Basic Information:

  VIRBase ID:  

HHID00066869

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-501-3p:  MIMAT0004774          ZC3H12C:  NM_033390     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-501-3p	ZC3H12C
miRBase Accession/Entrez ID	MIMAT0004774	85463
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	MCPIP3

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-501-3p	rs112489955 chrX:50009781    G/A rs112489955 chrX:50009781    G/T rs1557182212 chrX:50009793    T/C rs376696825 chrX:50009787    G/A rs376696825 chrX:50009787    G/T rs781947379 chrX:50009780    C/T rs782814071 chrX:50009784    C/T rs149912461 chrX:50009773    A/G rs1557182197 chrX:50009774    T/C rs367629841 chrX:50009778    C/T rs782056456 chrX:50009775    G/A

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	ZC3H12C	chr11:110032818(+) A-I      intronic chr11:110037435(+) A-I      3'UTR chr11:110041539(+) A-I      3'UTR chr11:110032826(+) A-I      intronic chr11:110032851(+) A-I      intronic chr11:110032869(+) A-I      intronic chr11:110032755(+) A-I      intronic chr11:110024096(+) A-I      intronic chr11:110009504(+) A-I      intronic chr11:109973463(+) A-I      intronic chr11:109972377(+) A-I      intronic chr11:109972372(+) A-I      intronic chr11:109972353(+) A-I      intronic chr11:109972352(+) A-I      intronic chr11:109972342(+) A-I      intronic chr11:109972292(+) A-I      intronic chr11:110032811(+) A-I      intronic chr11:110010848(+) A-I      intronic chr11:110029070(+) A-I      intronic chr11:110027720(+) A-I      intronic chr11:110028261(+) A-I      intronic chr11:110031778(+) A-I      intronic chr11:109974814(+) A-I      intronic chr11:110027705(+) A-I      intronic chr11:110031832(+) A-I      intronic chr11:109974430(+) A-I      intronic chr11:110032738(+) A-I      intronic chr11:110008717(+) A-I      intronic chr11:110029085(+) A-I      intronic chr11:110028346(+) A-I      intronic chr11:110032813(+) A-I      intronic chr11:109970417(+) A-I      intronic chr11:110029195(+) A-I      intronic chr11:109986200(+) A-I      intronic chr11:110028290(+) A-I      intronic chr11:109986289(+) A-I      intronic chr11:110032748(+) A-I      intronic chr11:110031843(+) A-I      intronic chr11:110032722(+) A-I      intronic chr11:110032680(+) A-I      intronic chr11:110032672(+) A-I      intronic chr11:110032669(+) A-I      intronic chr11:110032657(+) A-I      intronic chr11:110031803(+) A-I      intronic chr11:110031749(+) A-I      intronic chr11:110031665(+) A-I      intronic chr11:110029083(+) A-I      intronic chr11:110029002(+) A-I      intronic chr11:110028390(+) A-I      intronic chr11:110028361(+) A-I      intronic chr11:110028265(+) A-I      intronic chr11:110028224(+) A-I      intronic chr11:110028179(+) A-I      intronic chr11:110027797(+) A-I      intronic chr11:110027793(+) A-I      intronic chr11:110027765(+) A-I      intronic chr11:110027752(+) A-I      intronic chr11:110027742(+) A-I      intronic chr11:110027739(+) A-I      intronic chr11:110010825(+) A-I      intronic chr11:110008769(+) A-I      intronic chr11:110008753(+) A-I      intronic chr11:110008745(+) A-I      intronic chr11:110008715(+) A-I      intronic chr11:109996277(+) A-I      intronic chr11:109996226(+) A-I      intronic chr11:109996163(+) A-I      intronic chr11:109996146(+) A-I      intronic chr11:109996145(+) A-I      intronic chr11:109996097(+) A-I      intronic chr11:110028260(+) A-I      intronic chr11:109989506(+) A-I      intronic chr11:109989505(+) A-I      intronic chr11:109989424(+) A-I      intronic chr11:109989423(+) A-I      intronic chr11:109989388(+) A-I      intronic chr11:109989375(+) A-I      intronic chr11:109998500(+) A-I      intronic chr11:109986737(+) A-I      intronic chr11:109986695(+) A-I      intronic chr11:109986685(+) A-I      intronic chr11:109986674(+) A-I      intronic chr11:109986670(+) A-I      intronic chr11:109986668(+) A-I      intronic chr11:109986544(+) A-I      intronic chr11:109986230(+) A-I      intronic chr11:109972516(+) A-I      intronic chr11:109972509(+) A-I      intronic chr11:109972477(+) A-I      intronic chr11:109972412(+) A-I      intronic chr11:109972402(+) A-I      intronic chr11:109972390(+) A-I      intronic chr11:109972438(+) A-I      intronic chr11:109970427(+) A-I      intronic chr11:109978161(+) A-I      intronic chr11:110028318(+) A-I      intronic chr11:109970387(+) A-I      intronic chr11:110028350(+) A-I      intronic chr11:110028239(+) A-I      intronic chr11:110028302(+) A-I      intronic chr11:110028246(+) A-I      intronic chr11:109989443(+) A-I      intronic chr11:110032601(+) A-I      intronic chr11:109970459(+) A-I      intronic chr11:110009363(+) A-I      intronic chr11:109986237(+) A-I      intronic chr11:110032600(+) A-I      intronic chr11:109996127(+) A-I      intronic chr11:110024998(+) A-I      intronic chr11:109996278(+) A-I      intronic chr11:110031691(+) A-I      intronic chr11:109998455(+) A-I      intronic chr11:110028286(+) A-I      intronic chr11:109996223(+) A-I      intronic chr11:109986128(+) A-I      intronic chr11:109986131(+) A-I      intronic chr11:109986194(+) A-I      intronic chr11:110027728(+) A-I      intronic chr11:110027694(+) A-I      intronic chr11:109972373(+) A-I      intronic chr11:110028353(+) A-I      intronic chr11:109978721(+) A-I      intronic chr11:110028375(+) A-I      intronic chr11:110009493(+) A-I      intronic chr11:110006050(+) A-I      intronic chr11:110031804(+) A-I      intronic chr11:109989260(+) A-I      intronic chr11:109982947(+) A-I      intronic chr11:109986619(+) A-I      intronic chr11:110010811(+) A-I      intronic chr11:109974946(+) A-I      intronic chr11:110031701(+) A-I      intronic chr11:110028344(+) A-I      intronic chr11:110031631(+) A-I      intronic chr11:109970384(+) A-I      intronic chr11:110025893(+) A-I      intronic chr11:109972414(+) A-I      intronic chr11:109972489(+) A-I      intronic chr11:109989307(+) A-I      intronic chr11:110028330(+) A-I      intronic chr11:110010851(+) A-I      intronic chr11:109998405(+) A-I      intronic chr11:110028264(+) A-I      intronic chr11:109970480(+) A-I      intronic chr11:110031662(+) A-I      intronic chr11:110009506(+) A-I      intronic chr11:109974395(+) A-I      intronic chr11:110028234(+) A-I      intronic chr11:109978773(+) A-I      intronic chr11:110028345(+) A-I      intronic chr11:110010856(+) A-I      intronic chr11:110005937(+) A-I      intronic chr11:109986145(+) A-I      intronic chr11:110028335(+) A-I      intronic chr11:110027651(+) A-I      intronic chr11:109996217(+) A-I      intronic chr11:110031766(+) A-I      intronic chr11:110028370(+) A-I      intronic chr11:109974354(+) A-I      intronic chr11:110009505(+) A-I      intronic chr11:110029192(+) A-I      intronic chr11:110032670(+) A-I      intronic chr11:110031752(+) A-I      intronic chr11:110028178(+) A-I      intronic chr11:109970463(+) A-I      intronic chr11:110006170(+) A-I      intronic chr11:110028278(+) A-I      intronic chr11:110028300(+) A-I      intronic chr11:110025953(+) A-I      intronic chr11:110031831(+) A-I      intronic chr11:110028399(+) A-I      intronic chr11:110023936(+) A-I      intronic chr11:110031626(+) A-I      intronic chr11:109976739(+) A-I      intronic chr11:109970385(+) A-I      intronic chr11:110008730(+) A-I      intronic chr11:110029150(+) A-I      intronic chr11:109996317(+) A-I      intronic chr11:110032712(+) A-I      intronic chr11:109986603(+) A-I      intronic chr11:109986107(+) A-I      intronic chr11:109986290(+) A-I      intronic chr11:110027757(+) A-I      intronic chr11:110032739(+) A-I      intronic chr11:110027733(+) A-I      intronic chr11:109998364(+) A-I      intronic chr11:110032850(+) A-I      intronic chr11:110031606(+) A-I      intronic chr11:110028400(+) A-I      intronic chr11:110031698(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	ZC3H12C	chr11:110028345(+) A-I intron -    22327324 chr11:109986128(+) A-G intron -    22484847 chr11:109986131(+) A-G intron -    22484847 chr11:109986145(+) A-G intron -    22484847 chr11:109986290(+) A-G intron -    22484847 chr11:110010811(+) A-G intron -    22484847 chr11:110027733(+) A-G intron -    22484847 chr11:110028261(+) A-G intron -    22484847 chr11:110028345(+) A-G intron -    22484847 chr11:110028346(+) A-G intron -    22484847 chr11:110029195(+) A-G intron -    22484847 chr11:110031606(+) A-G intron -    22484847 chr11:110032748(+) A-G intron -    22484847 chr11:110032813(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	ZC3H12C	chr11:110007559-110007560(+) m6A CDS       22608085 chr11:110007643-110007644(+) m6A CDS       24284625//24209618//24981863//22608085 chr11:110007668-110007669(+) m6A CDS       24284625//24209618//24981863//22575960//22608085 chr11:110007711-110007712(+) m6A CDS       24284625//24209618//24981863//22575960//22608085 chr11:110007719-110007720(+) m6A CDS       24284625//24209618//24981863//22575960//22608085 chr11:110007781-110007782(+) m6A CDS       24284625//24981863//22575960//22608085 chr11:110007788-110007789(+) m6A CDS       24284625//24981863//22575960//22608085 chr11:110007804-110007805(+) m6A CDS       24284625//24981863//22575960//22608085 chr11:110007827-110007828(+) m6A CDS       24284625//24981863//22575960//22608085 chr11:110007855-110007856(+) m6A CDS       24284625//24981863//22575960//22608085 chr11:110007860-110007861(+) m6A CDS       24284625//24981863//22575960//22608085 chr11:110007896-110007897(+) m6A CDS       24284625//24981863//22575960//22608085 chr11:110007916-110007917(+) m6A CDS       24284625//24981863//22575960//22608085 chr11:110007959-110007960(+) m6A CDS       24284625//24981863//22575960//22608085 chr11:110007968-110007969(+) m6A CDS       24284625//24981863//22608085 chr11:110008029-110008030(+) m6A CDS       24209618//24981863//22608085 chr11:110008103-110008104(+) m6A CDS       24209618//24981863//22608085 chr11:110023651-110023652(+) m6A CDS       24209618 chr11:110035084-110035085(+) m6A CDS       24981863 chr11:110035147-110035148(+) m6A CDS       24284625//24981863//22608085 chr11:110035181-110035182(+) m6A CDS       24284625//24981863//22608085 chr11:110035198-110035199(+) m6A CDS       24284625//24981863//22608085 chr11:110035298-110035299(+) m6A CDS       24284625//24981863//22608085 chr11:110035314-110035315(+) m6A CDS       24284625//24981863//22608085 chr11:110035341-110035342(+) m6A CDS       24284625//24981863//22608085 chr11:110035352-110035353(+) m6A CDS       24284625//24981863//22608085 chr11:110035402-110035403(+) m6A CDS       24284625//24981863//22608085 chr11:110035471-110035472(+) m6A CDS       24284625//24981863//22608085 chr11:110035480-110035481(+) m6A CDS       24284625//24981863//22608085 chr11:110035537-110035538(+) m6A CDS       24284625//24981863//22608085 chr11:110035650-110035651(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr11:110035891-110035892(+) m6A CDS       24284625//24981863//22608085 chr11:110036055-110036056(+) m6A CDS       24284625//24209618//24981863//22575960//22608085 chr11:110036183-110036184(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr11:110036316-110036317(+) m6A CDS       24284625//24209618//24981863//22608085 chr11:110036658-110036659(+) m6A 3'UTR       24981863 chr11:110036867-110036868(+) m6A 3'UTR       24981863//22608085 chr11:110036879-110036880(+) m6A 3'UTR       24981863//22608085 chr11:110036888-110036889(+) m6A 3'UTR       24981863//22608085 chr11:110036916-110036917(+) m6A 3'UTR       24981863//22608085 chr11:110040485-110040486(+) m6A 3'UTR       22608085 chr11:110042092-110042093(+) m6A 3'UTR       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-501-3p	Exosome Primary dendritic cells     21505438 Exosome Plasma     23663360 Exosome Human mast cell line (HMC-1)     24009880 Exosome Blood     - Microvesicle Seminal plasma     23539611 Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     - Mitochondrion Myotube     27396686 Mitochondrion Skeletal muscle cells     27563705 Mitochondrion Skeletal muscle myoblasts     21637849 Mitochondrion Cell line (HEK-293|HeLa)     22984580
	ZC3H12C	Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Membrane K562 cells     - Nucleoplasm K562 cells     - Nucleus K562 cells     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID	PMID
NoncoRNA	hsa-miR-501-3p	Cisplatin 5702198       30221699

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-501-3p
Interactor2: ZC3H12C

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.