Basic Information:

  VIRBase ID:  

HHID00067540

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-616-3p:  MIMAT0004805          TTC9:  NM_015351     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-616-3p	TTC9
miRBase Accession/Entrez ID	MIMAT0004805	23508
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	TTC9A

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-616-3p	rs374321661 chr12:57519192    C/T rs573303396 chr12:57519190    A/C rs573303396 chr12:57519190    A/G rs760442491 chr12:57519183    C/T rs763282175 chr12:57519193    C/T rs768469143 chr12:57519184    T/C rs776483081 chr12:57519185    G/A rs368928238 chr12:57519199    A/G rs377525107 chr12:57519198    A/C rs755336783 chr12:57519200    T/C

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	TTC9	chr14:71117802(+) A-I      intronic chr14:71116984(+) A-I      intronic chr14:71116980(+) A-I      intronic chr14:71117059(+) A-I      intronic chr14:71121229(+) A-I      intronic chr14:71121098(+) A-I      intronic chr14:71121076(+) A-I      intronic chr14:71121292(+) A-I      intronic chr14:71117959(+) A-I      intronic chr14:71122063(+) A-I      intronic chr14:71117933(+) A-I      intronic chr14:71116906(+) A-I      intronic chr14:71117815(+) A-I      intronic chr14:71122118(+) A-I      intronic chr14:71117921(+) A-I      intronic chr14:71117767(+) A-I      intronic chr14:71135711(+) A-I      intronic chr14:71117797(+) A-I      intronic chr14:71121217(+) A-I      intronic chr14:71121216(+) A-I      intronic chr14:71116914(+) A-I      intronic chr14:71116924(+) A-I      intronic chr14:71135464(+) A-I      intronic chr14:71135619(+) A-I      intronic chr14:71135663(+) A-I      intronic chr14:71117046(+) A-I      intronic chr14:71117025(+) A-I      intronic chr14:71116929(+) A-I      intronic chr14:71135448(+) A-I      intronic chr14:71111668(+) A-I      intronic chr14:71135447(+) A-I      intronic chr14:71117920(+) A-I      intronic chr14:71117927(+) A-I      intronic chr14:71137310(+) A-I      intronic chr14:71117884(+) A-I      intronic chr14:71121157(+) A-I      intronic chr14:71135518(+) A-I      intronic chr14:71116925(+) A-I      intronic chr14:71117934(+) A-I      intronic chr14:71116979(+) A-I      intronic chr14:71117798(+) A-I      intronic chr14:71135712(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	TTC9	chr14:71108705-71108706(+) m6A 5'UTR       24981863 chr14:71108883-71108884(+) m6A CDS       25456834 chr14:71109054-71109055(+) m6A CDS       24209618//25456834//24981863 chr14:71109144-71109145(+) m6A CDS       25456834//24981863//22608085 chr14:71134409-71134410(+) m6A CDS       - chr14:71134447-71134448(+) m6A CDS       24981863 chr14:71137832-71137833(+) m6A CDS       24284625//24209618//24981863 chr14:71137913-71137914(+) m6A 3'UTR       24284625//24209618//24981863 chr14:71138073-71138074(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr14:71138082-71138083(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr14:71138135-71138136(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr14:71138286-71138287(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr14:71138292-71138293(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr14:71138334-71138335(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr14:71138369-71138370(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr14:71138489-71138490(+) m6A 3'UTR       24284625//24209618//25456834//24981863 chr14:71138561-71138562(+) m6A 3'UTR       24284625//24209618//25456834//24981863 chr14:71138623-71138624(+) m6A 3'UTR       24284625//25456834//24981863 chr14:71138700-71138701(+) m6A 3'UTR       24284625//25456834//24981863 chr14:71138707-71138708(+) m6A 3'UTR       24284625//25456834//24981863 chr14:71138728-71138729(+) m6A 3'UTR       25456834//24981863 chr14:71140791-71140792(+) m6A 3'UTR       24284625//24981863 chr14:71140848-71140849(+) m6A 3'UTR       24284625//24981863 chr14:71140854-71140855(+) m6A 3'UTR       24284625//25456834//24981863 chr14:71140951-71140952(+) m6A 3'UTR       24284625//25456834//24981863 chr14:71140964-71140965(+) m6A 3'UTR       24284625//25456834//24981863 chr14:71140980-71140981(+) m6A 3'UTR       24284625//25456834//24981863 chr14:71141045-71141046(+) m6A 3'UTR       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-616-3p	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
	TTC9	Exosome Blood     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-616-3p
Interactor2: TTC9

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.