Basic Information:

  VIRBase ID:  

HHID00067729

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-33b-3p:  MIMAT0004811          BCCIP:  NM_016567     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-33b-3p	BCCIP
miRBase Accession/Entrez ID	MIMAT0004811	56647
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	TOK-1//TOK1

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-33b-3p	rs1014636340 chr17:17813869    C/T rs1175344913 chr17:17813860    C/T rs1212055173 chr17:17813859    G/C rs1333766161 chr17:17813870    G/A rs1359466877 chr17:17813864    A/G rs751021350 chr17:17813857    G/A rs1272832890 chr17:17813873    G/A rs1296048342 chr17:17813872    G/A rs1399118390 chr17:17813874    C/T

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	BCCIP	chr10:127540439(+) A-I      intronic chr10:127540466(+) A-I      intronic chr10:127540455(+) A-I      intronic chr10:127540445(+) A-I      intronic chr10:127523165(+) A-I      intronic chr10:127523166(+) A-I      intronic chr10:127540431(+) A-I      intronic chr10:127540418(+) A-I      intronic chr10:127526135(+) A-I      intronic chr10:127526125(+) A-I      intronic chr10:127540387(+) A-I      intronic chr10:127540379(+) A-I      intronic chr10:127538983(+) A-I      intronic chr10:127523176(+) A-I      intronic chr10:127526121(+) A-I      intronic chr10:127526076(+) A-I      intronic chr10:127526071(+) A-I      intronic chr10:127523147(+) A-I      intronic chr10:127523134(+) A-I      intronic chr10:127521437(+) A-I      intronic chr10:127520881(+) A-I      intronic chr10:127523682(+) A-I      intronic chr10:127526097(+) A-I      intronic chr10:127526083(+) A-I      intronic chr10:127521522(+) A-I      intronic chr10:127521720(+) A-I      intronic chr10:127521500(+) A-I      intronic chr10:127521406(+) A-I      intronic chr10:127521452(+) A-I      intronic chr10:127538589(+) A-I      intronic chr10:127521242(+) A-I      intronic chr10:127538594(+) A-I      intronic chr10:127520843(+) A-I      intronic chr10:127538668(+) A-I      intronic chr10:127521429(+) A-I      intronic chr10:127521469(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	BCCIP	chr10:127520843(+) A-I intron -    21960545 chr10:127520848(+) A-I intron -    21960545 chr10:127521452(+) A-G intron -    22484847 chr10:127521469(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	BCCIP	chr10:127514101-127514102(+) m6A exon//intron       25456834//24981863//27773535 chr10:127522413-127522414(+) m6A CDS       24981863//27773535 chr10:127522435-127522436(+) m6A CDS       24981863//27773535 chr10:127522451-127522452(+) m6A CDS       24981863//27773535 chr10:127524771-127524772(+) m6A CDS//intron       24284625//24209618//24981863//26404942//27773535//22608085 chr10:127524818-127524819(+) m6A CDS//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr10:127524857-127524858(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr10:127524893-127524894(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085 chr10:127524916-127524917(+) m6A 3'UTR//intron       24284625//24209618//24981863//27773535//22575960//22608085 chr10:127524922-127524923(+) m6A 3'UTR//intron       24284625//24209618//24981863//27773535//22575960//22608085 chr10:127525041-127525042(+) m6A 3'UTR//intron       27773535//22608085 chr10:127525084-127525085(+) m6A 3'UTR//intron       27773535 chr10:127525095-127525096(+) m6A 3'UTR//intron       27773535 chr10:127529834-127529835(+) m6A CDS       27773535 chr10:127529857-127529858(+) m6A CDS       27773535 chr10:127529934-127529935(+) m6A 3'UTR//intron       24981863 chr10:127529975-127529976(+) m6A 3'UTR//intron       24981863 chr10:127530003-127530004(+) m6A 3'UTR//intron       24981863 chr10:127530377-127530378(+) m6A 3'UTR//intron       24284625//24981863//22608085 chr10:127530404-127530405(+) m6A 3'UTR//intron       24284625//24981863//22608085 chr10:127530492-127530493(+) m6A 3'UTR//intron       24284625//24981863//22608085 chr10:127530557-127530558(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//22608085 chr10:127530568-127530569(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//22608085 chr10:127530588-127530589(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//22608085 chr10:127530596-127530597(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//22608085 chr10:127530603-127530604(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//22608085 chr10:127530617-127530618(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//22608085 chr10:127530678-127530679(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//22608085 chr10:127530754-127530755(+) m6A 3'UTR//intron       24284625//24209618//24981863//22608085 chr10:127530792-127530793(+) m6A 3'UTR//intron       24284625//24209618//24981863//22608085 chr10:127530814-127530815(+) m6A 3'UTR//intron       24284625//24209618//24981863//22608085 chr10:127530829-127530830(+) m6A 3'UTR//intron       24284625//24209618//24981863//22608085 chr10:127530855-127530856(+) m6A 3'UTR//intron       24284625//24209618//24981863//22608085 chr10:127530938-127530939(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//22608085 chr10:127530983-127530984(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//22608085 chr10:127531002-127531003(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//22608085 chr10:127531041-127531042(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//22608085 chr10:127531072-127531073(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27773535//22608085 chr10:127531085-127531086(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27773535//22608085 chr10:127531127-127531128(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27773535//22608085 chr10:127531155-127531156(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27773535//22608085 chr10:127531179-127531180(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//27773535//22608085 chr10:127531325-127531326(+) m6A 3'UTR//intron       24981863//27773535//22608085 chr10:127542092-127542093(+) m6A 3'UTR       27773535 chr10:127542200-127542201(+) m6A 3'UTR       27773535

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-33b-3p	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Fibroblasts|Mesenchymal stem cells     -
	BCCIP	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)     - Exosome Blood     - Membrane HCC cell line (HepG2)     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HeLa-S3 cells     - Ribosome Colon cancer cells     24393600

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID	PMID
NoncoRNA	hsa-miR-33b-3p	Cisplatin 5702198       27559850

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-33b-3p
Interactor2: BCCIP

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.