Detail Information

Basic Information:


  VIRBase ID:  

HHID00068632

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-1224-5p:           KMT2D:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-1224-5p KMT2D
miRBase
Accession/Entrez ID		 MIMAT0005458 8085
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - AAD10//ALR//CAGL114//KABUK1//KMS//MLL2//MLL4//TNRC21

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-1224-5p
rs1049510662 chr3:184241414    C/T
rs1390231699 chr3:184241420    G/A
rs753013509 chr3:184241417    G/A
rs755127631 chr3:184241415    G/A
rs755127631 chr3:184241415    G/T
rs919353291 chr3:184241422    G/T
rs1367940309 chr3:184241410    G/A
rs1367940309 chr3:184241410    G/C
rs777592974 chr3:184241406    TGAGGACTCGG/T

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase KMT2D
chr12:49412771-49412772(-) m6A 3'UTR       -
chr12:49412860-49412861(-) m6A 3'UTR       -
chr12:49413007-49413008(-) m6A 3'UTR       27773535
chr12:49413059-49413060(-) m6A 3'UTR       27773535
chr12:49413238-49413239(-) m6A 3'UTR       27773535
chr12:49413250-49413251(-) m6A 3'UTR       27773535
chr12:49413279-49413280(-) m6A 3'UTR       27773535
chr12:49413996-49413997(-) m6A 3'UTR       24981863
chr12:49414599-49414600(-) m6A 3'UTR       24981863
chr12:49414606-49414607(-) m6A 3'UTR       24981863
chr12:49414629-49414630(-) m6A 3'UTR       24981863
chr12:49414647-49414648(-) m6A 3'UTR       24981863
chr12:49414903-49414904(-) m6A 3'UTR       27773535
chr12:49415146-49415147(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr12:49415259-49415260(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr12:49415309-49415310(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr12:49415375-49415376(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27371828//27773536//22575960//22608085
chr12:49415467-49415468(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr12:49415566-49415567(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr12:49415871-49415872(-) m6A CDS       24284625//27773535//27371828
chr12:49416100-49416101(-) m6A CDS       27773535
chr12:49416107-49416108(-) m6A CDS       27773535
chr12:49416463-49416464(-) m6A CDS       27773535
chr12:49416520-49416521(-) m6A CDS       27773535
chr12:49416596-49416597(-) m6A CDS       24981863//27773535
chr12:49416643-49416644(-) m6A CDS       27773535
chr12:49418465-49418466(-) m6A CDS       27773535
chr12:49419993-49419994(-) m6A CDS       24284625
chr12:49420044-49420045(-) m6A CDS       24284625//22575960
chr12:49420102-49420103(-) Y CDS       26075521
chr12:49420181-49420182(-) m6A CDS       24284625//24209618//24981863//27773535//27371828//22575960//22608085
chr12:49420360-49420361(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr12:49420365-49420366(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr12:49420456-49420457(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr12:49420487-49420488(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr12:49420534-49420535(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr12:49420584-49420585(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr12:49420590-49420591(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr12:49420596-49420597(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr12:49420665-49420666(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr12:49420931-49420932(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22608085
chr12:49420943-49420944(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22608085
chr12:49421009-49421010(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22608085
chr12:49421588-49421589(-) m6A CDS       24284625//24209618//24981863//28052920//27773535//27371828
chr12:49421607-49421608(-) m6A CDS       24284625//24209618//24981863//28052920//27773535//27371828
chr12:49421676-49421677(-) m6A CDS       24284625//27773535//27371828
chr12:49422724-49422725(-) m6A CDS       24284625
chr12:49422893-49422894(-) m6A CDS       24284625
chr12:49423196-49423197(-) m6A CDS       24284625
chr12:49423234-49423235(-) m6A CDS       24284625
chr12:49424315-49424316(-) m6A exon//intron       27773535
chr12:49424678-49424679(-) m6A CDS//exon       24284625
chr12:49424687-49424688(-) m6A CDS//exon       24284625//27773535//27371828
chr12:49424984-49424985(-) m6A CDS//exon       24284625//24209618//25456834//27773535//27371828//27773536//22575960
chr12:49425154-49425155(-) m6A CDS//exon       24284625//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr12:49425233-49425234(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr12:49425275-49425276(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr12:49425288-49425289(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr12:49425331-49425332(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr12:49425345-49425346(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr12:49425362-49425363(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr12:49425452-49425453(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr12:49425460-49425461(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr12:49425530-49425531(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960
chr12:49425590-49425591(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr12:49425676-49425677(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr12:49425683-49425684(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr12:49425739-49425740(-) m6A CDS       24284625//25456834//24981863//27773535//27371828//22575960//22608085
chr12:49425745-49425746(-) m6A CDS       24284625//25456834//24981863//27773535//27371828//22575960//22608085
chr12:49425769-49425770(-) m6A CDS       24284625//25456834//24981863//27773535//27371828//22575960
chr12:49425864-49425865(-) m6A CDS       24284625//27773535//22575960
chr12:49425959-49425960(-) m6A CDS       24284625//22575960
chr12:49425965-49425966(-) m6A CDS       24284625//22575960
chr12:49426035-49426036(-) m6A CDS       24284625//22575960
chr12:49426190-49426191(-) m6A CDS       24284625//25456834//24981863//27773535//27371828//22575960
chr12:49426272-49426273(-) m6A CDS       24284625//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr12:49426304-49426305(-) m6A CDS       24284625//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr12:49426330-49426331(-) m6A CDS       24284625//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr12:49426398-49426399(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr12:49426407-49426408(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr12:49426412-49426413(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr12:49426540-49426541(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085
chr12:49426551-49426552(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085
chr12:49426823-49426824(-) m6A CDS       24284625//24209618//27773535
chr12:49426940-49426941(-) m6A CDS       24284625//25456834//24981863//28052920//27371828//22575960//22608085
chr12:49427012-49427013(-) m6A CDS       24284625//25456834//24981863//28052920//27371828//22575960//22608085
chr12:49427190-49427191(-) m6A CDS       27371828
chr12:49427194-49427195(-) m6A CDS       24284625//25456834//24981863//27371828//22575960//22608085
chr12:49427240-49427241(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr12:49427288-49427289(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr12:49427357-49427358(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr12:49427489-49427490(-) m6A CDS       24284625//25456834//24981863//27371828//22575960//22608085
chr12:49427697-49427698(-) m6A CDS       27773535
chr12:49427738-49427739(-) m6A CDS       27773535
chr12:49427861-49427862(-) m6A CDS       27773535
chr12:49428389-49428390(-) m6A CDS       24284625//27773535
chr12:49428409-49428410(-) m6A CDS       24284625
chr12:49431386-49431387(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr12:49431435-49431436(-) Am CDS       -
chr12:49431437-49431438(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr12:49431463-49431464(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr12:49431568-49431569(-) m6A CDS       24284625//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr12:49431667-49431668(-) m6A CDS       24284625//25456834//24981863//27371828//22575960//22608085
chr12:49431814-49431815(-) m6A CDS       24284625//25456834//24981863//27371828//22575960//22608085
chr12:49431862-49431863(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr12:49431956-49431957(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr12:49431965-49431966(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr12:49432041-49432042(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr12:49432049-49432050(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr12:49432066-49432067(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr12:49432310-49432311(-) m6A CDS//exon       24284625//25456834//24981863//27773535//27371828//22575960//22608085
chr12:49432339-49432340(-) m6A CDS//exon       24284625//25456834//24981863//27773535//27371828//22575960//22608085
chr12:49432403-49432404(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr12:49432429-49432430(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr12:49432471-49432472(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr12:49432477-49432478(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr12:49432606-49432607(-) m6A CDS//exon       24284625//25456834//24981863//27773535//27371828//22575960
chr12:49432612-49432613(-) m6A CDS//exon       24284625//25456834//24981863//27773535//22575960
chr12:49433010-49433011(-) m6A CDS//exon       24284625//27773535
chr12:49433222-49433223(-) m6A CDS       24284625
chr12:49433237-49433238(-) m6A CDS       24284625
chr12:49433330-49433331(-) m6A CDS       24284625//27371828
chr12:49433529-49433530(-) m6A CDS       24284625//27371828//22575960
chr12:49433555-49433556(-) m6A CDS       24284625//27371828//22575960
chr12:49433572-49433573(-) m6A CDS       24284625//27371828//22575960
chr12:49433604-49433605(-) m6A CDS       24284625//22575960
chr12:49433612-49433613(-) m6A CDS       24284625//22575960
chr12:49433795-49433796(-) m6A CDS       24284625//24981863//27773535
chr12:49433816-49433817(-) m6A CDS       24284625//24981863//27773535
chr12:49434452-49434453(-) m6A CDS       24284625//24981863//27773535
chr12:49434585-49434586(-) m6A CDS       24284625//24981863//27773535
chr12:49434644-49434645(-) m6A CDS       24284625//24981863//22575960
chr12:49434814-49434815(-) m6A CDS       24284625//24981863//27773535
chr12:49434847-49434848(-) m6A CDS       24284625//27773535
chr12:49435018-49435019(-) m6A CDS       24284625//25456834//22575960
chr12:49435028-49435029(-) m6A CDS       24284625//25456834//22575960
chr12:49435263-49435264(-) m6A CDS       24284625//24981863//27773535//27371828
chr12:49435290-49435291(-) m6A CDS       24284625//24981863//27773535//27371828
chr12:49435753-49435754(-) m6A CDS       27773535
chr12:49435879-49435880(-) m6A CDS       27773535
chr12:49437224-49437225(-) m6A exon//intron       27773535
chr12:49437245-49437246(-) m6A exon//intron       27773535
chr12:49437270-49437271(-) m6A exon//intron       -
chr12:49437277-49437278(-) m6A exon//intron       -
chr12:49437484-49437485(-) m6A CDS       24209618//27773535
chr12:49437536-49437537(-) m6A CDS       24209618//27773535//27371828//22575960
chr12:49437672-49437673(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960
chr12:49437680-49437681(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960
chr12:49438198-49438199(-) m6A CDS       24284625//24981863//27773535//22575960
chr12:49438227-49438228(-) m6A CDS       24284625//24981863//27773535//22575960
chr12:49438273-49438274(-) m6A CDS       24284625//27773535//22575960
chr12:49438552-49438553(-) m6A CDS       24284625//27773535//22575960
chr12:49438558-49438559(-) m6A CDS       24284625//27773535//22575960
chr12:49443467-49443468(-) m6A CDS       24284625//24209618//25456834//24981863//27371828//22575960
chr12:49443541-49443542(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr12:49443571-49443572(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr12:49443678-49443679(-) m6A CDS       24284625//24981863//27773535//27371828//22575960
chr12:49443818-49443819(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr12:49443847-49443848(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr12:49443903-49443904(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr12:49443929-49443930(-) m6A CDS       24284625//25456834//24981863//27773535//27371828//22575960//22608085
chr12:49443956-49443957(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr12:49444008-49444009(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr12:49444071-49444072(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chr12:49444109-49444110(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chr12:49444130-49444131(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828
chr12:49444147-49444148(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828
chr12:49444263-49444264(-) m6A CDS       24284625//24981863//27773535//27371828
chr12:49444432-49444433(-) m6A CDS       24284625//24981863//27773535//27371828
chr12:49444473-49444474(-) m6A CDS       24284625//24981863//27773535//27371828
chr12:49444750-49444751(-) m6A CDS       24284625//27773535
chr12:49444801-49444802(-) m6A CDS       24284625//27773535
chr12:49445037-49445038(-) m6A CDS       24284625//27773535//22575960
chr12:49445083-49445084(-) m6A CDS       24284625//24209618//27773535//22575960
chr12:49445327-49445328(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr12:49445354-49445355(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr12:49445381-49445382(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr12:49445570-49445571(-) m6A CDS       24284625//24209618//24981863//27773535//27371828//22575960
chr12:49446353-49446354(-) m6A CDS       24284625//27773535
chr12:49446380-49446381(-) m6A CDS       24284625//27773535

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-1224-5p
Exosome Jurkat-derived T cell line (J77cl20)     21505438
Exosome Plasma     23663360
Exosome Blood     -
Microvesicle Seminal plasma     23539611
Microvesicle Cerebrospinal fluid     24797360
Microvesicle Blood|Fibroblasts     -
Mitochondrion Cell line (HEK-293)     22984580
KMT2D
Chromatin HCC cell line (HepG2)|K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -
Exosome Blood     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function
ncDR hsa-miR-1224-5p
Iodine Green 9956454 Drug sensitive
2-(2,4-Difluorophenyl)-4,5,6,7-tetrafluoro-1H-isoindole-1,3(2H)-dione 9905583 Drug sensitive
5-Iodo-8-quinolinol 96111 Drug sensitive
Triapine 9571836 Drug sensitive
1-(4-Methoxyphenyl)-3-[(2-oxo-3-indolyl)amino]thiourea 947057 Drug sensitive
(3Z,8S,11Z,16S)-8,16-Bis(2-oxopropyl)-1,9-dioxacyclohexadeca-3,11-diene-2,5,10,13-tetrone 92973777 Drug sensitive
Cyclo[N-methyl-L-alanyl-beta-alanyl-(2R)-2-hydroxy-4-pentenoyl-L-prolyl-L-isoleucyl-N-methyl-L-valyl] 91746256 Drug sensitive
[(1R,2Z,4R,8R,9R,11R,12S)-1,12-Dihydroxy-2-(hydroxymethyl)-11-methyl-7-methylidene-6-oxo-5,14-dioxatricyclo[9.2.1.04,8]tetradec-2-en-9-yl] (Z)-2-methylbut-2-enoate 90475906 Drug sensitive
[(1R,2S,6R,7R,9S,12S,13S)-13-(Acetyloxymethyl)-12-hydroxy-9-methyl-5-methylidene-4-oxo-3,14-dioxatricyclo[7.4.1.02,6]tetradecan-7-yl] (Z)-2-(acetyloxymethyl)but-2-enoate 90473692 Drug sensitive
2,5-Dimethyl-1,4-benzoquinone 8718 Drug sensitive
Acid Green 27 80837 Drug sensitive
Jacaranone 73307 Drug sensitive
4,7-Diphenyl-1,10-phenanthroline 72812 Drug sensitive
Redoxal 72571 Drug sensitive
Piperidinium pentamethylenedithiocarbamate 72508 Drug sensitive
10,11-Methylenedioxy-20S-camptothecin 72403 Drug sensitive
7-Hydroxystaurosporine 72271 Drug sensitive
Daniquidone 71750 Drug sensitive
2-Butenoic acid, 2-methyl-, 2,3,3a,4,5,8,9,11a-octahydro-8-hydroxy-6-(hydroxymethyl)-10-methyl-3-methylene-2-oxocyclodeca(b)furan-4-yl ester, (3aR-(3aR*,4R*(Z),6Z,8S*,10E,11aR*))- 71586750 Drug sensitive
Lauryl isoquinolinium bromide 7132 Drug sensitive
NO Data IN this field 6711510 Drug sensitive
Antineoplastic-301477 6711219 Drug sensitive
(2R,3R,4S,5R)-2-(6-Benzylsulfanylpurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol 6477178 Drug sensitive
Vicenistatin 6438888 Drug sensitive
Verrucarin A 6326658 Drug sensitive
Chalcone analog 6296717 Drug sensitive
Irinotecan 60838 Drug sensitive
Topotecan 60700 Drug sensitive
Triethylenemelamine 5799 Drug sensitive
6-[2-[(2-Methylsulfonylethylamino)methyl]-1,3-thiazol-4-yl]-N-[4-[[3-(trifluoromethyl)phenyl]methoxy]phenyl]quinazolin-4-amine;hydrochloride 57395317 Drug resistant
Teclothiazide potassium 56841138 Drug sensitive
Liatris laevigata lactone #2 5477810 Drug sensitive
7Z-Plakortide H 5472712 Drug sensitive
3-Deazauridine 54684286 Drug sensitive
(Z)-4-Bromo-4-iodo-3-phenylbut-3-en-2-one 5467656 Drug sensitive
3,19-(4-Acetamido)benzylidineandrographolide 54612901 Drug sensitive
9-alpha-Acetoxyparthenolide 54611286 Drug sensitive
p-Chloranilinum[bis(p-chloraniline)dioxalatoruthenate(III)] 54608061 Drug sensitive
Betuletol 5459196 Drug sensitive
Cuspidatin C 5459164 Drug sensitive
Trunculin A 5459125 Drug sensitive
(E)-1-(2,5-Dihydroxyphenyl)ethene-2-isonitrile 5388136 Drug sensitive
Heliangolide 5384466 Drug sensitive
Acetylrolandrolide 5384465 Drug sensitive
(1E,4E)-1,5-Dipyridin-3-ylpenta-1,4-dien-3-one 5382674 Drug sensitive
Crassin, acetate 5355441 Drug sensitive
MX2 hydrochloride 5351347 Drug sensitive
4-(N-(4-Cyclohexylbenzyl)-2-(2,3,4,5,6-pentafluoro-N-methylphenylsulfonamido)acetamido)-2-hydroxybenzoic acid 53388144 Drug sensitive
Chaetochromin 53277 Drug sensitive
Improsulfan hydrochloride 5284401 Drug sensitive
Guanosine,3',5'-tripropanoate 5035970 Drug sensitive
Kekule 499328 Drug sensitive
Pyrimethamine 4993 Drug sensitive
Elsinochrome C 495866 Drug sensitive
Dioxadet 48858 Drug sensitive
1,4-Phenanthrenedione, 10-(formyloxy)-4b,5,6,7,8,8a,9,10-octahydro-3,9-dihydroxy-4b,8,8-trimethyl-2-(1-methylethyl)-, (4bS,8aS,9S,10S)- 462176 Drug sensitive
Melphalan 460612 Drug sensitive
Aphidicolin 457964 Drug sensitive
Aclarubicin 451415 Drug sensitive
SMA-838 (HCl salt of NSC 188491) 45028430 Drug sensitive
BAS100 Monohydrate 45028404 Drug sensitive
Isopinnatal 44558939 Drug sensitive
Justicidin B 442882 Drug sensitive
Oxyacanthine 442333 Drug sensitive
1-Benzyl-3-hexadecyl-2-methylimidazolium chloride 44219704 Drug sensitive
Methyl 4-[4-(dimethylamino)-5-[4-hydroxy-6-methyl-5-(6-methyl-5-oxooxan-2-yl)oxyoxan-2-yl]oxy-6-methyloxan-2-yl]oxy-2-ethyl-2,5,7,12-tetrahydroxy-6,11-dioxo-3,4-dihydro-1H-tetracene-1-carboxylate 438788 Drug sensitive
Physalolactone 433866 Drug sensitive
Di-n-octyl-secalonsaure A 430141 Drug sensitive
10-Hydroxy-5-methoxy-1-(2-methyloxiran-2-yl)-1,2-dihydrofuro[2,3-c]xanthen-6-one 429905 Drug sensitive
Mitoxantrone 4212 Drug sensitive
N-[p-[[(2,4-Diamino-6-quinazolinyl)methyl]amino]benzoyl]-L-aspartic acid 419263 Drug sensitive
4-(4'-Hydroxyphenyl)diazenylbenzenesulfonamide 404195 Drug sensitive
Mechlorethamine 4033 Drug sensitive
Loratadine 3957 Drug sensitive
Lomustine 3950 Drug sensitive
2,5-Bis(aziridin-1-yl)-3-(hydroxymethyl)-6-methylcyclohexa-2,5-diene-1,4-dione 394347 Drug sensitive
Sjg-136 393111 Drug sensitive
Leflunomide 3899 Drug sensitive
Lapachol 3884 Drug sensitive
N-(2-Bromo-5-methoxybenzylidene)-6,7-dimethoxy-1-naphthalenamine 387181 Drug sensitive
Pyrimidin-2-amine, 4-(2-hydroxy-4-methoxyphenyl)-6-phenyl- 386505 Drug sensitive
ARQ monoacetate 385441 Drug sensitive
2,5-Bis(3-Amino-2,4,6-trinitrophenyl)-1,3,4-thiadiazole 385374 Drug sensitive
Stereoisomer of NSC 674066-O 384359 Drug sensitive
4-Azido-2-chloro-3-cyanoquinoline 381915 Drug sensitive
1-Azido-2-phenyl-3-phenalenone 381891 Drug sensitive
1-(2-(Hydroxymethyl)-1,3-dioxolan-4-yl)cytosine 381525 Drug sensitive
Carquniostatin B 380452 Drug sensitive
3,8-Dimethyl-1,2-naphthoquinone 373912 Drug sensitive
O-Benzylfluorescein benzyl ester 371436 Drug sensitive
1,2-Dimethyl-phenothiazone 369387 Drug sensitive
7-Chloro-1-methyl-phenothiazone 369386 Drug sensitive
Benzoxazole, 2-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]- 364608 Drug sensitive
4-(1-Benzofuran-2-yl)-7-methoxychromen-2-one 364364 Drug resistant
4-Nitro-6-(trifluoromethyl)-2,1,3-benzoselenadiazole 362897 Drug sensitive
Aplidazole C . TFA 362402 Drug sensitive
7,12-Epidioxybenz[a]anthracene, 7,12-dihydro-7-methyl- 362095 Drug sensitive
3-Deazaneplanocin hydrochloride 358176 Drug sensitive
Dolastatin 11 354399 Drug sensitive
5-(4-Azido-3-chlorophenyl)-6-ethylpyrimidine-2,4-diamine 353605 Drug sensitive
Trimetrexate glucuronic acid salt 336805 Drug sensitive
Predorine 333830 Drug sensitive
4-Ethyl-6-methoxy-7-(oxiran-2-ylmethoxy)quinazoline 333565 Drug sensitive
Bishelenalinyl malonate 330973 Drug sensitive
Dmask 32465 Drug sensitive
Hydroxypristimerin 320914 Drug sensitive
5-Cinnamylidene-1,3-thiazolidine-2,4-dione 315044 Drug sensitive
2,3-Dimethoxy-5-naphthalen-2-ylsulfanylcyclohexa-2,5-diene-1,4-dione 314728 Drug sensitive
Daunorubicin 30323 Drug sensitive
1,1-Dimethyl-5-(2-naphthalenyl)dithiobiuret 3004012 Drug sensitive
P-Ara-C 282479 Drug sensitive
Cyclo-C 279062 Drug sensitive
2-Chloro-5-[4-[2-chloro-4-(4,6-diamino-2,2-dimethyl-1,3,5-triazin-1-yl)phenyl]butyl]benzenesulfonyl fluoride;ethanesulfonic acid 278692 Drug sensitive
Dichloroallyl lawsone 277767 Drug sensitive
6-Bromotoyocamycin 270861 Drug sensitive
Deoxycamptothecin 266552 Drug sensitive
1-(2-Chloroethyl)-3-(2,6-dioxo-3-piperidyl)-1-nitrosourea 26328 Drug sensitive
2,4,6-Trichloro-5-heptylpyrimidine 260791 Drug sensitive
Carmofur 2577 Drug sensitive
2'-Deoxy-5-(trifluoromethyl)uridine 253083 Drug sensitive
2,4,6-Trichloro-5-ethylpyrimidine 249455 Drug sensitive
9H-Purine, 6-(benzylthio)-9-(2-chloroethyl)- 246230 Drug sensitive
Antimycin A3 245869 Drug sensitive
Camptothecin 24360 Drug sensitive
N-[(4R)-4-[(3R,5R,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-Tris(3-aminopropoxy)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentyl]octan-1-amine 24205348 Drug sensitive
Mepacrine mustard dihydrochloride 24180972 Drug sensitive
9H-Purine, 2-amino-6-(o-chlorobenzylthio)-9-propyl- 239486 Drug sensitive
7-Fluoro-2-benzoyl-3-trifluoromethylquioxaline 1,4-dioxide 23635154 Drug sensitive
Amsacrine 2179 Drug sensitive
Diethylcarbamodithioic acid, sodium salt 21192315 Drug sensitive
Cladribine 20279 Drug sensitive
4-Chloro-5-phenoxy-3H-1,2-dithiole-3-thione 16766044 Drug sensitive
Azaribine 16574 Drug sensitive
Arypurine derivatives 16220246 Drug sensitive
GemMP[10] 16129935 Drug sensitive
1,2:5,6-Dianhydrogalactitol 15942827 Drug sensitive
2,6-Dibenzylidenecyclohexanone 1550330 Drug sensitive
(2Z,9E,13Z,15E)-4',11-Dihydroxy-2,4',9-trimethylspiro[3-aza-1(2,4)-thiazolacyclohexadecaphanene-6,3'-[1,2]dithiolane]-9,13,15-triene-4,5',12-trione 2'-oxide 154730760 Drug sensitive
(10S,13S,16S,19S)-16-Butan-2-yl-10,11,14-trimethyl-3-(oxiran-2-ylmethyl)-13-propan-2-yl-4-oxa-1,8,11,14,17-pentazabicyclo[17.3.0]docosane-2,5,9,12,15,18-hexone 152771884 Drug sensitive
Sulfanilanilide, 4'-(9-acridinylamino)- 148802 Drug sensitive
Ellipticine analog 148569 Drug sensitive
1H-2,10a-Ethanophenanthrene, kaur-16-en-15-one deriv. 146156727 Drug sensitive
Edelfosine 1392 Drug sensitive
Methyl (3'R)-3,4',9',10-tetrahydroxy-3'-[(2S,4R,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-7'-methoxy-5',8',9-trioxospiro[3,4-dihydropyrano[4,3-g]chromene-2,2'-3H-benzo[f][1]benzofuran]-7-carboxylate 137326876 Drug sensitive
C8, Carbonyl prodigiosine 135540857 Drug sensitive
Oxanthrazole 135502299 Drug sensitive
5-[(E)-[Amino(methyl)amino]azo]-1H-imidazole-4-carboxamide 135493930 Drug sensitive
Cysteine, S-[(4-aminocarbonyl-1H-imidazol-5-yl)azo]- 135493928 Drug sensitive
2-Methylpropyl (3Z)-2-oxo-3-[(4-sulfamoylanilino)methylidene]-1H-indole-5-carboxylate 135421141 Drug sensitive
8-Azahypoxanthine 135410720 Drug sensitive
2-Chloro-3-(2-butoxyethoxy)naphthazarin 135406263 Drug sensitive
Mercury, (4-aminophenyl)(6-thioguanosinato-N7,S6)- 135403617 Drug sensitive
Raltitrexed 135400182 Drug sensitive
DTIC-Dome 135398738 Drug sensitive
(1R,2S,5S,8S,9S,17R,18R,21S,24R,26S,27S)-14-Chloro-5,15-dihydroxy-2,9,26-trimethyl-3,19,23,28-tetraoxaoctacyclo[16.9.1.118,27.01,5.02,24.08,17.09,14.021,26]nonacos-11-ene-4,10,22,29-tetrone 134715214 Drug sensitive
[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-Diacetyloxy-1-hydroxy-15-[(2R,3S)-2-hydroxy-3-[[(E)-2-methylbut-2-enoyl]amino]-3-phenylpropanoyl]oxy-10,14,17,17-tetramethyl-11-oxo-9-[(3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxy-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate 134714918 Drug sensitive
Saintopin 131350 Drug sensitive
Sendanin 12806435 Drug sensitive
Terpentecin 127568 Drug sensitive
Octadecylphosphocholine 125219 Drug sensitive
(1S,3R,7Z,9R,12S,13R,15S)-13-Butan-2-yl-13-hydroxy-3,7,12-trimethyl-10,14,16-trioxatetracyclo[7.5.1.13,6.012,15]hexadeca-5,7-diene-4,11-dione 11972510 Drug sensitive
Cytochalasin q 11970174 Drug sensitive
Melampodinin 11953936 Drug sensitive
Indotecan 11533060 Drug sensitive
1-Phenyl-5-(4-(trifluoromethyl)phenyl)-1H-imidazole 11162021 Drug sensitive
p-Toluquinone 11122 Drug sensitive
Acetylenedicarboxamide 10971 Drug sensitive
6-[4-(1-Cyclohexenyl)-1,3-butadiyn-1-yl]-2(2H)-pyranone 10263039 Drug sensitive
(7S,9S)-7-[[(3As,4S,7aS)-1-[[(3aS,4S,7aS)-4-methyl-6-[[(1S,3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]-2,3a,4,6,7,7a-hexahydropyrano[4,3-d][1,3]oxazol-1-yl]methyl]-4-methyl-2,3a,4,6,7,7a-hexahydropyrano[4,3-d][1,3]oxazol-6-yl]oxy]-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione 101713728 Drug sensitive
(1S,2R,4R,6S,11R,12S,15R,18S,19R,20R,21S,23R,26R)-15-Hydroxy-11,18,21-trimethyl-5,17,24,28,29-pentaoxanonacyclo[17.9.1.11,20.02,12.04,6.06,11.015,19.018,23.021,26]triacont-8-ene-10,16,25,30-tetrone 101528280 Drug sensitive
Erigerol 101318126 Drug sensitive
N,N-Bis(2-chloroethyl)-p-toluidine 100400 Drug sensitive
Cinnoline, 4-nitro-, 1-oxide 100397 Drug sensitive
Tocladesine 100299 Drug sensitive
1,3-diphenyl-4-(3-phenyl-4,5-dihydro-1H-pyrazol-5-yl)-1H-pyrazole - Drug resistant
(1s,2e,4r,6r,7e,10r,11e)-2,7,11-cembratriene-4,6,10-triol - Drug sensitive
1,1'-biphenyl, 4,4'bis(thiomethyl)- - Drug sensitive
1h-1,2,4-triazole, 3-(4-diazo-4h-imidazol-5-yl)- - Drug sensitive
2,4,16-tribromoestra-1,3,5(10)-trien-3-ol-17-one - Drug sensitive
2-[(3,4-dicloro)anilino]-3-phenyl-5,7-diamino quinoxaline - Drug sensitive
3,19-benzylidine-14-deoxy-11,12-didehydroandrographolide - Drug sensitive
3,7-di(trifluoromethyl)-2-furoylquioxaline 1,4-dioxide - Drug sensitive
4'-deoxy-13',17-dinitro-3',4'-epoxy-vincaleukoblastine - Drug sensitive
4-piperidinone, 3,5-bis[(4-fluorophenyl)methylene]-, (e,e)- - Drug sensitive
7,10-acetonide of 14-hydroxy 10-deacetyl baccatin iii - Drug sensitive
7h-5,6-dithioleno[4,3-d]uracil - Drug sensitive
9,10-anthracenedione, 1-[(oxiranylmethyl)amino]- - Drug sensitive
b676297k277 3',4'-deoxypsorospermin 3',4'-chlorohydrin - Drug sensitive
benzene, 1,1'-[(1,3-butadiene-1,4-diyl)sulfonyl]bis - Drug sensitive
benzo[1,2-c:4,5-c']dipyrrole-1,3,5,7(2h,6h)-tetraimine - Drug sensitive
cis-2-hydroxymethyl-4-(isocytosin-1'-yl)-1,3-dioxolane - Drug sensitive
dimethylarsinothious acid, 2,4-pyrimidinediyl ester - Drug sensitive
ethanol, 2-[4-(2,2':6',2-terpyridin-4'-yl)phenoxy]- - Drug sensitive
ethyl, methoxy, prodigisine - Drug sensitive
ethyl-2,3-oxido-(5-bromo-2-methoxyphenyl)propionate - Drug sensitive
furan-2(3h)-one, 5-(4-methylphenyl)-3,3-diphenyl- - Drug sensitive
geldanamycin, n,n'-dimethyl - Drug sensitive
isoflavone, 5,7-dihydroxy-4'-nitro- - Drug sensitive
n,n'-bis(oxydiethylene)thiocarbamoylsulfenamide - Drug sensitive
phenol, 4,4'-(5,5'-biisoxazole-3,3'-diyl)bis- - Drug sensitive
propan-1-one, 2,3-dichloro-1,3-bis(4-methylphenyl)- - Drug sensitive
propanedinitrile, [(3,5-dibromo-2-ethoxyphenyl)methylene]- - Drug sensitive
pyrido[3',4':4,5]thieno[2,3-g]isoquinoline, 6-methyl- - Drug sensitive
pyrimidine, 2,4,5-trichloro-6-propyl- - Drug sensitive
salicylaldehyde, 5-bromo- (8ci) - Drug sensitive
tellurium, trichloro[1,2-hexanedioato(2-)-o,o']-, ammonium - Drug sensitive
tricyclo[4.4.0.0(2,7)]decane-5-one, 4,4-dibromo-2-methyl- - Drug sensitive
tris(1,3-diphenylpropane-1,3-dionata)gallium(iii) - Drug sensitive
(-)-dactylolide - Drug sensitive
[bis(aminomethyl)diethylsilane]dichloroplatinum (ii) - Drug sensitive
2'-o-(all trans)-retinoyl-erythromicine a - Drug sensitive
7-propanoyltaxol - Drug sensitive
Aminocamptothecin - Drug sensitive
analog of cc-1065 - Drug sensitive
Annamycin Liposomal - Drug sensitive
antibiotic a54556 - Drug sensitive
antineoplastic-624657 - Drug sensitive
antineoplastic-d665839 - Drug sensitive
Aphidicoline glycinate - Drug sensitive
arylpurine derivatives - Drug sensitive
Camptothecin Derivative - Drug sensitive
CI-921: amsacrine derivative - Drug sensitive
Copper(II) complex with quin as a ligand - Drug sensitive
devadarool (erthoxydiol-x) - Drug sensitive
erytroxytriol-p - Drug sensitive
Indenoisoquinoline derivative - Drug sensitive
insulin-methotrexate conjugate - Drug sensitive
largomycin f-ii - Drug sensitive
merophan - Drug sensitive
mitaplatin - Drug sensitive
o-linoleoyl-2-butoxy-1-desoamine - Drug sensitive
organosulfur compound - Drug sensitive
orlistat (usan) - Drug sensitive
phosphocitrate penta sodium salt - Drug sensitive
pyrazoline derivative - Drug sensitive
secafascaplysin - Drug sensitive
sphinxolide e - Drug sensitive
thiostrepton (usan) - Drug sensitive
trimethyl(phenylthio)stannane - Drug sensitive
Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-1224-5p
Imatinib 5291 Drug interaction    RC00007582
Doxorubicin 31703 Drug interaction    RC00007584
Hesperidin 10621 Drug interaction    RC00007583
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-1224-5p
Imatinib 5291       25349971

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-1224-5p
Interactor2: KMT2D

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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