Detail Information

Basic Information:


  VIRBase ID:  

HHID00068122

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-374b-3p:           KIFAP3:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-374b-3p KIFAP3
miRBase
Accession/Entrez ID		 MIMAT0004956 22920
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - dJ190I16.1//FLA3//KAP-1//KAP-3//KAP3//SMAP//Smg-GDS

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR KIFAP3
chr1:169991187(-) A-I      intronic
chr1:169991196(-) A-I      intronic
chr1:169991173(-) A-I      intronic
chr1:169991180(-) A-I      intronic
chr1:169991183(-) A-I      intronic
chr1:169966887(-) A-I      intronic
chr1:169966883(-) A-I      intronic
chr1:169991156(-) A-I      intronic
chr1:169897776(-) A-I      intronic
chr1:170034565(-) A-I      intronic
chr1:169932666(-) A-I      intronic
chr1:169962386(-) A-I      intronic
chr1:169966849(-) A-I      intronic
chr1:169962914(-) A-I      intronic
chr1:169966777(-) A-I      intronic
chr1:169991261(-) A-I      intronic
chr1:169989784(-) A-I      intronic
chr1:169989727(-) A-I      intronic
chr1:169989686(-) A-I      intronic
chr1:169989790(-) A-I      intronic
chr1:169962412(-) A-I      intronic
chr1:169989785(-) A-I      intronic
chr1:169991148(-) A-I      intronic
chr1:169989700(-) A-I      intronic
chr1:169962818(-) A-I      intronic
chr1:169897680(-) A-I      intronic
chr1:169897692(-) A-I      intronic
chr1:169897769(-) A-I      intronic
chr1:169962854(-) A-I      intronic
chr1:169897706(-) A-I      intronic
chr1:169962982(-) A-I      intronic
chr1:169962943(-) A-I      intronic
chr1:169924897(-) A-I      intronic
chr1:169962523(-) A-I      intronic
chr1:169897419(-) A-I      intronic
chr1:169962902(-) A-I      intronic
chr1:169897586(-) A-I      intronic
chr1:169986375(-) A-I      intronic
chr1:169897689(-) A-I      intronic
chr1:169897606(-) A-I      intronic
chr1:169897405(-) A-I      intronic
chr1:169897726(-) A-I      intronic
chr1:169991264(-) A-I      intronic
chr1:169962925(-) A-I      intronic
chr1:169962891(-) A-I      intronic
chr1:169897629(-) A-I      intronic
chr1:169900249(-) A-I      intronic
chr1:169962399(-) A-I      intronic
chr1:169897338(-) A-I      intronic
chr1:169962524(-) A-I      intronic
chr1:169986290(-) A-I      intronic
chr1:169989826(-) A-I      intronic
chr1:169962946(-) A-I      intronic
chr1:169962917(-) A-I      intronic
chr1:169897669(-) A-I      intronic
chr1:170010600(-) A-I      intronic
chr1:169962346(-) A-I      intronic
chr1:169991228(-) A-I      intronic
chr1:169962381(-) A-I      intronic
chr1:169924906(-) A-I      intronic
chr1:169962815(-) A-I      intronic
chr1:169924893(-) A-I      intronic
chr1:169986286(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED KIFAP3
chr1:169897255(-) G-A intron -    22484847
chr1:169897405(-) A-G intron -    22484847
chr1:169897419(-) A-G intron -    22484847
chr1:169900249(-) A-G intron -    22484847
chr1:169962346(-) A-G intron -    22484847
chr1:169962381(-) A-G intron -    22484847
chr1:169962399(-) A-G intron -    22484847
chr1:169962815(-) A-G intron -    22484847
chr1:169962854(-) A-G intron -    22484847
chr1:169962891(-) A-G intron -    22484847
chr1:169962902(-) A-G intron -    22484847
chr1:169962917(-) A-G intron -    22484847
chr1:169962925(-) A-G intron -    22484847
chr1:169962943(-) A-G intron -    22484847
chr1:169962982(-) A-G intron -    22484847
chr1:169986286(-) A-G intron -    22484847
chr1:170010600(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase KIFAP3
chr1:169941717-169941718(-) m6A CDS       27773535
chr1:169947228-169947229(-) m6A CDS       27773535
chr1:170043714-170043715(-) m6A 5'UTR//intron       24284625//24981863//27371828

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-374b-3p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
KIFAP3
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol K562 cells     -
Exosome Blood     -
Nucleus HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-374b-3p
Interactor2: KIFAP3

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region CDS
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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