Detail Information

Basic Information:


  VIRBase ID:  

HHID00066837

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-500a-5p:           TM9SF1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-500a-5p TM9SF1
miRBase
Accession/Entrez ID		 MIMAT0004773 10548
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - HMP70//MP70

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-500a-5p
rs1221490724 chrX:50008465    A/G
rs1557181893 chrX:50008443    T/G
rs1557181895 chrX:50008452    C/G
rs1557181897 chrX:50008453    T/A
rs1557181900 chrX:50008458    G/A
rs1557181900 chrX:50008458    G/C
rs1557181904 chrX:50008463    A/T
rs369176381 chrX:50008450    T/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR TM9SF1
chr14:24662646(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase TM9SF1
chr14:24658566-24658567(-) m6A 3'UTR       24284625//24981863//22608085
chr14:24658604-24658605(-) m6A 3'UTR       24284625//24981863//22608085
chr14:24658624-24658625(-) m6A 3'UTR//CDS       24284625//24981863//22608085
chr14:24659430-24659431(-) m6A 3'UTR//intron       24981863
chr14:24659666-24659667(-) m6A 3'UTR//CDS//intron       24284625//27773535
chr14:24659705-24659706(-) m6A CDS//intron       24284625//27773535
chr14:24661005-24661006(-) m6A exon//intron       24284625
chr14:24661017-24661018(-) m6A exon//intron       24284625
chr14:24661040-24661041(-) m6A exon//intron       24284625//27773535
chr14:24661210-24661211(-) m6A exon//intron       27773535
chr14:24661223-24661224(-) m6A exon//intron       24284625//27773535
chr14:24661233-24661234(-) m6A exon//intron       24284625//27773535
chr14:24661271-24661272(-) m6A exon//intron       24284625//24981863//27773535//22608085
chr14:24661325-24661326(-) m6A exon//intron       24284625//24981863//27773535
chr14:24661340-24661341(-) m6A exon//intron       24284625//27773535
chr14:24661369-24661370(-) m6A exon//intron       24284625//27773535
chr14:24661405-24661406(-) m6A CDS//exon//intron       24284625
chr14:24662000-24662001(-) m6A CDS//exon//intron       24284625//24209618//24981863//27773535//22575960//22608085
chr14:24662129-24662130(-) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr14:24662189-24662190(-) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr14:24662305-24662306(-) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr14:24662329-24662330(-) m6A CDS//intron       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr14:24662339-24662340(-) m6A CDS//intron       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr14:24662346-24662347(-) m6A CDS//intron       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr14:24662445-24662446(-) m6A CDS//intron       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085
chr14:24663968-24663969(-) m6A 5'UTR//CDS//intron       24284625//24209618//26404942//27773535//22575960//22608085
chr14:24664053-24664054(-) m6A CDS//intron       24284625//24209618//26404942//27773535//22575960
chr14:24664075-24664076(-) m6A CDS//intron       24284625//24209618//26404942//27773535//22575960
chr14:24664208-24664209(-) m6A CDS//intron       24284625//27773535//27371828
chr14:24664245-24664246(-) m6A 5'UTR//intron       27773535//27371828
chr14:24664317-24664318(-) m6A 5'UTR//intron       27773536
chr14:24664506-24664507(-) m6A 5'UTR//intron       27773536
chr14:24664520-24664521(-) m6A 5'UTR//intron       27773536
chr14:24664544-24664545(-) m6A 5'UTR//intron       24981863//27773536
chr14:24664626-24664627(-) m6A 5'UTR//intron       24981863//26404942//27773536
chr14:24664856-24664857(-) m6A 5'UTR       27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-500a-5p
Exosome Primary dendritic cells     21505438
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Seminal plasma     23539611
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
Mitochondrion Skeletal muscle myoblasts     21637849
Nucleus Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059
TM9SF1
Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleus HCC cell line (HepG2)|K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-500a-5p
Interactor2: TM9SF1

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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