Detail Information

Basic Information:


  VIRBase ID:  

HHID00066314

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-374a-3p:           SRSF3:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-374a-3p SRSF3
miRBase
Accession/Entrez ID		 MIMAT0004688 6428
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - SFRS3//SRp20

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-374a-3p
rs766292977 chrX:74287300    C/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR SRSF3
chr6:36563776(+) A-I      intronic
chr6:36565707(+) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED SRSF3
chr6:36564896(+) G-T intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase SRSF3
chr6:36562205-36562206(+) m6A 5'UTR//exon       24284625//25456834//24981863//27773535
chr6:36564564-36564565(+) m6A CDS//exon       27773535
chr6:36564594-36564595(+) m6A CDS//exon       27773535
chr6:36564640-36564641(+) m6A CDS//exon       22575960
chr6:36564669-36564670(+) m6A CDS//exon       22575960
chr6:36564735-36564736(+) Tm CDS//exon       -
chr6:36566655-36566656(+) m6A 3'UTR//CDS//exon       22575960
chr6:36567974-36567975(+) m6A 3'UTR//exon//intron       24284625//24981863//27773535
chr6:36569769-36569770(+) m6A 3'UTR//exon       27773535
chr6:36569849-36569850(+) m6A 3'UTR//exon       27773535
chr6:36569911-36569912(+) m6A 3'UTR//exon       27773535
chr6:36570024-36570025(+) m6A 3'UTR//exon       27773535
chr6:36570042-36570043(+) m6A 3'UTR//exon       27773535
chr6:36570053-36570054(+) m6A 3'UTR//exon       27773535
chr6:36570061-36570062(+) m6A 3'UTR//exon       27773535
chr6:36570178-36570179(+) m6A 3'UTR//exon       26404942
chr6:36570195-36570196(+) m6A 3'UTR//exon       26404942
chr6:36570206-36570207(+) m6A 3'UTR//exon       26404942
chr6:36570943-36570944(+) m6A 3'UTR       26404942

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-374a-3p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
SRSF3
Chromatin K562 cells     -
Cytosol HCC cell line (HepG2)     -
Exosome Blood     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)|K562 cells     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-374a-3p
Interactor2: SRSF3

Evidence Support:


Weak-Evidence PAR-CLIP
Support Database ViRBase

References:


PMID 22291592 Target region 3'UTR
Source ViRBase Interactor1 expression None
Tissue or cell line EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells Interactor2 expression None
Description We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.

Starting a new search, please wait ...