Detail Information

Basic Information:


  VIRBase ID:  

HHID00068133

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-374b-3p:           KIF21A:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-374b-3p KIF21A
miRBase
Accession/Entrez ID		 MIMAT0004956 55605
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - CFEOM1//FEOM1//FEOM3A

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR KIF21A
chr12:39719416(-) A-I      intronic
chr12:39719410(-) A-I      intronic
chr12:39826601(-) A-I      intronic
chr12:39719382(-) A-I      intronic
chr12:39719374(-) A-I      intronic
chr12:39824202(-) A-I      intronic
chr12:39824196(-) A-I      intronic
chr12:39824176(-) A-I      intronic
chr12:39824123(-) A-I      intronic
chr12:39822718(-) A-I      intronic
chr12:39822644(-) A-I      intronic
chr12:39822597(-) A-I      intronic
chr12:39821742(-) A-I      intronic
chr12:39821734(-) A-I      intronic
chr12:39821685(-) A-I      intronic
chr12:39821679(-) A-I      intronic
chr12:39821553(-) A-I      intronic
chr12:39820578(-) A-I      intronic
chr12:39816054(-) A-I      intronic
chr12:39816021(-) A-I      intronic
chr12:39815395(-) A-I      intronic
chr12:39774988(-) A-I      intronic
chr12:39811974(-) A-I      intronic
chr12:39811792(-) A-I      intronic
chr12:39810286(-) A-I      intronic
chr12:39810274(-) A-I      intronic
chr12:39809206(-) A-I      intronic
chr12:39806434(-) A-I      intronic
chr12:39806289(-) A-I      intronic
chr12:39803772(-) A-I      intronic
chr12:39803241(-) A-I      intronic
chr12:39803239(-) A-I      intronic
chr12:39803104(-) A-I      intronic
chr12:39803087(-) A-I      intronic
chr12:39802923(-) A-I      intronic
chr12:39802837(-) A-I      intronic
chr12:39785368(-) A-I      intronic
chr12:39774975(-) A-I      intronic
chr12:39774863(-) A-I      intronic
chr12:39757708(-) A-I      intronic
chr12:39757698(-) A-I      intronic
chr12:39757696(-) A-I      intronic
chr12:39729948(-) A-I      intronic
chr12:39719434(-) A-I      intronic
chr12:39719272(-) A-I      intronic
chr12:39719262(-) A-I      intronic
chr12:39815383(-) A-I      intronic
chr12:39824329(-) A-I      intronic
chr12:39824292(-) A-I      intronic
chr12:39824213(-) A-I      intronic
chr12:39719395(-) A-I      intronic
chr12:39815925(-) A-I      intronic
chr12:39805733(-) A-I      intronic
chr12:39807570(-) A-I      intronic
chr12:39806390(-) A-I      intronic
chr12:39803754(-) A-I      intronic
chr12:39810276(-) A-I      intronic
chr12:39719205(-) A-I      intronic
chr12:39815889(-) A-I      intronic
chr12:39821585(-) A-I      intronic
chr12:39822677(-) A-I      intronic
chr12:39826637(-) A-I      intronic
chr12:39809147(-) A-I      intronic
chr12:39699209(-) A-I      intronic
chr12:39809180(-) A-I      intronic
chr12:39773037(-) A-I      intronic
chr12:39719230(-) A-I      intronic
chr12:39809237(-) A-I      intronic
chr12:39821640(-) A-I      intronic
chr12:39806518(-) A-I      intronic
chr12:39815909(-) A-I      intronic
chr12:39822678(-) A-I      intronic
chr12:39815944(-) A-I      intronic
chr12:39815899(-) A-I      intronic
chr12:39774466(-) A-I      intronic
chr12:39805801(-) A-I      intronic
chr12:39805576(-) A-I      intronic
chr12:39815408(-) A-I      intronic
chr12:39714573(-) A-I      intronic
chr12:39809284(-) A-I      intronic
chr12:39719351(-) A-I      intronic
chr12:39834786(-) A-I      intronic
chr12:39806336(-) A-I      intronic
chr12:39815332(-) A-I      intronic
chr12:39802719(-) A-I      intronic
chr12:39773047(-) A-I      intronic
chr12:39815979(-) A-I      intronic
chr12:39719226(-) A-I      intronic
chr12:39805467(-) A-I      intronic
chr12:39803802(-) A-I      intronic
chr12:39802714(-) A-I      intronic
chr12:39809217(-) A-I      intronic
chr12:39785812(-) A-I      intronic
chr12:39719350(-) A-I      intronic
chr12:39820564(-) A-I      intronic
chr12:39774986(-) A-I      intronic
chr12:39806396(-) A-I      intronic
chr12:39815373(-) A-I      intronic
chr12:39805839(-) A-I      intronic
chr12:39699130(-) A-I      intronic
chr12:39806468(-) A-I      intronic
chr12:39805586(-) A-I      intronic
chr12:39797941(-) A-I      intronic
chr12:39803137(-) A-I      intronic
chr12:39699283(-) A-I      intronic
chr12:39806444(-) A-I      intronic
chr12:39803298(-) A-I      intronic
chr12:39806482(-) A-I      intronic
chr12:39807576(-) A-I      intronic
chr12:39806314(-) A-I      intronic
chr12:39821707(-) A-I      intronic
chr12:39810132(-) A-I      intronic
chr12:39805775(-) A-I      intronic
chr12:39727920(-) A-I      intronic
chr12:39834765(-) A-I      intronic
chr12:39802896(-) A-I      intronic
chr12:39802889(-) A-I      intronic
chr12:39805693(-) A-I      intronic
chr12:39826655(-) A-I      intronic
chr12:39834811(-) A-I      intronic
chr12:39815409(-) A-I      intronic
chr12:39699306(-) A-I      intronic
chr12:39699314(-) A-I      intronic
chr12:39815432(-) A-I      intronic
chr12:39802858(-) A-I      intronic
chr12:39803249(-) A-I      intronic
chr12:39815412(-) A-I      intronic
chr12:39805880(-) A-I      intronic
chr12:39821558(-) A-I      intronic
chr12:39719210(-) A-I      intronic
chr12:39820604(-) A-I      intronic
chr12:39805729(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED KIF21A
chr12:39773037(-) A-G intron -    22484847
chr12:39773047(-) A-G intron -    22484847
chr12:39773106(-) T-C intron -    22484847
chr12:39774466(-) A-G intron -    22484847
chr12:39774986(-) A-G intron -    22484847
chr12:39785812(-) A-G intron -    22484847
chr12:39802714(-) A-G intron -    22484847
chr12:39802719(-) A-G intron -    22484847
chr12:39802858(-) A-G intron -    22484847
chr12:39802889(-) A-G intron -    22484847
chr12:39802896(-) A-G intron -    22484847
chr12:39803137(-) A-G intron -    22484847
chr12:39803249(-) A-G intron -    22484847
chr12:39803754(-) A-G intron -    22484847
chr12:39805775(-) A-G intron -    22484847
chr12:39805801(-) A-G intron -    22484847
chr12:39805880(-) A-G intron -    22484847
chr12:39806390(-) A-G intron -    22484847
chr12:39806444(-) A-G intron -    22484847
chr12:39806482(-) A-G intron -    22484847
chr12:39806518(-) A-G intron -    22484847
chr12:39810276(-) A-G intron -    22484847
chr12:39815373(-) A-G intron -    22484847
chr12:39815408(-) A-G intron -    22484847
chr12:39815409(-) A-G intron -    22484847
chr12:39815412(-) A-G intron -    22484847
chr12:39815925(-) A-G intron -    22484847
chr12:39820564(-) A-G intron -    22484847
chr12:39820604(-) A-G intron -    22484847
chr12:39821558(-) A-G intron -    22484847
chr12:39821585(-) A-G intron -    22484847
chr12:39821640(-) A-G intron -    22484847
chr12:39821707(-) A-G intron -    22484847
chr12:39822678(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase KIF21A
chr12:39687047-39687048(-) m6A 3'UTR//exon       27773535
chr12:39687068-39687069(-) m6A 3'UTR//exon       27773535
chr12:39706208-39706209(-) m6A exon//intron       27773535
chr12:39711933-39711934(-) m6A CDS//intron       27773535
chr12:39711989-39711990(-) m6A CDS//intron       27773535
chr12:39713715-39713716(-) m6A 3'UTR//CDS       27773535
chr12:39716539-39716540(-) m6A CDS//intron       -
chr12:39716619-39716620(-) m6A CDS//intron       -
chr12:39716630-39716631(-) m6A CDS//intron       -
chr12:39726032-39726033(-) Cm CDS       -
chr12:39726177-39726178(-) m6A CDS       24981863//27773535
chr12:39726198-39726199(-) m6A CDS       24981863//27773535
chr12:39726401-39726402(-) m6A CDS       24981863//27773535
chr12:39726453-39726454(-) m6A CDS       24981863//27773535
chr12:39726496-39726497(-) m6A CDS       24981863//27773535
chr12:39726697-39726698(-) m6A CDS       27773535
chr12:39726882-39726883(-) m6A CDS//exon       27773535
chr12:39727021-39727022(-) m6A CDS//exon//intron       27773535
chr12:39727047-39727048(-) m6A CDS//exon//intron       24981863//27773535
chr12:39727070-39727071(-) m6A CDS//exon//intron       24981863//27773535
chr12:39730940-39730941(-) m6A CDS//exon       24981863//27773535//22608085
chr12:39730960-39730961(-) m6A CDS//exon       24981863//27773535//22608085
chr12:39730975-39730976(-) m6A CDS//exon       24981863//27773535//22608085
chr12:39730990-39730991(-) m6A CDS//exon       24981863//27773535//22608085
chr12:39731084-39731085(-) m6A exon//intron       24981863//27773535
chr12:39731122-39731123(-) m6A exon//intron       27773535
chr12:39733971-39733972(-) m6A CDS       24981863//27773535
chr12:39734053-39734054(-) m6A CDS       24981863//27773535
chr12:39734074-39734075(-) m6A CDS       24981863//27773535
chr12:39734083-39734084(-) m6A CDS       24981863//27773535
chr12:39734090-39734091(-) m6A CDS       24981863//27773535
chr12:39734104-39734105(-) m6A CDS       24981863//27773535
chr12:39734712-39734713(-) m6A CDS       24981863//27773535
chr12:39734727-39734728(-) m6A CDS       24981863//27773535
chr12:39734800-39734801(-) m6A CDS       24981863//27773535
chr12:39734807-39734808(-) m6A CDS       24981863//27773535
chr12:39734820-39734821(-) m6A CDS       24981863//27773535
chr12:39734828-39734829(-) m6A CDS       24981863//27773535
chr12:39734871-39734872(-) m6A CDS       24981863//27773535
chr12:39734880-39734881(-) m6A CDS       24981863//27773535
chr12:39735386-39735387(-) m1A CDS       26863196
chr12:39735851-39735852(-) m6A CDS       24284625//24981863//27773535//22575960//22608085
chr12:39735899-39735900(-) m6A CDS       24284625//24981863//27773535//22575960//22608085
chr12:39740296-39740297(-) m6A CDS//intron       24284625//24981863//27773535//22608085
chr12:39745635-39745636(-) m6A CDS       24981863//27773535//22608085
chr12:39745651-39745652(-) m6A CDS       24981863//27773535
chr12:39745659-39745660(-) m6A CDS       24981863//27773535
chr12:39745734-39745735(-) m6A CDS       24981863//27773535
chr12:39745746-39745747(-) m6A CDS       24981863//27773535
chr12:39751166-39751167(-) m6A CDS       24981863//27773535
chr12:39751981-39751982(-) m6A CDS       24981863//27773535//22575960
chr12:39752055-39752056(-) m6A CDS       24981863//27773535
chr12:39752115-39752116(-) m6A CDS       24981863//26404942//27773535
chr12:39752133-39752134(-) m6A CDS       24981863//26404942//27773535
chr12:39752139-39752140(-) m6A CDS       24981863//26404942//27773535
chr12:39752170-39752171(-) m6A CDS       24981863//27773535
chr12:39756928-39756929(-) m6A CDS       24981863//27773535
chr12:39764056-39764057(-) m6A CDS       27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-374b-3p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
KIF21A
Chromatin K562 cells     -
Cytosol HCC cell line (HepG2)|K562 cells     -
Exosome Blood     -
Membrane K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)|HeLa-S3 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-374b-3p
Interactor2: KIF21A

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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