intronic
chr18:54274378(-) A-I      intronic
chr18:54279330(-) A-I      intronic
chr18:54274251(-) A-I      intronic
chr18:54273350(-) A-I      intronic
chr18:54279030(-) A-I      intronic
chr18:54299069(-) A-I      intronic
chr18:54280234(-) A-I      intronic
chr18:54273496(-) A-I      intronic
chr18:54274359(-) A-I      intronic
chr18:54278617(-) A-I      intronic
chr18:54274836(-) A-I      intronic
chr18:54279244(-) A-I      intronic
chr18:54298310(-) A-I      intronic
chr18:54278651(-) A-I      intronic
chr18:54279053(-) A-I      intronic
chr18:54279371(-) A-I      intronic
chr18:54288602(-) A-I      intronic
chr18:54279191(-) A-I      intronic
chr18:54297302(-) A-I      intronic
chr18:54274593(-) A-I      intronic
chr18:54288657(-) A-I      intronic
chr18:54274328(-) A-I      intronic
chr18:54288540(-) A-I      intronic
chr18:54301087(-) A-I      intronic
chr18:54300815(-) A-I      intronic
chr18:54298164(-) A-I      intronic
chr18:54288586(-) A-I      intronic
chr18:54274978(-) A-I      intronic
chr18:54288504(-) A-I      intronic
chr18:54286524(-) A-I      intronic
chr18:54298209(-) A-I      intronic
chr18:54287382(-) A-I      intronic
chr18:54302318(-) A-I      intronic
chr18:54274845(-) A-I      intronic
chr18:54274444(-) A-I      intronic
chr18:54274682(-) A-I      intronic
chr18:54280840(-) A-I      intronic
chr18:54294174(-) A-I      intronic
chr18:54281177(-) A-I      intronic
chr18:54297281(-) A-I      intronic
chr18:54280210(-) A-I      intronic
chr18:54280926(-) A-I      intronic
chr18:54280828(-) A-I      intronic
chr18:54280343(-) A-I      intronic
chr18:54279370(-) A-I      intronic
chr18:54298390(-) A-I      intronic
chr18:54274499(-) A-I      intronic
chr18:54280200(-) A-I      intronic
chr18:54278611(-) A-I      intronic
chr18:54297364(-) A-I      intronic
chr18:54278676(-) A-I      intronic
chr18:54274971(-) A-I      intronic
chr18:54273443(-) A-I      intronic
chr18:54279088(-) A-I      intronic
chr18:54274588(-) A-I      intronic
chr18:54274633(-) A-I      intronic
chr18:54281040(-) A-I      intronic
chr18:54279204(-) A-I      intronic
chr18:54281181(-) A-I      intronic
chr18:54280322(-) A-I      intronic
chr18:54278689(-) A-I      intronic
chr18:54280827(-) A-I      intronic
chr18:54302325(-) A-I      intronic
chr18:54280985(-) A-I      intronic
chr18:54294243(-) A-I      intronic
chr18:54274445(-) A-I      intronic
chr18:54274429(-) A-I      intronic
chr18:54278585(-) A-I      intronic
chr18:54274638(-) A-I      intronic
chr18:54274250(-) A-I      intronic
chr18:54278565(-) A-I      intronic
chr18:54279354(-) A-I      intronic
chr18:54278501(-) A-I      intronic
chr18:54280842(-) A-I      intronic
chr18:54298402(-) A-I      intronic
chr18:54286669(-) A-I      intronic
chr18:54302402(-) A-I      intronic
chr18:54293960(-) A-I      intronic
chr18:54278584(-) A-I      intronic
chr18:54278474(-) A-I      intronic
chr18:54278681(-) A-I      intronic
chr18:54274639(-) A-I      intronic
chr18:54274987(-) A-I      intronic
chr18:54279218(-) A-I      intronic
chr18:54299068(-) A-I      intronic
chr18:54274849(-) A-I      intronic
chr18:54288652(-) A-I      intronic
chr18:54274553(-) A-I      intronic
chr18:54280917(-) A-I      intronic
chr18:54280810(-) A-I      intronic
chr18:54273348(-) A-I      intronic
chr18:54278621(-) A-I      intronic
chr18:54275084(-) A-I      intronic
chr18:54274661(-) A-I      intronic
chr18:54278650(-) A-I      intronic
chr18:54281006(-) A-I      intronic
chr18:54279878(-) A-I      intronic
chr18:54280998(-) A-I      intronic
chr18:54279074(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED TXNL1
chr18:54279330(-) A-I intron -    15342557
chr18:54279344(-) A-I intron -    15342557
chr18:54279354(-) A-I intron -    15342557
chr18:54279371(-) A-I intron -    15342557
chr18:54279377(-) A-I intron -    15342557
chr18:54279813(-) A-I intron -    15342557
chr18:54281181(-) A-I intron -    15342557
chr18:54278650(-) A-I intron -    22327324
chr18:54278651(-) A-I intron -    22327324
chr18:54278681(-) A-I intron -    22327324
chr18:54273838(-) A-I intron -    21960545
chr18:54273947(-) A-I intron -    21960545
chr18:54274250(-) A-G intron -    22484847
chr18:54274283(-) A-G intron -    22484847
chr18:54274445(-) A-G intron -    22484847
chr18:54274448(-) A-G intron -    22484847
chr18:54274491(-) A-G intron -    22484847
chr18:54274522(-) A-G intron -    22484847
chr18:54274588(-) A-G intron -    22484847
chr18:54274638(-) A-G intron -    22484847
chr18:54274978(-) A-G intron -    22484847
chr18:54275004(-) A-G intron -    22484847
chr18:54278474(-) A-G intron -    22484847
chr18:54278650(-) A-G intron -    22484847
chr18:54278651(-) A-G intron -    22484847
chr18:54279878(-) A-G intron -    22484847
chr18:54280343(-) A-G intron -    22484847
chr18:54280828(-) A-G intron -    22484847
chr18:54299068(-) A-G intron -    22484847
chr18:54299069(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase TXNL1
chr18:54264518-54264519(-) m6A 3'UTR       27773535
chr18:54264545-54264546(-) m6A 3'UTR       27773535
chr18:54264590-54264591(-) m6A 3'UTR       27773535
chr18:54264627-54264628(-) m6A 3'UTR       27773535
chr18:54264675-54264676(-) m6A 3'UTR       27773535
chr18:54264791-54264792(-) m6A 3'UTR       27773535
chr18:54264809-54264810(-) m6A 3'UTR       27773535
chr18:54264830-54264831(-) m6A 3'UTR       27773535
chr18:54264887-54264888(-) m6A 3'UTR       27773535
chr18:54264940-54264941(-) m6A 3'UTR       27773535
chr18:54264965-54264966(-) m6A 3'UTR       27773535
chr18:54265287-54265288(-) m6A 3'UTR       27773535
chr18:54267637-54267638(-) m6A 3'UTR//exon//intron       27773535
chr18:54267773-54267774(-) m6A 3'UTR//exon//intron       27773535
chr18:54269549-54269550(-) m6A 3'UTR       27773535
chr18:54269587-54269588(-) m6A 3'UTR       27773535
chr18:54269657-54269658(-) m6A 3'UTR       27773535
chr18:54291540-54291541(-) m6A 3'UTR//CDS       24981863
chr18:54291636-54291637(-) m6A 3'UTR//CDS       27773535
chr18:54291688-54291689(-) m6A 3'UTR//CDS       27773535
chr18:54305802-54305803(-) m6A 5'UTR//intron       25456834//24981863//27773535//27371828
chr18:54318525-54318526(-) m6A 5'UTR       -

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-320b
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Cytoplasm Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059
Exosome Pooled sera     27278097
Exosome Breast cancer cell line (MCF-7)     20976003
Exosome Ovarian follicular fluid     22116803
Exosome Plasma     23663360
Exosome Colon cancer cell line (LIM1863)     25330373
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Plasma     23077538
Microvesicle Seminal plasma     23539611
Microvesicle Hepatoma cells     23771658
Microvesicle Serum     24797360
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine     -
Mitochondrion Skeletal muscle myoblasts     21637849
Mitochondrion Cell line (HEK-293|HeLa)     22984580
Nucleus Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059
Nucleus Nasopharyngeal carcinoma cells     20498841
TXNL1
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleoplasm K562 cells     -
Nucleus K562 cells     -
Ribosome HEK-293 cells     22199352
Ribosome Colon cancer cells     24393600

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-320b
Eloxatine 5310940 Drug interaction    RC00007663
cis-Diaminedichloroplatinum 2767 Drug interaction    RC00007662
Benzene 241 Drug interaction    RC00007661
Marine fungal metabolite 1386A - Drug interaction    RC00007664
Resource Symbol Drug Name PubChem ID
RNAactDrug hsa-miR-320b
Topotecan       60700

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-320b
Interactor2: TXNL1

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region CDS
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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