Detail Information

Basic Information:


  VIRBase ID:  

HHID00067240

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-582-3p:           CCL3:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-582-3p CCL3
miRBase
Accession/Entrez ID		 MIMAT0004797 6348
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - G0S19-1//LD78ALPHA//MIP-1-alpha//MIP1A//SCYA3

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-582-3p
rs1214574538 chr5:59703630    G/A
rs1241555697 chr5:59703637    T/C
rs753131546 chr5:59703642    C/G
rs753131546 chr5:59703642    C/T
rs767280360 chr5:59703651    A/T
rs1186977160 chr5:59703648    G/C
rs763354357 chr5:59703650    T/C

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase CCL3
chr17:34416799-34416800(-) m6A exon//intron       26404942
chr17:34416836-34416837(-) m6A exon//intron       26404942
chr17:34416843-34416844(-) m6A exon//intron       26404942
chr17:34417469-34417470(-) m6A 5'UTR//exon       26404942
chr17:34417482-34417483(-) m6A 5'UTR//exon       26404942
chr17:34417493-34417494(-) m6A exon       26404942

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-582-3p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
CCL3
Exosome Blood     -

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-582-3p
D-Glucose 5793 Drug interaction    RC00007191
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-582-3p
Methyl (9R,10S,11S,12R,19R)-11-acetyloxy-12-ethyl-4-[(13S,15R,17S)-17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-8-formyl-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate 134755071       26617885

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-582-3p
Interactor2: CCL3

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region CDS
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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