Detail Information

Basic Information:


  VIRBase ID:  

HHID00068109

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-374b-3p:           DYNLT1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-374b-3p DYNLT1
miRBase
Accession/Entrez ID		 MIMAT0004956 6993
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - CW-1//TCTEL1//tctex-1//TCTEX1

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR DYNLT1
chr6:159064785(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase DYNLT1
chr6:159057730-159057731(-) m6A 3'UTR       24284625//26404942
chr6:159057783-159057784(-) m6A 3'UTR       24284625//24981863//26404942
chr6:159057870-159057871(-) m6A 3'UTR//CDS       24284625//24981863
chr6:159057899-159057900(-) m6A 3'UTR//CDS       24284625
chr6:159058818-159058819(-) m6A 5'UTR//CDS       24284625//24209618//24981863//27773535//27371828//22608085
chr6:159058851-159058852(-) m6A 5'UTR//CDS       24284625//24209618//24981863//27773535//27371828//22608085
chr6:159058868-159058869(-) m6A 5'UTR//CDS       24284625//24209618//24981863//27773535//27371828//22608085
chr6:159058876-159058877(-) m6A 5'UTR//CDS       24284625//24209618//24981863//27773535//27371828//22608085
chr6:159062391-159062392(-) m6A 5'UTR//CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22608085
chr6:159062417-159062418(-) m6A 5'UTR//intron       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chr6:159062519-159062520(-) m6A 5'UTR//intron       25456834
chr6:159065732-159065733(-) m6A CDS       24209618//24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-374b-3p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
DYNLT1
Chromatin K562 cells     -
Exosome Blood     -
Nucleoplasm K562 cells     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-374b-3p
Interactor2: DYNLT1

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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