Detail Information

Basic Information:


  VIRBase ID:  

HHID00068115

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-374b-3p:           NAPG:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-374b-3p NAPG
miRBase
Accession/Entrez ID		 MIMAT0004956 8774
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - GAMMASNAP

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR NAPG
chr18:10535638(+) A-I      intronic
chr18:10537176(+) A-I      intronic
chr18:10535494(+) A-I      intronic
chr18:10537066(+) A-I      intronic
chr18:10535503(+) A-I      intronic
chr18:10535599(+) A-I      intronic
chr18:10537218(+) A-I      intronic
chr18:10537139(+) A-I      intronic
chr18:10545051(+) A-I      intronic
chr18:10537033(+) A-I      intronic
chr18:10537017(+) A-I      intronic
chr18:10537165(+) A-I      intronic
chr18:10537119(+) A-I      intronic
chr18:10537191(+) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED NAPG
chr18:10551106(+) A-T intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase NAPG
chr18:10526085-10526086(+) m6A 5'UTR       24981863
chr18:10526131-10526132(+) m6A CDS//exon       24981863
chr18:10526410-10526411(+) m6A 5'UTR//intron       24981863
chr18:10540410-10540411(+) m6A exon//intron       24981863
chr18:10540768-10540769(+) m6A exon//intron       24981863
chr18:10549005-10549006(+) m6A 3'UTR//CDS//exon       -
chr18:10549034-10549035(+) m6A 3'UTR//CDS//exon       24981863
chr18:10549085-10549086(+) m6A 3'UTR//CDS//exon       24284625//24209618//24981863//22608085
chr18:10550207-10550208(+) m6A 3'UTR//CDS//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr18:10550245-10550246(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr18:10550278-10550279(+) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//22608085
chr18:10550341-10550342(+) m6A 3'UTR//exon       24284625//24981863
chr18:10551663-10551664(+) Y 3'UTR//exon       26075521

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-374b-3p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
NAPG
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-374b-3p
Interactor2: NAPG

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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