Basic Information:

  VIRBase ID:  

HHID00066248

  Virus:  

Human gammaherpesvirus 4 (Epstein-Barr virus, EPV)

  Host:  

Homo sapiens

  Confidence Score:  

0.4752

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-26a-2-3p:  MIMAT0004681          RAB5IF:  NM_001374178     

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Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-26a-2-3p	RAB5IF
miRBase Accession/Entrez ID	MIMAT0004681	55969
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	C20orf24//PNAS-11//RCAF1//RIP5

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-26a-2-3p	rs1158238029 chr12:57824632    C/G rs1386005710 chr12:57824636    A/G rs1386005710 chr12:57824636    A/T rs768371795 chr12:57824638    T/C

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	RAB5IF	chr20:35239593(+) A-I      intronic chr20:35237084(+) A-I      intronic chr20:35239448(+) A-I      intronic chr20:35236717(+) A-I      intronic chr20:35239602(+) A-I      intronic chr20:35239623(+) A-I      intronic chr20:35238509(+) A-I      intronic chr20:35238550(+) A-I      intronic chr20:35238880(+) A-I      intronic chr20:35239654(+) A-I      intronic chr20:35239580(+) A-I      intronic chr20:35239567(+) A-I      intronic chr20:35239492(+) A-I      intronic chr20:35239085(+) A-I      intronic chr20:35238983(+) A-I      intronic chr20:35236838(+) A-I      intronic chr20:35239522(+) A-I      intronic chr20:35237746(+) A-I      intronic chr20:35239039(+) A-I      intronic chr20:35238977(+) A-I      intronic chr20:35238572(+) A-I      intronic chr20:35239510(+) A-I      intronic chr20:35239659(+) A-I      intronic chr20:35238850(+) A-I      intronic chr20:35239576(+) A-I      intronic chr20:35239775(+) A-I      intronic chr20:35238987(+) A-I      intronic chr20:35238608(+) A-I      intronic chr20:35237053(+) A-I      intronic chr20:35237808(+) A-I      intronic chr20:35239532(+) A-I      intronic chr20:35239573(+) A-I      intronic chr20:35238567(+) A-I      intronic chr20:35236789(+) A-I      intronic chr20:35239744(+) A-I      intronic chr20:35239656(+) A-I      intronic chr20:35238566(+) A-I      intronic chr20:35238471(+) A-I      intronic chr20:35239745(+) A-I      intronic chr20:35239493(+) A-I      intronic chr20:35239628(+) A-I      intronic chr20:35239851(+) A-I      intronic chr20:35239534(+) A-I      intronic chr20:35238431(+) A-I      intronic

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-26a-2-3p	Exosome Plasma     23663360 Exosome B cell lymphoma cell lines|EBV-transformed lymphoblastoid B cells     25242326 Exosome Breast milk     - Microvesicle Fibroblasts|Mesenchymal stem cells     -
	RAB5IF	Exosome Blood     - Nucleolus K562 cells     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-26a-2-3p
Interactor2: RAB5IF

Evidence Support:

Weak-Evidence	PAR-CLIP
Support Database	ViRBase

References:

PMID	22291592	Target region	3'UTR
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	EF3D-AGO2 cells//LCL35 cells//LCL-BAC cells//LCL-BAC-D1 cells//LCL-BAC-D3 cells	Interactor2 expression	None
Description	We identified 7, 827 miRNA-interaction sites in 3, 492 cellular 3'UTRs. 531 of these sites contained seed matches to viral miRNAs.Table S6: High confidence miRNA-interaction sites in 3'UTRs.