Detail Information

Basic Information:


  VIRBase ID:  

HHID00067248

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-582-3p:           SYVN1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-582-3p SYVN1
miRBase
Accession/Entrez ID		 MIMAT0004797 84447
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - DER3//HRD1

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-582-3p
rs1214574538 chr5:59703630    G/A
rs1241555697 chr5:59703637    T/C
rs753131546 chr5:59703642    C/G
rs753131546 chr5:59703642    C/T
rs767280360 chr5:59703651    A/T
rs1186977160 chr5:59703648    G/C
rs763354357 chr5:59703650    T/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR SYVN1
chr11:64901459(-) A-I      intronic
chr11:64896391(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase SYVN1
chr11:64889370-64889371(-) m6A intron       24284625//25456834//24981863//27773535//27371828//22575960
chr11:64889439-64889440(-) m6A intron       27371828
chr11:64889487-64889488(-) m6A intron       27371828
chr11:64889572-64889573(-) m6A exon       24284625//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr11:64889674-64889675(-) m6A exon       24284625//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr11:64889703-64889704(-) m6A exon       25456834//24981863//27773535//27371828//27773536
chr11:64889833-64889834(-) m6A exon       24284625//25456834//24981863//22608085
chr11:64889867-64889868(-) m6A exon       24284625//25456834//24981863//22608085
chr11:64894763-64894764(-) m6A 3'UTR//exon//intron       24284625//25456834//24981863//22608085
chr11:64895181-64895182(-) m6A 3'UTR//exon//intron       24284625
chr11:64895235-64895236(-) m6A 3'UTR//exon//intron       24284625//24209618//27773535//22575960
chr11:64895397-64895398(-) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr11:64895422-64895423(-) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr11:64895451-64895452(-) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr11:64895480-64895481(-) m6A 3'UTR//exon//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr11:64895800-64895801(-) m6A 3'UTR//exon//intron       24284625//27773535
chr11:64896145-64896146(-) m6A CDS//exon//intron       24284625//27773535
chr11:64897407-64897408(-) m6A exon//intron       24284625//27773535
chr11:64898263-64898264(-) m6A CDS//exon       27773535
chr11:64898419-64898420(-) m6A CDS//exon       27773535
chr11:64898468-64898469(-) m6A 3'UTR//CDS//exon       27773535
chr11:64898608-64898609(-) m6A 3'UTR//CDS//exon       27773535
chr11:64899794-64899795(-) m6A CDS//exon//intron       27773535
chr11:64899878-64899879(-) m6A exon//intron       27773535
chr11:64900396-64900397(-) m6A CDS//exon       27773535
chr11:64900405-64900406(-) m6A CDS//exon       27773535
chr11:64900508-64900509(-) m6A CDS//exon       27773535
chr11:64901799-64901800(-) m6A 5'UTR//intron       24981863
chr11:64901876-64901877(-) m6A 5'UTR//intron       24981863
chr11:64901882-64901883(-) m6A 5'UTR//intron       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-582-3p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
SYVN1
Chromatin K562 cells     -
Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HeLa-S3 cells|K562 cells     -

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-582-3p
D-Glucose 5793 Drug interaction    RC00007191
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-582-3p
Methyl (9R,10S,11S,12R,19R)-11-acetyloxy-12-ethyl-4-[(13S,15R,17S)-17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-8-formyl-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate 134755071       26617885

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-582-3p
Interactor2: SYVN1

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region CDS
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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