Detail Information

Basic Information:


  VIRBase ID:  

HHID00068120

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-374b-3p:           EIF3M:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-374b-3p EIF3M
miRBase
Accession/Entrez ID		 MIMAT0004956 10480
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - B5//GA17//hfl-B5//PCID1//TANGO7

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR EIF3M
chr11:32625546(+) A-I      3'UTR
chr11:32625419(+) A-I      3'UTR
chr11:32625443(+) A-I      3'UTR
chr11:32625437(+) A-I      3'UTR
chr11:32625442(+) A-I      3'UTR
chr11:32625357(+) A-I      3'UTR
chr11:32625972(+) A-I      3'UTR
chr11:32625450(+) A-I      3'UTR
chr11:32625460(+) A-I      3'UTR
chr11:32625515(+) A-I      3'UTR
chr11:32625525(+) A-I      3'UTR
chr11:32616852(+) A-I      intronic
chr11:32616876(+) A-I      intronic
chr11:32609814(+) A-I      intronic
chr11:32618237(+) A-I      intronic
chr11:32618097(+) A-I      intronic
chr11:32609788(+) A-I      intronic
chr11:32625498(+) A-I      3'UTR
chr11:32625521(+) A-I      3'UTR
chr11:32625538(+) A-I      3'UTR
chr11:32625554(+) A-I      3'UTR
chr11:32625359(+) A-I      3'UTR
chr11:32625558(+) A-I      3'UTR
chr11:32625562(+) A-I      3'UTR
chr11:32625563(+) A-I      3'UTR
chr11:32625568(+) A-I      3'UTR
chr11:32625578(+) A-I      3'UTR
chr11:32625863(+) A-I      3'UTR
chr11:32625593(+) A-I      3'UTR
chr11:32625595(+) A-I      3'UTR
chr11:32625597(+) A-I      3'UTR
chr11:32625613(+) A-I      3'UTR
chr11:32625688(+) A-I      3'UTR
chr11:32625692(+) A-I      3'UTR
chr11:32625827(+) A-I      3'UTR
chr11:32625732(+) A-I      3'UTR
chr11:32625733(+) A-I      3'UTR
chr11:32625822(+) A-I      3'UTR
chr11:32625811(+) A-I      3'UTR
chr11:32625422(+) A-I      3'UTR
chr11:32625796(+) A-I      3'UTR
chr11:32625788(+) A-I      3'UTR
chr11:32625769(+) A-I      3'UTR
chr11:32625730(+) A-I      3'UTR
chr11:32626538(+) A-I      3'UTR
chr11:32625371(+) A-I      3'UTR
chr11:32625765(+) A-I      3'UTR
chr11:32625353(+) A-I      3'UTR
chr11:32625755(+) A-I      3'UTR
chr11:32625388(+) A-I      3'UTR
chr11:32625406(+) A-I      3'UTR
chr11:32625411(+) A-I      3'UTR
chr11:32626583(+) A-I      3'UTR
chr11:32625431(+) A-I      3'UTR
chr11:32625748(+) A-I      3'UTR
chr11:32625482(+) A-I      3'UTR
chr11:32625435(+) A-I      3'UTR
chr11:32625743(+) A-I      3'UTR
chr11:32625919(+) A-I      3'UTR
chr11:32625445(+) A-I      3'UTR
chr11:32625461(+) A-I      3'UTR
chr11:32625463(+) A-I      3'UTR
chr11:32625738(+) A-I      3'UTR
chr11:32626580(+) A-I      3'UTR
chr11:32626516(+) A-I      3'UTR
chr11:32625592(+) A-I      3'UTR
chr11:32625420(+) A-I      3'UTR
chr11:32626499(+) A-I      3'UTR
chr11:32626492(+) A-I      3'UTR
chr11:32625892(+) A-I      3'UTR
chr11:32626479(+) A-I      3'UTR
chr11:32625343(+) A-I      3'UTR
chr11:32626589(+) A-I      3'UTR
chr11:32626473(+) A-I      3'UTR
chr11:32625809(+) A-I      3'UTR
chr11:32625836(+) A-I      3'UTR
chr11:32626468(+) A-I      3'UTR
chr11:32626424(+) A-I      3'UTR
chr11:32626597(+) A-I      3'UTR
chr11:32626678(+) A-I      3'UTR
chr11:32626609(+) A-I      3'UTR
chr11:32625936(+) A-I      3'UTR
chr11:32625931(+) A-I      3'UTR
chr11:32625917(+) A-I      3'UTR
chr11:32625891(+) A-I      3'UTR
chr11:32625474(+) A-I      3'UTR
chr11:32626660(+) A-I      3'UTR
chr11:32616959(+) A-I      intronic
chr11:32617975(+) A-I      intronic
chr11:32617994(+) A-I      intronic
chr11:32616956(+) A-I      intronic
chr11:32606162(+) A-I      intronic
chr11:32607566(+) A-I      intronic
chr11:32609665(+) A-I      intronic
chr11:32618020(+) A-I      intronic
chr11:32625384(+) A-I      3'UTR
chr11:32625462(+) A-I      3'UTR
chr11:32625918(+) A-I      3'UTR
chr11:32625492(+) A-I      3'UTR
chr11:32625555(+) A-I      3'UTR
chr11:32625522(+) A-I      3'UTR
chr11:32625421(+) A-I      3'UTR
chr11:32625365(+) A-I      3'UTR
chr11:32625700(+) A-I      3'UTR
chr11:32625528(+) A-I      3'UTR
chr11:32625382(+) A-I      3'UTR
chr11:32625383(+) A-I      3'UTR
chr11:32625687(+) A-I      3'UTR
chr11:32625925(+) A-I      3'UTR
chr11:32625533(+) A-I      3'UTR
chr11:32625366(+) A-I      3'UTR
chr11:32625466(+) A-I      3'UTR
chr11:32625708(+) A-I      3'UTR

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase EIF3M
chr11:32605467-32605468(+) m1A 5'UTR//CDS//exon       26863196//26863410
chr11:32610157-32610158(+) m6A 3'UTR//CDS//exon//intron       26404942//22575960
chr11:32610188-32610189(+) m6A 3'UTR//CDS//exon//intron       26404942//22575960
chr11:32610193-32610194(+) m6A 3'UTR//CDS//exon//intron       26404942//22575960
chr11:32611151-32611152(+) m6A 3'UTR//CDS//exon       27773535
chr11:32622247-32622248(+) m6A 3'UTR//CDS//exon       26404942//27773535
chr11:32622268-32622269(+) m6A 3'UTR//CDS//exon       26404942//27773535//22575960
chr11:32622334-32622335(+) m6A 3'UTR//CDS//exon       26404942//27773535//22575960
chr11:32622387-32622388(+) m6A 3'UTR//intron       26404942//27773535
chr11:32622392-32622393(+) m6A 3'UTR//intron       26404942//27773535
chr11:32622458-32622459(+) m6A 3'UTR//intron       27773535
chr11:32623031-32623032(+) m6A 3'UTR//intron       27773535
chr11:32623315-32623316(+) m6A CDS//exon       27773535
chr11:32623345-32623346(+) m6A CDS//exon       27773535
chr11:32623840-32623841(+) m6A CDS//exon       26404942//27773535
chr11:32623851-32623852(+) m6A CDS       26404942//27773535
chr11:32623893-32623894(+) m6A CDS       27773535
chr11:32623904-32623905(+) m6A CDS       27773535
chr11:32623916-32623917(+) m6A CDS       27773535
chr11:32624000-32624001(+) m6A 3'UTR       27773535
chr11:32624009-32624010(+) m6A 3'UTR       27773535

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-374b-3p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
EIF3M
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol K562 cells     -
Exosome Blood     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -
Ribosome HEK-293 cells     22199352
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-374b-3p
Interactor2: EIF3M

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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