Detail Information

Basic Information:


  VIRBase ID:  

HHID00066325

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-374a-3p:           LYSMD3:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-374a-3p LYSMD3
miRBase
Accession/Entrez ID		 MIMAT0004688 116068
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - -

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-374a-3p
rs766292977 chrX:74287300    C/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR LYSMD3
chr5:89820968(-) A-I      NonSyn:Lys->Glu
chr5:89820969(-) A-I      Syn:Gly->Gly
chr5:89820966(-) A-I      Syn:Lys->Lys
chr5:89820681(-) A-I      intronic
chr5:89820682(-) A-I      intronic
chr5:89820477(-) A-I      intronic
chr5:89816480(-) A-I      intronic
chr5:89816624(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase LYSMD3
chr5:89814162-89814163(-) m6A 3'UTR       27773535
chr5:89814239-89814240(-) m6A 3'UTR       27773535
chr5:89814640-89814641(-) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22608085
chr5:89814683-89814684(-) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22608085
chr5:89814792-89814793(-) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr5:89814898-89814899(-) m6A 3'UTR//CDS//intron       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr5:89814918-89814919(-) m6A 3'UTR//CDS//intron       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr5:89814936-89814937(-) m6A 3'UTR//CDS//intron       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr5:89814951-89814952(-) m6A 3'UTR//CDS//intron       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr5:89814965-89814966(-) m6A 3'UTR//CDS//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr5:89815014-89815015(-) m6A 3'UTR//CDS//intron       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr5:89815029-89815030(-) m6A 3'UTR//CDS//intron       24284625//24209618//24981863//28052920//27773535//27371828//22575960//22608085
chr5:89815049-89815050(-) m6A 3'UTR//CDS//intron       24284625//24209618//24981863//28052920//27773535//27371828//22575960//22608085
chr5:89815056-89815057(-) m6A 3'UTR//CDS//intron       24284625//24209618//24981863//28052920//27773535//27371828//22575960//22608085
chr5:89815062-89815063(-) m6A 3'UTR//CDS//intron       24284625//24209618//24981863//28052920//27773535//27371828//22575960//22608085
chr5:89815136-89815137(-) m6A CDS//intron       24284625//24209618//24981863//27773535//27371828//22608085
chr5:89815175-89815176(-) m6A CDS//intron       24284625//24981863//27773535//27371828//22608085
chr5:89815198-89815199(-) m6A CDS//intron       24284625//24981863//27773535//22608085
chr5:89815257-89815258(-) m6A 3'UTR//CDS//intron       24284625//27773535//22608085
chr5:89816208-89816209(-) m6A 3'UTR//intron       27773535//22608085
chr5:89816233-89816234(-) m6A 3'UTR//intron       27773535//22608085
chr5:89820932-89820933(-) m6A CDS       24284625//24981863//27773535//22608085
chr5:89820983-89820984(-) m6A CDS       24981863//27773535//27371828//22608085
chr5:89821020-89821021(-) m6A CDS       24981863//27773535//27371828//22608085
chr5:89822761-89822762(-) m6A 5'UTR//intron       27773535//27371828
chr5:89822784-89822785(-) m6A 5'UTR//intron       27773535//27371828
chr5:89825267-89825268(-) m6A 5'UTR       24981863//27371828
chr5:89825310-89825311(-) m6A 5'UTR       24981863//27371828
chr5:89825326-89825327(-) m6A 5'UTR       24981863//27371828
chr5:89825337-89825338(-) m6A 5'UTR       24981863//27371828

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-374a-3p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
LYSMD3
Chromatin K562 cells     -
Exosome Blood     -
Nucleoplasm K562 cells     -
Nucleus HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-374a-3p
Interactor2: LYSMD3

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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