Basic Information:

  VIRBase ID:  

HHID00068153

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-374b-3p:  MIMAT0004956          LDHD:  NM_153486     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-374b-3p	LDHD
miRBase Accession/Entrez ID	MIMAT0004956	197257
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	DLACD//DLD

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	LDHD	chr16:75145865-75145866(-) m6A 3'UTR       24284625//25456834//24981863 chr16:75145893-75145894(-) m6A 3'UTR       24284625//25456834//24981863 chr16:75145941-75145942(-) m6A 3'UTR       24284625//25456834//24981863 chr16:75146198-75146199(-) m6A 3'UTR       24284625 chr16:75146290-75146291(-) m6A CDS       24284625 chr16:75146318-75146319(-) m6A CDS       24284625 chr16:75146510-75146511(-) m6A CDS       24284625//27773536 chr16:75146537-75146538(-) m6A CDS       24284625//27773536 chr16:75146738-75146739(-) m6A CDS       - chr16:75148807-75148808(-) m6A 3'UTR//CDS//exon       - chr16:75148816-75148817(-) m6A 3'UTR//CDS//exon       - chr16:75148834-75148835(-) m6A 3'UTR//CDS//exon       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-374b-3p	Exosome Plasma     23663360 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
	LDHD	Exosome Blood     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-374b-3p
Interactor2: LDHD

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.