Detail Information

Basic Information:


  VIRBase ID:  

HHID00066914

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-513a-3p:           CHUK:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-513a-3p CHUK
miRBase
Accession/Entrez ID		 MIMAT0004777 1147
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - IKBKA//IKK-alpha//IKK1//IKKA//NFKBIKA//TCF16

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-513a-3p
rs1193611712 chrX:147213509    A/T
rs1476837748 chrX:147213505    A/G
rs1557097520 chrX:147213503    T/A
rs781863468 chrX:147213501    T/TCACCTTCAC
rs782461607 chrX:147213499    C/G
rs782461607 chrX:147213499    C/T
rs782612905 chrX:147213506    G/C
rs1376206275 chrX:147225882    A/C
rs1557100144 chrX:147225860    C/T
rs1557100149 chrX:147225872    G/A
rs782066339 chrX:147225868    G/C
rs781849357 chrX:147213515    A/C
rs782140998 chrX:147213516    AT/A
rs782514669 chrX:147213517    T/A
rs782794884 chrX:147213518    TTA/T
rs1240793492 chrX:147225877    A/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR CHUK
chr10:101971736(-) A-I      intronic
chr10:101983246(-) A-I      intronic
chr10:101981559(-) A-I      intronic
chr10:101968034(-) A-I      intronic
chr10:101973070(-) A-I      intronic
chr10:101983283(-) A-I      intronic
chr10:101983208(-) A-I      intronic
chr10:101971816(-) A-I      intronic
chr10:101981583(-) A-I      intronic
chr10:101981688(-) A-I      intronic
chr10:101984771(-) A-I      intronic
chr10:101981594(-) A-I      intronic
chr10:101983247(-) A-I      intronic
chr10:101957550(-) A-I      intronic
chr10:101981588(-) A-I      intronic
chr10:101968043(-) A-I      intronic
chr10:101968481(-) A-I      intronic
chr10:101972994(-) A-I      intronic
chr10:101977510(-) A-I      intronic
chr10:101971807(-) A-I      intronic
chr10:101968041(-) A-I      intronic
chr10:101967925(-) A-I      intronic
chr10:101971732(-) A-I      intronic
chr10:101968535(-) A-I      intronic
chr10:101968010(-) A-I      intronic
chr10:101962678(-) A-I      intronic
chr10:101973093(-) A-I      intronic
chr10:101968302(-) A-I      intronic
chr10:101967961(-) A-I      intronic
chr10:101968410(-) A-I      intronic
chr10:101968394(-) A-I      intronic
chr10:101973072(-) A-I      intronic
chr10:101988351(-) A-I      intronic
chr10:101973521(-) A-I      intronic
chr10:101949650(-) A-I      intronic
chr10:101973035(-) A-I      intronic
chr10:101968480(-) A-I      intronic
chr10:101968135(-) A-I      intronic
chr10:101965515(-) A-I      intronic
chr10:101971737(-) A-I      intronic
chr10:101988378(-) A-I      intronic
chr10:101973458(-) A-I      intronic
chr10:101973119(-) A-I      intronic
chr10:101967966(-) A-I      intronic
chr10:101967892(-) A-I      intronic
chr10:101973472(-) A-I      intronic
chr10:101973482(-) A-I      intronic
chr10:101968378(-) A-I      intronic
chr10:101973417(-) A-I      intronic
chr10:101956233(-) A-I      intronic
chr10:101968114(-) A-I      intronic
chr10:101973066(-) A-I      intronic
chr10:101988404(-) A-I      intronic
chr10:101988166(-) A-I      intronic
chr10:101968136(-) A-I      intronic
chr10:101971804(-) A-I      intronic
chr10:101988167(-) A-I      intronic
chr10:101981533(-) A-I      intronic
chr10:101976384(-) A-I      intronic
chr10:101971810(-) A-I      intronic
chr10:101957562(-) A-I      intronic
chr10:101973411(-) A-I      intronic
chr10:101968393(-) A-I      intronic
chr10:101973012(-) A-I      intronic
chr10:101968118(-) A-I      intronic
chr10:101973180(-) A-I      intronic
chr10:101968028(-) A-I      intronic
chr10:101972596(-) A-I      intronic
chr10:101973346(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED CHUK
chr10:101968481(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase CHUK
chr10:101985771-101985772(-) m6A CDS       24209618//27371828//27773536
chr10:101989315-101989316(-) m6A 5'UTR       24981863//27371828//27773536
chr10:101989326-101989327(-) m6A 5'UTR       24981863//27371828//27773536
chr10:101989338-101989339(-) m6A 5'UTR       24981863//27371828//27773536
chr10:101989368-101989369(-) m6A 5'UTR       24981863//27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-513a-3p
Exosome B cell line (Raji)|Jurkat-derived T cell line (J77cl20)     21505438
Exosome Ovarian follicular fluid     22116803
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
CHUK
Chromatin K562 cells     -
Cytosol HCC cell line (HepG2)     -
Exosome Blood     -
Membrane HCC cell line (HepG2)     -
Ribosome Colon cancer cells     24393600

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-513a-3p
Paclitaxel 36314 Drug interaction    RC00007177
cis-Diaminedichloroplatinum 2767 Drug interaction    RC00007176
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-513a-3p
Cisplatin 5702198       22749944
Doxorubicin 31703       25698578

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-513a-3p
Interactor2: CHUK

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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