Detail Information

Basic Information:


  VIRBase ID:  

HHID00066323

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-374a-3p:           PIP4K2C:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-374a-3p PIP4K2C
miRBase
Accession/Entrez ID		 MIMAT0004688 79837
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - PIP5K2C

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-374a-3p
rs766292977 chrX:74287300    C/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR PIP4K2C
chr12:57992210(+) A-I      intronic
chr12:57989497(+) A-I      intronic
chr12:57991891(+) A-I      intronic
chr12:57992108(+) A-I      intronic
chr12:57991929(+) A-I      intronic
chr12:57991946(+) A-I      intronic
chr12:57992048(+) A-I      intronic
chr12:57993846(+) A-I      intronic
chr12:57991947(+) A-I      intronic
chr12:57991914(+) A-I      intronic
chr12:57988530(+) A-I      intronic
chr12:57991883(+) A-I      intronic
chr12:57990276(+) A-I      intronic
chr12:57991877(+) A-I      intronic
chr12:57992206(+) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED PIP4K2C
chr12:57991883(+) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase PIP4K2C
chr12:57985069-57985070(+) m6A 5'UTR       24981863
chr12:57985153-57985154(+) m6A CDS       24284625
chr12:57985162-57985163(+) m1A CDS       26863196//26863410
chr12:57988964-57988965(+) m6A 3'UTR//CDS       -
chr12:57989686-57989687(+) m6A 3'UTR//CDS//intron       -
chr12:57995392-57995393(+) m6A 3'UTR       24284625//24981863
chr12:57995435-57995436(+) m6A 3'UTR//intron       24284625//24981863
chr12:57995743-57995744(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085
chr12:57995753-57995754(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085
chr12:57995761-57995762(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr12:57995808-57995809(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085
chr12:57995845-57995846(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085
chr12:57996006-57996007(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22608085
chr12:57996016-57996017(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22608085
chr12:57996188-57996189(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085
chr12:57996207-57996208(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085
chr12:57996213-57996214(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085
chr12:57996641-57996642(+) m6A 3'UTR       24209618
chr12:57996820-57996821(+) m6A 3'UTR       24284625//24981863//26404942
chr12:57996957-57996958(+) m6A 3'UTR       24981863//27773535//22608085
chr12:57997013-57997014(+) m6A 3'UTR       24981863//27773535//22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-374a-3p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
PIP4K2C
Chromatin K562 cells     -
Cytosol K562 cells     -
Exosome Blood     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-374a-3p
Interactor2: PIP4K2C

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

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