Basic Information:

  VIRBase ID:  

HHID00068654

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-1224-5p:  MIMAT0005458          ZC3H12C:  NM_033390     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-1224-5p	ZC3H12C
miRBase Accession/Entrez ID	MIMAT0005458	85463
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	MCPIP3

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-1224-5p	rs1049510662 chr3:184241414    C/T rs1390231699 chr3:184241420    G/A rs753013509 chr3:184241417    G/A rs755127631 chr3:184241415    G/A rs755127631 chr3:184241415    G/T rs919353291 chr3:184241422    G/T rs1367940309 chr3:184241410    G/A rs1367940309 chr3:184241410    G/C rs777592974 chr3:184241406    TGAGGACTCGG/T

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	ZC3H12C	chr11:110032818(+) A-I      intronic chr11:110037435(+) A-I      3'UTR chr11:110041539(+) A-I      3'UTR chr11:110032826(+) A-I      intronic chr11:110032851(+) A-I      intronic chr11:110032869(+) A-I      intronic chr11:110032755(+) A-I      intronic chr11:110024096(+) A-I      intronic chr11:110009504(+) A-I      intronic chr11:109973463(+) A-I      intronic chr11:109972377(+) A-I      intronic chr11:109972372(+) A-I      intronic chr11:109972353(+) A-I      intronic chr11:109972352(+) A-I      intronic chr11:109972342(+) A-I      intronic chr11:109972292(+) A-I      intronic chr11:110032811(+) A-I      intronic chr11:110010848(+) A-I      intronic chr11:110029070(+) A-I      intronic chr11:110027720(+) A-I      intronic chr11:110028261(+) A-I      intronic chr11:110031778(+) A-I      intronic chr11:109974814(+) A-I      intronic chr11:110027705(+) A-I      intronic chr11:110031832(+) A-I      intronic chr11:109974430(+) A-I      intronic chr11:110032738(+) A-I      intronic chr11:110008717(+) A-I      intronic chr11:110029085(+) A-I      intronic chr11:110028346(+) A-I      intronic chr11:110032813(+) A-I      intronic chr11:109970417(+) A-I      intronic chr11:110029195(+) A-I      intronic chr11:109986200(+) A-I      intronic chr11:110028290(+) A-I      intronic chr11:109986289(+) A-I      intronic chr11:110032748(+) A-I      intronic chr11:110031843(+) A-I      intronic chr11:110032722(+) A-I      intronic chr11:110032680(+) A-I      intronic chr11:110032672(+) A-I      intronic chr11:110032669(+) A-I      intronic chr11:110032657(+) A-I      intronic chr11:110031803(+) A-I      intronic chr11:110031749(+) A-I      intronic chr11:110031665(+) A-I      intronic chr11:110029083(+) A-I      intronic chr11:110029002(+) A-I      intronic chr11:110028390(+) A-I      intronic chr11:110028361(+) A-I      intronic chr11:110028265(+) A-I      intronic chr11:110028224(+) A-I      intronic chr11:110028179(+) A-I      intronic chr11:110027797(+) A-I      intronic chr11:110027793(+) A-I      intronic chr11:110027765(+) A-I      intronic chr11:110027752(+) A-I      intronic chr11:110027742(+) A-I      intronic chr11:110027739(+) A-I      intronic chr11:110010825(+) A-I      intronic chr11:110008769(+) A-I      intronic chr11:110008753(+) A-I      intronic chr11:110008745(+) A-I      intronic chr11:110008715(+) A-I      intronic chr11:109996277(+) A-I      intronic chr11:109996226(+) A-I      intronic chr11:109996163(+) A-I      intronic chr11:109996146(+) A-I      intronic chr11:109996145(+) A-I      intronic chr11:109996097(+) A-I      intronic chr11:110028260(+) A-I      intronic chr11:109989506(+) A-I      intronic chr11:109989505(+) A-I      intronic chr11:109989424(+) A-I      intronic chr11:109989423(+) A-I      intronic chr11:109989388(+) A-I      intronic chr11:109989375(+) A-I      intronic chr11:109998500(+) A-I      intronic chr11:109986737(+) A-I      intronic chr11:109986695(+) A-I      intronic chr11:109986685(+) A-I      intronic chr11:109986674(+) A-I      intronic chr11:109986670(+) A-I      intronic chr11:109986668(+) A-I      intronic chr11:109986544(+) A-I      intronic chr11:109986230(+) A-I      intronic chr11:109972516(+) A-I      intronic chr11:109972509(+) A-I      intronic chr11:109972477(+) A-I      intronic chr11:109972412(+) A-I      intronic chr11:109972402(+) A-I      intronic chr11:109972390(+) A-I      intronic chr11:109972438(+) A-I      intronic chr11:109970427(+) A-I      intronic chr11:109978161(+) A-I      intronic chr11:110028318(+) A-I      intronic chr11:109970387(+) A-I      intronic chr11:110028350(+) A-I      intronic chr11:110028239(+) A-I      intronic chr11:110028302(+) A-I      intronic chr11:110028246(+) A-I      intronic chr11:109989443(+) A-I      intronic chr11:110032601(+) A-I      intronic chr11:109970459(+) A-I      intronic chr11:110009363(+) A-I      intronic chr11:109986237(+) A-I      intronic chr11:110032600(+) A-I      intronic chr11:109996127(+) A-I      intronic chr11:110024998(+) A-I      intronic chr11:109996278(+) A-I      intronic chr11:110031691(+) A-I      intronic chr11:109998455(+) A-I      intronic chr11:110028286(+) A-I      intronic chr11:109996223(+) A-I      intronic chr11:109986128(+) A-I      intronic chr11:109986131(+) A-I      intronic chr11:109986194(+) A-I      intronic chr11:110027728(+) A-I      intronic chr11:110027694(+) A-I      intronic chr11:109972373(+) A-I      intronic chr11:110028353(+) A-I      intronic chr11:109978721(+) A-I      intronic chr11:110028375(+) A-I      intronic chr11:110009493(+) A-I      intronic chr11:110006050(+) A-I      intronic chr11:110031804(+) A-I      intronic chr11:109989260(+) A-I      intronic chr11:109982947(+) A-I      intronic chr11:109986619(+) A-I      intronic chr11:110010811(+) A-I      intronic chr11:109974946(+) A-I      intronic chr11:110031701(+) A-I      intronic chr11:110028344(+) A-I      intronic chr11:110031631(+) A-I      intronic chr11:109970384(+) A-I      intronic chr11:110025893(+) A-I      intronic chr11:109972414(+) A-I      intronic chr11:109972489(+) A-I      intronic chr11:109989307(+) A-I      intronic chr11:110028330(+) A-I      intronic chr11:110010851(+) A-I      intronic chr11:109998405(+) A-I      intronic chr11:110028264(+) A-I      intronic chr11:109970480(+) A-I      intronic chr11:110031662(+) A-I      intronic chr11:110009506(+) A-I      intronic chr11:109974395(+) A-I      intronic chr11:110028234(+) A-I      intronic chr11:109978773(+) A-I      intronic chr11:110028345(+) A-I      intronic chr11:110010856(+) A-I      intronic chr11:110005937(+) A-I      intronic chr11:109986145(+) A-I      intronic chr11:110028335(+) A-I      intronic chr11:110027651(+) A-I      intronic chr11:109996217(+) A-I      intronic chr11:110031766(+) A-I      intronic chr11:110028370(+) A-I      intronic chr11:109974354(+) A-I      intronic chr11:110009505(+) A-I      intronic chr11:110029192(+) A-I      intronic chr11:110032670(+) A-I      intronic chr11:110031752(+) A-I      intronic chr11:110028178(+) A-I      intronic chr11:109970463(+) A-I      intronic chr11:110006170(+) A-I      intronic chr11:110028278(+) A-I      intronic chr11:110028300(+) A-I      intronic chr11:110025953(+) A-I      intronic chr11:110031831(+) A-I      intronic chr11:110028399(+) A-I      intronic chr11:110023936(+) A-I      intronic chr11:110031626(+) A-I      intronic chr11:109976739(+) A-I      intronic chr11:109970385(+) A-I      intronic chr11:110008730(+) A-I      intronic chr11:110029150(+) A-I      intronic chr11:109996317(+) A-I      intronic chr11:110032712(+) A-I      intronic chr11:109986603(+) A-I      intronic chr11:109986107(+) A-I      intronic chr11:109986290(+) A-I      intronic chr11:110027757(+) A-I      intronic chr11:110032739(+) A-I      intronic chr11:110027733(+) A-I      intronic chr11:109998364(+) A-I      intronic chr11:110032850(+) A-I      intronic chr11:110031606(+) A-I      intronic chr11:110028400(+) A-I      intronic chr11:110031698(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	ZC3H12C	chr11:110028345(+) A-I intron -    22327324 chr11:109986128(+) A-G intron -    22484847 chr11:109986131(+) A-G intron -    22484847 chr11:109986145(+) A-G intron -    22484847 chr11:109986290(+) A-G intron -    22484847 chr11:110010811(+) A-G intron -    22484847 chr11:110027733(+) A-G intron -    22484847 chr11:110028261(+) A-G intron -    22484847 chr11:110028345(+) A-G intron -    22484847 chr11:110028346(+) A-G intron -    22484847 chr11:110029195(+) A-G intron -    22484847 chr11:110031606(+) A-G intron -    22484847 chr11:110032748(+) A-G intron -    22484847 chr11:110032813(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	ZC3H12C	chr11:110007559-110007560(+) m6A CDS       22608085 chr11:110007643-110007644(+) m6A CDS       24284625//24209618//24981863//22608085 chr11:110007668-110007669(+) m6A CDS       24284625//24209618//24981863//22575960//22608085 chr11:110007711-110007712(+) m6A CDS       24284625//24209618//24981863//22575960//22608085 chr11:110007719-110007720(+) m6A CDS       24284625//24209618//24981863//22575960//22608085 chr11:110007781-110007782(+) m6A CDS       24284625//24981863//22575960//22608085 chr11:110007788-110007789(+) m6A CDS       24284625//24981863//22575960//22608085 chr11:110007804-110007805(+) m6A CDS       24284625//24981863//22575960//22608085 chr11:110007827-110007828(+) m6A CDS       24284625//24981863//22575960//22608085 chr11:110007855-110007856(+) m6A CDS       24284625//24981863//22575960//22608085 chr11:110007860-110007861(+) m6A CDS       24284625//24981863//22575960//22608085 chr11:110007896-110007897(+) m6A CDS       24284625//24981863//22575960//22608085 chr11:110007916-110007917(+) m6A CDS       24284625//24981863//22575960//22608085 chr11:110007959-110007960(+) m6A CDS       24284625//24981863//22575960//22608085 chr11:110007968-110007969(+) m6A CDS       24284625//24981863//22608085 chr11:110008029-110008030(+) m6A CDS       24209618//24981863//22608085 chr11:110008103-110008104(+) m6A CDS       24209618//24981863//22608085 chr11:110023651-110023652(+) m6A CDS       24209618 chr11:110035084-110035085(+) m6A CDS       24981863 chr11:110035147-110035148(+) m6A CDS       24284625//24981863//22608085 chr11:110035181-110035182(+) m6A CDS       24284625//24981863//22608085 chr11:110035198-110035199(+) m6A CDS       24284625//24981863//22608085 chr11:110035298-110035299(+) m6A CDS       24284625//24981863//22608085 chr11:110035314-110035315(+) m6A CDS       24284625//24981863//22608085 chr11:110035341-110035342(+) m6A CDS       24284625//24981863//22608085 chr11:110035352-110035353(+) m6A CDS       24284625//24981863//22608085 chr11:110035402-110035403(+) m6A CDS       24284625//24981863//22608085 chr11:110035471-110035472(+) m6A CDS       24284625//24981863//22608085 chr11:110035480-110035481(+) m6A CDS       24284625//24981863//22608085 chr11:110035537-110035538(+) m6A CDS       24284625//24981863//22608085 chr11:110035650-110035651(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr11:110035891-110035892(+) m6A CDS       24284625//24981863//22608085 chr11:110036055-110036056(+) m6A CDS       24284625//24209618//24981863//22575960//22608085 chr11:110036183-110036184(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr11:110036316-110036317(+) m6A CDS       24284625//24209618//24981863//22608085 chr11:110036658-110036659(+) m6A 3'UTR       24981863 chr11:110036867-110036868(+) m6A 3'UTR       24981863//22608085 chr11:110036879-110036880(+) m6A 3'UTR       24981863//22608085 chr11:110036888-110036889(+) m6A 3'UTR       24981863//22608085 chr11:110036916-110036917(+) m6A 3'UTR       24981863//22608085 chr11:110040485-110040486(+) m6A 3'UTR       22608085 chr11:110042092-110042093(+) m6A 3'UTR       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-1224-5p	Exosome Jurkat-derived T cell line (J77cl20)     21505438 Exosome Plasma     23663360 Exosome Blood     - Microvesicle Seminal plasma     23539611 Microvesicle Cerebrospinal fluid     24797360 Microvesicle Blood|Fibroblasts     - Mitochondrion Cell line (HEK-293)     22984580
	ZC3H12C	Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Membrane K562 cells     - Nucleoplasm K562 cells     - Nucleus K562 cells     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID	Function
ncDR	hsa-miR-1224-5p	Iodine Green 9956454 Drug sensitive 2-(2,4-Difluorophenyl)-4,5,6,7-tetrafluoro-1H-isoindole-1,3(2H)-dione 9905583 Drug sensitive 5-Iodo-8-quinolinol 96111 Drug sensitive Triapine 9571836 Drug sensitive 1-(4-Methoxyphenyl)-3-[(2-oxo-3-indolyl)amino]thiourea 947057 Drug sensitive (3Z,8S,11Z,16S)-8,16-Bis(2-oxopropyl)-1,9-dioxacyclohexadeca-3,11-diene-2,5,10,13-tetrone 92973777 Drug sensitive Cyclo[N-methyl-L-alanyl-beta-alanyl-(2R)-2-hydroxy-4-pentenoyl-L-prolyl-L-isoleucyl-N-methyl-L-valyl] 91746256 Drug sensitive [(1R,2Z,4R,8R,9R,11R,12S)-1,12-Dihydroxy-2-(hydroxymethyl)-11-methyl-7-methylidene-6-oxo-5,14-dioxatricyclo[9.2.1.04,8]tetradec-2-en-9-yl] (Z)-2-methylbut-2-enoate 90475906 Drug sensitive [(1R,2S,6R,7R,9S,12S,13S)-13-(Acetyloxymethyl)-12-hydroxy-9-methyl-5-methylidene-4-oxo-3,14-dioxatricyclo[7.4.1.02,6]tetradecan-7-yl] (Z)-2-(acetyloxymethyl)but-2-enoate 90473692 Drug sensitive 2,5-Dimethyl-1,4-benzoquinone 8718 Drug sensitive Acid Green 27 80837 Drug sensitive Jacaranone 73307 Drug sensitive 4,7-Diphenyl-1,10-phenanthroline 72812 Drug sensitive Redoxal 72571 Drug sensitive Piperidinium pentamethylenedithiocarbamate 72508 Drug sensitive 10,11-Methylenedioxy-20S-camptothecin 72403 Drug sensitive 7-Hydroxystaurosporine 72271 Drug sensitive Daniquidone 71750 Drug sensitive 2-Butenoic acid, 2-methyl-, 2,3,3a,4,5,8,9,11a-octahydro-8-hydroxy-6-(hydroxymethyl)-10-methyl-3-methylene-2-oxocyclodeca(b)furan-4-yl ester, (3aR-(3aR*,4R*(Z),6Z,8S*,10E,11aR*))- 71586750 Drug sensitive Lauryl isoquinolinium bromide 7132 Drug sensitive NO Data IN this field 6711510 Drug sensitive Antineoplastic-301477 6711219 Drug sensitive (2R,3R,4S,5R)-2-(6-Benzylsulfanylpurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol 6477178 Drug sensitive Vicenistatin 6438888 Drug sensitive Verrucarin A 6326658 Drug sensitive Chalcone analog 6296717 Drug sensitive Irinotecan 60838 Drug sensitive Topotecan 60700 Drug sensitive Triethylenemelamine 5799 Drug sensitive 6-[2-[(2-Methylsulfonylethylamino)methyl]-1,3-thiazol-4-yl]-N-[4-[[3-(trifluoromethyl)phenyl]methoxy]phenyl]quinazolin-4-amine;hydrochloride 57395317 Drug resistant Teclothiazide potassium 56841138 Drug sensitive Liatris laevigata lactone #2 5477810 Drug sensitive 7Z-Plakortide H 5472712 Drug sensitive 3-Deazauridine 54684286 Drug sensitive (Z)-4-Bromo-4-iodo-3-phenylbut-3-en-2-one 5467656 Drug sensitive 3,19-(4-Acetamido)benzylidineandrographolide 54612901 Drug sensitive 9-alpha-Acetoxyparthenolide 54611286 Drug sensitive p-Chloranilinum[bis(p-chloraniline)dioxalatoruthenate(III)] 54608061 Drug sensitive Betuletol 5459196 Drug sensitive Cuspidatin C 5459164 Drug sensitive Trunculin A 5459125 Drug sensitive (E)-1-(2,5-Dihydroxyphenyl)ethene-2-isonitrile 5388136 Drug sensitive Heliangolide 5384466 Drug sensitive Acetylrolandrolide 5384465 Drug sensitive (1E,4E)-1,5-Dipyridin-3-ylpenta-1,4-dien-3-one 5382674 Drug sensitive Crassin, acetate 5355441 Drug sensitive MX2 hydrochloride 5351347 Drug sensitive 4-(N-(4-Cyclohexylbenzyl)-2-(2,3,4,5,6-pentafluoro-N-methylphenylsulfonamido)acetamido)-2-hydroxybenzoic acid 53388144 Drug sensitive Chaetochromin 53277 Drug sensitive Improsulfan hydrochloride 5284401 Drug sensitive Guanosine,3',5'-tripropanoate 5035970 Drug sensitive Kekule 499328 Drug sensitive Pyrimethamine 4993 Drug sensitive Elsinochrome C 495866 Drug sensitive Dioxadet 48858 Drug sensitive 1,4-Phenanthrenedione, 10-(formyloxy)-4b,5,6,7,8,8a,9,10-octahydro-3,9-dihydroxy-4b,8,8-trimethyl-2-(1-methylethyl)-, (4bS,8aS,9S,10S)- 462176 Drug sensitive Melphalan 460612 Drug sensitive Aphidicolin 457964 Drug sensitive Aclarubicin 451415 Drug sensitive SMA-838 (HCl salt of NSC 188491) 45028430 Drug sensitive BAS100 Monohydrate 45028404 Drug sensitive Isopinnatal 44558939 Drug sensitive Justicidin B 442882 Drug sensitive Oxyacanthine 442333 Drug sensitive 1-Benzyl-3-hexadecyl-2-methylimidazolium chloride 44219704 Drug sensitive Methyl 4-[4-(dimethylamino)-5-[4-hydroxy-6-methyl-5-(6-methyl-5-oxooxan-2-yl)oxyoxan-2-yl]oxy-6-methyloxan-2-yl]oxy-2-ethyl-2,5,7,12-tetrahydroxy-6,11-dioxo-3,4-dihydro-1H-tetracene-1-carboxylate 438788 Drug sensitive Physalolactone 433866 Drug sensitive Di-n-octyl-secalonsaure A 430141 Drug sensitive 10-Hydroxy-5-methoxy-1-(2-methyloxiran-2-yl)-1,2-dihydrofuro[2,3-c]xanthen-6-one 429905 Drug sensitive Mitoxantrone 4212 Drug sensitive N-[p-[[(2,4-Diamino-6-quinazolinyl)methyl]amino]benzoyl]-L-aspartic acid 419263 Drug sensitive 4-(4'-Hydroxyphenyl)diazenylbenzenesulfonamide 404195 Drug sensitive Mechlorethamine 4033 Drug sensitive Loratadine 3957 Drug sensitive Lomustine 3950 Drug sensitive 2,5-Bis(aziridin-1-yl)-3-(hydroxymethyl)-6-methylcyclohexa-2,5-diene-1,4-dione 394347 Drug sensitive Sjg-136 393111 Drug sensitive Leflunomide 3899 Drug sensitive Lapachol 3884 Drug sensitive N-(2-Bromo-5-methoxybenzylidene)-6,7-dimethoxy-1-naphthalenamine 387181 Drug sensitive Pyrimidin-2-amine, 4-(2-hydroxy-4-methoxyphenyl)-6-phenyl- 386505 Drug sensitive ARQ monoacetate 385441 Drug sensitive 2,5-Bis(3-Amino-2,4,6-trinitrophenyl)-1,3,4-thiadiazole 385374 Drug sensitive Stereoisomer of NSC 674066-O 384359 Drug sensitive 4-Azido-2-chloro-3-cyanoquinoline 381915 Drug sensitive 1-Azido-2-phenyl-3-phenalenone 381891 Drug sensitive 1-(2-(Hydroxymethyl)-1,3-dioxolan-4-yl)cytosine 381525 Drug sensitive Carquniostatin B 380452 Drug sensitive 3,8-Dimethyl-1,2-naphthoquinone 373912 Drug sensitive O-Benzylfluorescein benzyl ester 371436 Drug sensitive 1,2-Dimethyl-phenothiazone 369387 Drug sensitive 7-Chloro-1-methyl-phenothiazone 369386 Drug sensitive Benzoxazole, 2-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]- 364608 Drug sensitive 4-(1-Benzofuran-2-yl)-7-methoxychromen-2-one 364364 Drug resistant 4-Nitro-6-(trifluoromethyl)-2,1,3-benzoselenadiazole 362897 Drug sensitive Aplidazole C . TFA 362402 Drug sensitive 7,12-Epidioxybenz[a]anthracene, 7,12-dihydro-7-methyl- 362095 Drug sensitive 3-Deazaneplanocin hydrochloride 358176 Drug sensitive Dolastatin 11 354399 Drug sensitive 5-(4-Azido-3-chlorophenyl)-6-ethylpyrimidine-2,4-diamine 353605 Drug sensitive Trimetrexate glucuronic acid salt 336805 Drug sensitive Predorine 333830 Drug sensitive 4-Ethyl-6-methoxy-7-(oxiran-2-ylmethoxy)quinazoline 333565 Drug sensitive Bishelenalinyl malonate 330973 Drug sensitive Dmask 32465 Drug sensitive Hydroxypristimerin 320914 Drug sensitive 5-Cinnamylidene-1,3-thiazolidine-2,4-dione 315044 Drug sensitive 2,3-Dimethoxy-5-naphthalen-2-ylsulfanylcyclohexa-2,5-diene-1,4-dione 314728 Drug sensitive Daunorubicin 30323 Drug sensitive 1,1-Dimethyl-5-(2-naphthalenyl)dithiobiuret 3004012 Drug sensitive P-Ara-C 282479 Drug sensitive Cyclo-C 279062 Drug sensitive 2-Chloro-5-[4-[2-chloro-4-(4,6-diamino-2,2-dimethyl-1,3,5-triazin-1-yl)phenyl]butyl]benzenesulfonyl fluoride;ethanesulfonic acid 278692 Drug sensitive Dichloroallyl lawsone 277767 Drug sensitive 6-Bromotoyocamycin 270861 Drug sensitive Deoxycamptothecin 266552 Drug sensitive 1-(2-Chloroethyl)-3-(2,6-dioxo-3-piperidyl)-1-nitrosourea 26328 Drug sensitive 2,4,6-Trichloro-5-heptylpyrimidine 260791 Drug sensitive Carmofur 2577 Drug sensitive 2'-Deoxy-5-(trifluoromethyl)uridine 253083 Drug sensitive 2,4,6-Trichloro-5-ethylpyrimidine 249455 Drug sensitive 9H-Purine, 6-(benzylthio)-9-(2-chloroethyl)- 246230 Drug sensitive Antimycin A3 245869 Drug sensitive Camptothecin 24360 Drug sensitive N-[(4R)-4-[(3R,5R,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-Tris(3-aminopropoxy)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentyl]octan-1-amine 24205348 Drug sensitive Mepacrine mustard dihydrochloride 24180972 Drug sensitive 9H-Purine, 2-amino-6-(o-chlorobenzylthio)-9-propyl- 239486 Drug sensitive 7-Fluoro-2-benzoyl-3-trifluoromethylquioxaline 1,4-dioxide 23635154 Drug sensitive Amsacrine 2179 Drug sensitive Diethylcarbamodithioic acid, sodium salt 21192315 Drug sensitive Cladribine 20279 Drug sensitive 4-Chloro-5-phenoxy-3H-1,2-dithiole-3-thione 16766044 Drug sensitive Azaribine 16574 Drug sensitive Arypurine derivatives 16220246 Drug sensitive GemMP[10] 16129935 Drug sensitive 1,2:5,6-Dianhydrogalactitol 15942827 Drug sensitive 2,6-Dibenzylidenecyclohexanone 1550330 Drug sensitive (2Z,9E,13Z,15E)-4',11-Dihydroxy-2,4',9-trimethylspiro[3-aza-1(2,4)-thiazolacyclohexadecaphanene-6,3'-[1,2]dithiolane]-9,13,15-triene-4,5',12-trione 2'-oxide 154730760 Drug sensitive (10S,13S,16S,19S)-16-Butan-2-yl-10,11,14-trimethyl-3-(oxiran-2-ylmethyl)-13-propan-2-yl-4-oxa-1,8,11,14,17-pentazabicyclo[17.3.0]docosane-2,5,9,12,15,18-hexone 152771884 Drug sensitive Sulfanilanilide, 4'-(9-acridinylamino)- 148802 Drug sensitive Ellipticine analog 148569 Drug sensitive 1H-2,10a-Ethanophenanthrene, kaur-16-en-15-one deriv. 146156727 Drug sensitive Edelfosine 1392 Drug sensitive Methyl (3'R)-3,4',9',10-tetrahydroxy-3'-[(2S,4R,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-7'-methoxy-5',8',9-trioxospiro[3,4-dihydropyrano[4,3-g]chromene-2,2'-3H-benzo[f][1]benzofuran]-7-carboxylate 137326876 Drug sensitive C8, Carbonyl prodigiosine 135540857 Drug sensitive Oxanthrazole 135502299 Drug sensitive 5-[(E)-[Amino(methyl)amino]azo]-1H-imidazole-4-carboxamide 135493930 Drug sensitive Cysteine, S-[(4-aminocarbonyl-1H-imidazol-5-yl)azo]- 135493928 Drug sensitive 2-Methylpropyl (3Z)-2-oxo-3-[(4-sulfamoylanilino)methylidene]-1H-indole-5-carboxylate 135421141 Drug sensitive 8-Azahypoxanthine 135410720 Drug sensitive 2-Chloro-3-(2-butoxyethoxy)naphthazarin 135406263 Drug sensitive Mercury, (4-aminophenyl)(6-thioguanosinato-N7,S6)- 135403617 Drug sensitive Raltitrexed 135400182 Drug sensitive DTIC-Dome 135398738 Drug sensitive (1R,2S,5S,8S,9S,17R,18R,21S,24R,26S,27S)-14-Chloro-5,15-dihydroxy-2,9,26-trimethyl-3,19,23,28-tetraoxaoctacyclo[16.9.1.118,27.01,5.02,24.08,17.09,14.021,26]nonacos-11-ene-4,10,22,29-tetrone 134715214 Drug sensitive [(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-Diacetyloxy-1-hydroxy-15-[(2R,3S)-2-hydroxy-3-[[(E)-2-methylbut-2-enoyl]amino]-3-phenylpropanoyl]oxy-10,14,17,17-tetramethyl-11-oxo-9-[(3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxy-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate 134714918 Drug sensitive Saintopin 131350 Drug sensitive Sendanin 12806435 Drug sensitive Terpentecin 127568 Drug sensitive Octadecylphosphocholine 125219 Drug sensitive (1S,3R,7Z,9R,12S,13R,15S)-13-Butan-2-yl-13-hydroxy-3,7,12-trimethyl-10,14,16-trioxatetracyclo[7.5.1.13,6.012,15]hexadeca-5,7-diene-4,11-dione 11972510 Drug sensitive Cytochalasin q 11970174 Drug sensitive Melampodinin 11953936 Drug sensitive Indotecan 11533060 Drug sensitive 1-Phenyl-5-(4-(trifluoromethyl)phenyl)-1H-imidazole 11162021 Drug sensitive p-Toluquinone 11122 Drug sensitive Acetylenedicarboxamide 10971 Drug sensitive 6-[4-(1-Cyclohexenyl)-1,3-butadiyn-1-yl]-2(2H)-pyranone 10263039 Drug sensitive (7S,9S)-7-[[(3As,4S,7aS)-1-[[(3aS,4S,7aS)-4-methyl-6-[[(1S,3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]-2,3a,4,6,7,7a-hexahydropyrano[4,3-d][1,3]oxazol-1-yl]methyl]-4-methyl-2,3a,4,6,7,7a-hexahydropyrano[4,3-d][1,3]oxazol-6-yl]oxy]-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione 101713728 Drug sensitive (1S,2R,4R,6S,11R,12S,15R,18S,19R,20R,21S,23R,26R)-15-Hydroxy-11,18,21-trimethyl-5,17,24,28,29-pentaoxanonacyclo[17.9.1.11,20.02,12.04,6.06,11.015,19.018,23.021,26]triacont-8-ene-10,16,25,30-tetrone 101528280 Drug sensitive Erigerol 101318126 Drug sensitive N,N-Bis(2-chloroethyl)-p-toluidine 100400 Drug sensitive Cinnoline, 4-nitro-, 1-oxide 100397 Drug sensitive Tocladesine 100299 Drug sensitive 1,3-diphenyl-4-(3-phenyl-4,5-dihydro-1H-pyrazol-5-yl)-1H-pyrazole - Drug resistant (1s,2e,4r,6r,7e,10r,11e)-2,7,11-cembratriene-4,6,10-triol - Drug sensitive 1,1'-biphenyl, 4,4'bis(thiomethyl)- - Drug sensitive 1h-1,2,4-triazole, 3-(4-diazo-4h-imidazol-5-yl)- - Drug sensitive 2,4,16-tribromoestra-1,3,5(10)-trien-3-ol-17-one - Drug sensitive 2-[(3,4-dicloro)anilino]-3-phenyl-5,7-diamino quinoxaline - Drug sensitive 3,19-benzylidine-14-deoxy-11,12-didehydroandrographolide - Drug sensitive 3,7-di(trifluoromethyl)-2-furoylquioxaline 1,4-dioxide - Drug sensitive 4'-deoxy-13',17-dinitro-3',4'-epoxy-vincaleukoblastine - Drug sensitive 4-piperidinone, 3,5-bis[(4-fluorophenyl)methylene]-, (e,e)- - Drug sensitive 7,10-acetonide of 14-hydroxy 10-deacetyl baccatin iii - Drug sensitive 7h-5,6-dithioleno[4,3-d]uracil - Drug sensitive 9,10-anthracenedione, 1-[(oxiranylmethyl)amino]- - Drug sensitive b676297k277 3',4'-deoxypsorospermin 3',4'-chlorohydrin - Drug sensitive benzene, 1,1'-[(1,3-butadiene-1,4-diyl)sulfonyl]bis - Drug sensitive benzo[1,2-c:4,5-c']dipyrrole-1,3,5,7(2h,6h)-tetraimine - Drug sensitive cis-2-hydroxymethyl-4-(isocytosin-1'-yl)-1,3-dioxolane - Drug sensitive dimethylarsinothious acid, 2,4-pyrimidinediyl ester - Drug sensitive ethanol, 2-[4-(2,2':6',2-terpyridin-4'-yl)phenoxy]- - Drug sensitive ethyl, methoxy, prodigisine - Drug sensitive ethyl-2,3-oxido-(5-bromo-2-methoxyphenyl)propionate - Drug sensitive furan-2(3h)-one, 5-(4-methylphenyl)-3,3-diphenyl- - Drug sensitive geldanamycin, n,n'-dimethyl - Drug sensitive isoflavone, 5,7-dihydroxy-4'-nitro- - Drug sensitive n,n'-bis(oxydiethylene)thiocarbamoylsulfenamide - Drug sensitive phenol, 4,4'-(5,5'-biisoxazole-3,3'-diyl)bis- - Drug sensitive propan-1-one, 2,3-dichloro-1,3-bis(4-methylphenyl)- - Drug sensitive propanedinitrile, [(3,5-dibromo-2-ethoxyphenyl)methylene]- - Drug sensitive pyrido[3',4':4,5]thieno[2,3-g]isoquinoline, 6-methyl- - Drug sensitive pyrimidine, 2,4,5-trichloro-6-propyl- - Drug sensitive salicylaldehyde, 5-bromo- (8ci) - Drug sensitive tellurium, trichloro[1,2-hexanedioato(2-)-o,o']-, ammonium - Drug sensitive tricyclo[4.4.0.0(2,7)]decane-5-one, 4,4-dibromo-2-methyl- - Drug sensitive tris(1,3-diphenylpropane-1,3-dionata)gallium(iii) - Drug sensitive (-)-dactylolide - Drug sensitive [bis(aminomethyl)diethylsilane]dichloroplatinum (ii) - Drug sensitive 2'-o-(all trans)-retinoyl-erythromicine a - Drug sensitive 7-propanoyltaxol - Drug sensitive Aminocamptothecin - Drug sensitive analog of cc-1065 - Drug sensitive Annamycin Liposomal - Drug sensitive antibiotic a54556 - Drug sensitive antineoplastic-624657 - Drug sensitive antineoplastic-d665839 - Drug sensitive Aphidicoline glycinate - Drug sensitive arylpurine derivatives - Drug sensitive Camptothecin Derivative - Drug sensitive CI-921: amsacrine derivative - Drug sensitive Copper(II) complex with quin as a ligand - Drug sensitive devadarool (erthoxydiol-x) - Drug sensitive erytroxytriol-p - Drug sensitive Indenoisoquinoline derivative - Drug sensitive insulin-methotrexate conjugate - Drug sensitive largomycin f-ii - Drug sensitive merophan - Drug sensitive mitaplatin - Drug sensitive o-linoleoyl-2-butoxy-1-desoamine - Drug sensitive organosulfur compound - Drug sensitive orlistat (usan) - Drug sensitive phosphocitrate penta sodium salt - Drug sensitive pyrazoline derivative - Drug sensitive secafascaplysin - Drug sensitive sphinxolide e - Drug sensitive thiostrepton (usan) - Drug sensitive trimethyl(phenylthio)stannane - Drug sensitive

Resource	Symbol	Drug Name	PubChem ID	Function	Link
RNAInter	hsa-miR-1224-5p	Imatinib 5291 Drug interaction    RC00007582 Doxorubicin 31703 Drug interaction    RC00007584 Hesperidin 10621 Drug interaction    RC00007583

Resource	Symbol	Drug Name	PubChem ID	PMID
NoncoRNA	hsa-miR-1224-5p	Imatinib 5291       25349971

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-1224-5p
Interactor2: ZC3H12C

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	CDS
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.