Detail Information

Basic Information:


  VIRBase ID:  

HHID00066776

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-146b-3p:           BLCAP:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-146b-3p BLCAP
miRBase
Accession/Entrez ID		 MIMAT0004766 10904
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - BC10

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-146b-3p
rs1367942461 chr10:102436557    G/A
rs1467375133 chr10:102436569    C/A
rs766852690 chr10:102436575    TGGTGCCC/T
rs768018523 chr10:102436577    G/C
rs1425832655 chr10:102436558    C/T
rs944616447 chr10:102436564    G/A

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR BLCAP
chr20:36139602(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED BLCAP
chr20:36147533(-) A-I exon CDS    19478186
chr20:36147534(-) A-I exon CDS    15797904
chr20:36147563(-) A-I exon CDS    15797904   //22327324
chr20:36147572(-) A-I exon CDS    15797904   //21960545
chr20:36147581(-) A-I exon 5'UTR    15797904
chr20:36147583(-) A-I exon 5'UTR    15797904
chr20:36147572(-) A-G exon CDS    21725310
chr20:36147533(-) A-G exon CDS    22484847
chr20:36147563(-) A-G exon CDS    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase BLCAP
chr20:36121202-36121203(-) m6A exon       -
chr20:36121212-36121213(-) m6A exon       -
chr20:36130420-36130421(-) m6A exon//intron       -
chr20:36130521-36130522(-) m6A exon//intron       -
chr20:36130559-36130560(-) m6A exon//intron       -
chr20:36130623-36130624(-) m6A exon//intron       -
chr20:36131571-36131572(-) m1A exon//intron       26863196
chr20:36137626-36137627(-) m6A exon//intron       24981863//27773535//22608085
chr20:36145823-36145824(-) m6A 3'UTR//intron       24981863//27773535//22608085
chr20:36145895-36145896(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr20:36145925-36145926(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr20:36145953-36145954(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr20:36145958-36145959(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr20:36146065-36146066(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr20:36146125-36146126(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085
chr20:36146154-36146155(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085
chr20:36146215-36146216(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr20:36146220-36146221(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr20:36146237-36146238(-) m6A 3'UTR//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr20:36146727-36146728(-) m6A 3'UTR//intron       27773535
chr20:36146733-36146734(-) m6A 3'UTR//intron       27773535
chr20:36146829-36146830(-) m6A 3'UTR//intron       27773535
chr20:36148651-36148652(-) m6A 5'UTR//intron       24981863//27773536//22575960
chr20:36148701-36148702(-) m6A 5'UTR//intron       24981863//27773536
chr20:36149810-36149811(-) m6A 5'UTR//intron       24981863
chr20:36149820-36149821(-) m6A 5'UTR//intron       24981863
chr20:36149837-36149838(-) m6A 5'UTR//intron       24981863
chr20:36156301-36156302(-) m6A 5'UTR       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-146b-3p
Exosome Pulmonary epithelial cell line (BEAS-2B)     31520698
Exosome Plasma     23663360
Exosome Mast cells     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
BLCAP
Chromatin K562 cells     -
Exosome Blood     -
Membrane HCC cell line (HepG2)     -
Ribosome Colon cancer cells     24393600

Related Drug Information:


Resource Symbol Drug Name PubChem ID
RNAactDrug hsa-miR-146b-3p
l-685,458       5479543

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-146b-3p
Interactor2: BLCAP

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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