Basic Information:

  VIRBase ID:  

HHID00066261

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-26a-2-3p:  MIMAT0004681          PHAF1:  NM_025187     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-26a-2-3p	PHAF1
miRBase Accession/Entrez ID	MIMAT0004681	80262
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	C16orf6//C16orf70//lin-10//LIN10

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-26a-2-3p	rs1158238029 chr12:57824632    C/G rs1386005710 chr12:57824636    A/G rs1386005710 chr12:57824636    A/T rs768371795 chr12:57824638    T/C

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	PHAF1	chr16:67170895(+) A-I      intronic chr16:67170891(+) A-I      intronic chr16:67170762(+) A-I      intronic chr16:67172955(+) A-I      intronic chr16:67156055(+) A-I      intronic chr16:67170927(+) A-I      intronic chr16:67150594(+) A-I      intronic chr16:67150595(+) A-I      intronic chr16:67157421(+) A-I      intronic chr16:67170547(+) A-I      intronic chr16:67170560(+) A-I      intronic chr16:67170585(+) A-I      intronic chr16:67170612(+) A-I      intronic chr16:67170615(+) A-I      intronic chr16:67170919(+) A-I      intronic chr16:67170943(+) A-I      intronic chr16:67170947(+) A-I      intronic chr16:67170964(+) A-I      intronic chr16:67171003(+) A-I      intronic chr16:67171245(+) A-I      intronic chr16:67171286(+) A-I      intronic chr16:67171363(+) A-I      intronic chr16:67171387(+) A-I      intronic chr16:67171402(+) A-I      intronic chr16:67171424(+) A-I      intronic chr16:67171442(+) A-I      intronic chr16:67144848(+) A-I      intronic chr16:67145544(+) A-I      intronic chr16:67171457(+) A-I      intronic chr16:67172840(+) A-I      intronic chr16:67145604(+) A-I      intronic chr16:67172853(+) A-I      intronic chr16:67170911(+) A-I      intronic chr16:67145624(+) A-I      intronic chr16:67156348(+) A-I      intronic chr16:67150552(+) A-I      intronic chr16:67170915(+) A-I      intronic chr16:67156339(+) A-I      intronic chr16:67170736(+) A-I      intronic chr16:67156685(+) A-I      intronic chr16:67170879(+) A-I      intronic chr16:67157512(+) A-I      intronic chr16:67147806(+) A-I      intronic chr16:67173087(+) A-I      intronic chr16:67157238(+) A-I      intronic chr16:67170840(+) A-I      intronic chr16:67152420(+) A-I      intronic chr16:67171270(+) A-I      intronic chr16:67156431(+) A-I      intronic chr16:67156253(+) A-I      intronic chr16:67160673(+) A-I      intronic chr16:67156374(+) A-I      intronic chr16:67156456(+) A-I      intronic chr16:67171321(+) A-I      intronic chr16:67150716(+) A-I      intronic chr16:67156266(+) A-I      intronic chr16:67158751(+) A-I      intronic chr16:67171046(+) A-I      intronic chr16:67153563(+) A-I      intronic chr16:67145791(+) A-I      intronic chr16:67171339(+) A-I      intronic chr16:67156307(+) A-I      intronic chr16:67151575(+) A-I      intronic chr16:67156749(+) A-I      intronic chr16:67152940(+) A-I      intronic chr16:67170216(+) A-I      intronic chr16:67156771(+) A-I      intronic chr16:67151620(+) A-I      intronic chr16:67164901(+) A-I      intronic chr16:67177294(+) A-I      intronic chr16:67155382(+) A-I      intronic chr16:67170589(+) A-I      intronic chr16:67149798(+) A-I      intronic chr16:67170667(+) A-I      intronic chr16:67171072(+) A-I      intronic chr16:67152468(+) A-I      intronic chr16:67156387(+) A-I      intronic chr16:67149846(+) A-I      intronic chr16:67150511(+) A-I      intronic chr16:67170897(+) A-I      intronic chr16:67156023(+) A-I      intronic chr16:67173106(+) A-I      intronic chr16:67170541(+) A-I      intronic chr16:67150602(+) A-I      intronic chr16:67177989(+) A-I      intronic chr16:67171483(+) A-I      intronic chr16:67170712(+) A-I      intronic chr16:67170625(+) A-I      intronic chr16:67151591(+) A-I      intronic chr16:67160693(+) A-I      intronic chr16:67170651(+) A-I      intronic chr16:67152150(+) A-I      intronic chr16:67151951(+) A-I      intronic chr16:67151584(+) A-I      intronic chr16:67177730(+) A-I      intronic chr16:67171291(+) A-I      intronic chr16:67156291(+) A-I      intronic chr16:67171365(+) A-I      intronic chr16:67170705(+) A-I      intronic chr16:67170586(+) A-I      intronic chr16:67171347(+) A-I      intronic chr16:67146178(+) A-I      intronic chr16:67157499(+) A-I      intronic chr16:67171277(+) A-I      intronic chr16:67157440(+) A-I      intronic chr16:67145551(+) A-I      intronic chr16:67145627(+) A-I      intronic chr16:67145628(+) A-I      intronic chr16:67171474(+) A-I      intronic chr16:67170643(+) A-I      intronic chr16:67152697(+) A-I      intronic chr16:67146226(+) A-I      intronic chr16:67156347(+) A-I      intronic chr16:67170525(+) A-I      intronic chr16:67148202(+) A-I      intronic chr16:67149874(+) A-I      intronic chr16:67148184(+) A-I      intronic chr16:67170611(+) A-I      intronic chr16:67172891(+) A-I      intronic chr16:67156449(+) A-I      intronic chr16:67170937(+) A-I      intronic chr16:67170652(+) A-I      intronic chr16:67151944(+) A-I      intronic chr16:67171012(+) A-I      intronic chr16:67156373(+) A-I      intronic chr16:67171388(+) A-I      intronic chr16:67148166(+) A-I      intronic chr16:67171348(+) A-I      intronic chr16:67170555(+) A-I      intronic chr16:67156367(+) A-I      intronic chr16:67170647(+) A-I      intronic chr16:67157425(+) A-I      intronic chr16:67171361(+) A-I      intronic chr16:67151588(+) A-I      intronic chr16:67171496(+) A-I      intronic chr16:67177785(+) A-I      intronic chr16:67170872(+) A-I      intronic chr16:67147867(+) A-I      intronic chr16:67152827(+) A-I      intronic chr16:67153713(+) A-I      intronic chr16:67177332(+) A-I      intronic chr16:67170616(+) A-I      intronic chr16:67170763(+) A-I      intronic chr16:67157255(+) A-I      intronic chr16:67158494(+) A-I      intronic

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-26a-2-3p	Exosome Plasma     23663360 Exosome B cell lymphoma cell lines|EBV-transformed lymphoblastoid B cells     25242326 Exosome Breast milk     - Microvesicle Fibroblasts|Mesenchymal stem cells     -
	PHAF1	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol HCC cell line (HepG2)     - Exosome Blood     - Insoluble cytoplasm HCC cell line (HepG2)     - Membrane HCC cell line (HepG2)     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|HeLa-S3 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-26a-2-3p
Interactor2: PHAF1

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.