Basic Information:

  VIRBase ID:  

HHID00066785

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-146b-3p:  MIMAT0004766          MARCHF9:  NM_138396     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-146b-3p	MARCHF9
miRBase Accession/Entrez ID	MIMAT0004766	92979
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	MARCH-IX//MARCH9//RNF179

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-146b-3p	rs1367942461 chr10:102436557    G/A rs1467375133 chr10:102436569    C/A rs766852690 chr10:102436575    TGGTGCCC/T rs768018523 chr10:102436577    G/C rs1425832655 chr10:102436558    C/T rs944616447 chr10:102436564    G/A

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-146b-3p	Exosome Pulmonary epithelial cell line (BEAS-2B)     31520698 Exosome Plasma     23663360 Exosome Mast cells     - Microvesicle Fibroblasts|Mesenchymal stem cells     -
	MARCHF9	Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Nucleus K562 cells     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID
RNAactDrug	hsa-miR-146b-3p	l-685,458       5479543

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-146b-3p
Interactor2: MARCHF9

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.