Detail Information

Basic Information:


  VIRBase ID:  

HHID00067544

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-616-3p:           KLHL28:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-616-3p KLHL28
miRBase
Accession/Entrez ID		 MIMAT0004805 54813
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - BTBD5

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-616-3p
rs374321661 chr12:57519192    C/T
rs573303396 chr12:57519190    A/C
rs573303396 chr12:57519190    A/G
rs760442491 chr12:57519183    C/T
rs763282175 chr12:57519193    C/T
rs768469143 chr12:57519184    T/C
rs776483081 chr12:57519185    G/A
rs368928238 chr12:57519199    A/G
rs377525107 chr12:57519198    A/C
rs755336783 chr12:57519200    T/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR KLHL28
chr14:45406451(-) A-I      intronic
chr14:45410120(-) A-I      intronic
chr14:45410131(-) A-I      intronic
chr14:45412784(-) A-I      intronic
chr14:45410134(-) A-I      intronic
chr14:45415760(-) A-I      intronic
chr14:45421329(-) A-I      intronic
chr14:45410137(-) A-I      intronic
chr14:45410163(-) A-I      intronic
chr14:45410675(-) A-I      intronic
chr14:45410755(-) A-I      intronic
chr14:45407703(-) A-I      intronic
chr14:45407707(-) A-I      intronic
chr14:45410769(-) A-I      intronic
chr14:45407713(-) A-I      intronic
chr14:45412797(-) A-I      intronic
chr14:45412808(-) A-I      intronic
chr14:45424906(-) A-I      intronic
chr14:45410181(-) A-I      intronic
chr14:45410578(-) A-I      intronic
chr14:45425397(-) A-I      intronic
chr14:45424744(-) A-I      intronic
chr14:45412639(-) A-I      intronic
chr14:45412656(-) A-I      intronic
chr14:45410251(-) A-I      intronic
chr14:45410289(-) A-I      intronic
chr14:45412777(-) A-I      intronic
chr14:45424776(-) A-I      intronic
chr14:45425453(-) A-I      intronic
chr14:45395992(-) A-I      3'UTR
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED KLHL28
chr14:45410289(-) A-I intron -    21960545
chr14:45395775(-) C-A exon 3'UTR    21725310

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase KLHL28
chr14:45397623-45397624(-) m6A 3'UTR       27773535
chr14:45397747-45397748(-) m6A 3'UTR       24981863//27773535
chr14:45397806-45397807(-) m6A 3'UTR       24981863//27773535
chr14:45397922-45397923(-) m6A 3'UTR       24981863//27773535//22608085
chr14:45397963-45397964(-) m6A 3'UTR       24981863//27773535//22608085
chr14:45397999-45398000(-) m6A 3'UTR       24981863//27773535//22608085
chr14:45398153-45398154(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr14:45398179-45398180(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr14:45398194-45398195(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr14:45398220-45398221(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr14:45400538-45400539(-) m6A CDS       24284625//24209618//27773535//22608085
chr14:45400545-45400546(-) m6A CDS       24284625//24209618//27773535//22608085
chr14:45400557-45400558(-) m6A CDS       24284625//24209618//27773535//22608085
chr14:45400568-45400569(-) m6A CDS       24284625//27773535//22608085
chr14:45400629-45400630(-) m6A CDS       24284625//24209618//24981863//27773535//27371828//22608085
chr14:45400717-45400718(-) m6A CDS       24284625//24981863//27773535//22608085
chr14:45403320-45403321(-) m6A CDS       24284625//24981863//27773535//22608085
chr14:45403472-45403473(-) m6A CDS       24284625//24209618//24981863//28052920//27773535//22575960//22608085
chr14:45403499-45403500(-) m6A CDS       24284625//24209618//24981863//28052920//27773535//22575960//22608085
chr14:45403561-45403562(-) m6A CDS       24284625//24209618//24981863//27773535//22608085
chr14:45403607-45403608(-) m6A CDS       24284625//24209618//24981863//27773535//22608085
chr14:45403671-45403672(-) m6A CDS       24284625//24209618//24981863//27773535//22608085
chr14:45403707-45403708(-) m6A CDS       24284625//24209618//24981863//27773535//22608085
chr14:45414252-45414253(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr14:45414317-45414318(-) m6A CDS       24284625//24209618//24981863//27773535//22608085
chr14:45414330-45414331(-) m6A CDS       24284625//24981863//27773535//22608085
chr14:45414336-45414337(-) m6A CDS       24284625//24981863//27773535//22608085
chr14:45414378-45414379(-) m6A CDS       24284625//24209618//24981863//27773535//22608085
chr14:45414423-45414424(-) m6A CDS       24284625//24209618//24981863//26404942//27773535//22608085
chr14:45414466-45414467(-) m6A CDS       24284625//24209618//24981863//26404942//27773535//22608085
chr14:45414542-45414543(-) m6A CDS       24284625//24209618//24981863//27773535//22575960//22608085
chr14:45414623-45414624(-) m6A CDS       24284625//24981863//27773535//22575960//22608085
chr14:45414695-45414696(-) m6A CDS       24284625//27773535//22608085
chr14:45414777-45414778(-) m6A CDS       24284625//24981863//27773535//22608085
chr14:45414793-45414794(-) m6A CDS       24284625//24981863//27773535//22608085
chr14:45414823-45414824(-) m6A CDS       24284625//24981863//27773535//27371828//22608085
chr14:45414842-45414843(-) m6A CDS       24284625//24209618//24981863//27773535//27371828//22608085
chr14:45414881-45414882(-) m6A CDS       24284625//24209618//24981863//27773535//27371828//22608085
chr14:45414913-45414914(-) m6A CDS       24284625//24209618//24981863//27773535//27371828//22608085
chr14:45414931-45414932(-) m6A CDS       24284625//24209618//24981863//27773535//27371828//22608085
chr14:45415032-45415033(-) m6A CDS       24284625//24209618//24981863//27773535//27371828//22608085
chr14:45415074-45415075(-) m6A CDS       24284625//24209618//24981863//27773535//27371828//22608085
chr14:45415126-45415127(-) m6A CDS       24284625//24209618//24981863//27773535//27371828//22608085
chr14:45431053-45431054(-) m6A 5'UTR//intron       24981863
chr14:45431351-45431352(-) m6A 5'UTR//intron       25456834//24981863//22608085
chr14:45431385-45431386(-) m6A 5'UTR//intron       24284625//25456834//24981863//22608085
chr14:45433157-45433158(-) m6A exon//intron       24284625//24209618//25456834//24981863//22575960//22608085
chr14:45447431-45447432(-) m6A 5'UTR//exon       24981863//22575960//22608085
chr14:45511327-45511328(-) m6A 5'UTR//exon       22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-616-3p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
KLHL28
Cytosol HCC cell line (HepG2)     -
Exosome Blood     -
Membrane HCC cell line (HepG2)     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HeLa-S3 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-616-3p
Interactor2: KLHL28

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region CDS
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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