Detail Information

Basic Information:


  VIRBase ID:  

HHID00066834

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-500a-5p:           ZFAND5:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-500a-5p ZFAND5
miRBase
Accession/Entrez ID		 MIMAT0004773 7763
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - ZA20D2//ZFAND5A//ZNF216

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-500a-5p
rs1221490724 chrX:50008465    A/G
rs1557181893 chrX:50008443    T/G
rs1557181895 chrX:50008452    C/G
rs1557181897 chrX:50008453    T/A
rs1557181900 chrX:50008458    G/A
rs1557181900 chrX:50008458    G/C
rs1557181904 chrX:50008463    A/T
rs369176381 chrX:50008450    T/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR ZFAND5
chr9:74968543(-) A-I      3'UTR
chr9:74967193(-) A-I      3'UTR
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED ZFAND5
chr9:74971252(-) A-I intron -    19478186
chr9:74966576(-) A-I exon 3'UTR    22327324

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase ZFAND5
chr9:74969373-74969374(-) m6A 3'UTR//exon       27773535
chr9:74969818-74969819(-) m6A 3'UTR//exon       24284625//24209618//24981863//26404942//27773535//22575960//22608085
chr9:74969883-74969884(-) m6A 3'UTR//exon       24284625//24209618//24981863//26404942//27773535//22575960//22608085
chr9:74969948-74969949(-) m6A 3'UTR//exon       24284625//24209618//24981863//26404942//27773535//22575960//22608085
chr9:74970094-74970095(-) m6A 3'UTR//exon       24284625//24209618//24981863//26404942//27773535//22575960//22608085
chr9:74970133-74970134(-) m6A 3'UTR//exon       24284625//24209618//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr9:74970239-74970240(-) m6A 3'UTR//exon       24284625//24209618//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr9:74970255-74970256(-) m6A 3'UTR//exon       24284625//24209618//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr9:74970263-74970264(-) m6A 3'UTR//exon       24284625//24209618//24981863//26404942//27773535//22575960//22608085
chr9:74970281-74970282(-) m6A 3'UTR//exon       24284625//24209618//24981863//26404942//27773535//22575960//22608085
chr9:74970342-74970343(-) m6A 3'UTR//exon       24284625//24209618//24981863//26404942//27773535//22575960//22608085
chr9:74970359-74970360(-) m6A 3'UTR//exon       24284625//24209618//24981863//26404942//27773535//22608085
chr9:74970427-74970428(-) m6A 3'UTR//exon       24284625//24209618//24981863//26404942//27773535//22608085
chr9:74970455-74970456(-) m6A 3'UTR//exon       24284625//24209618//24981863//26404942//27773535//22608085
chr9:74970576-74970577(-) m6A 3'UTR//exon       24284625//24981863//26404942//27773535
chr9:74970601-74970602(-) m6A 3'UTR//exon       24981863//26404942//27773535
chr9:74970618-74970619(-) m6A 3'UTR//exon       24981863//26404942//27773535
chr9:74970811-74970812(-) m6A 3'UTR//exon       24981863//27773535//22608085
chr9:74970843-74970844(-) m6A 3'UTR//exon       24981863//27773535//22608085
chr9:74970849-74970850(-) m6A 3'UTR//exon       24981863//27773535//22608085
chr9:74974351-74974352(-) m6A CDS//exon       -
chr9:74974371-74974372(-) m6A CDS//exon       -
chr9:74975067-74975068(-) m6A CDS//exon       -
chr9:74975079-74975080(-) m6A CDS//exon       -
chr9:74975444-74975445(-) m6A exon//intron       24981863//27371828
chr9:74975486-74975487(-) m6A exon//intron       24981863//27371828
chr9:74975499-74975500(-) m6A exon//intron       24981863//27371828
chr9:74975507-74975508(-) m6A exon//intron       24981863
chr9:74975521-74975522(-) m6A exon//intron       24981863
chr9:74975672-74975673(-) m6A CDS//exon       -
chr9:74975681-74975682(-) m6A CDS//exon       -
chr9:74978404-74978405(-) m6A 5'UTR//exon//intron       -
chr9:74978410-74978411(-) m6A 5'UTR//exon//intron       -
chr9:74978417-74978418(-) m6A 5'UTR//exon//intron       -
chr9:74978447-74978448(-) m6A 5'UTR//exon//intron       -
chr9:74978468-74978469(-) m6A 5'UTR//exon//intron       -
chr9:74979414-74979415(-) m6A 5'UTR//CDS//intron       27773536
chr9:74979542-74979543(-) m6A 5'UTR//intron       24209618//27773536
chr9:74979620-74979621(-) m6A 5'UTR//exon       24209618//27773536
chr9:74979640-74979641(-) m6A 5'UTR//exon       24209618//27773536
chr9:74979775-74979776(-) m6A 5'UTR//exon       24284625//27371828//27773536//22575960
chr9:74979785-74979786(-) m6A 5'UTR//exon       24284625//27371828//27773536//22575960

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-500a-5p
Exosome Primary dendritic cells     21505438
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Seminal plasma     23539611
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
Mitochondrion Skeletal muscle myoblasts     21637849
Nucleus Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059
ZFAND5
Chromatin K562 cells     -
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Cytoplasm Nasopharyngeal carcinoma cells     20498841
Exosome Blood     -
Nucleus Nasopharyngeal carcinoma cells     20498841
Nucleus Nasopharyngeal carcinoma cells     20498841
Nucleus Nasopharyngeal carcinoma cells     20498841
Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-500a-5p
Interactor2: ZFAND5

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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